Navigation Links
Disinfectant Misuse Might Help Germs Resist Antibiotics

But it's unclear if this would happen outside the lab, expert says

TUESDAY, Dec. 29 (HealthDay News) -- The incorrect use of a disinfectant could cause some germs to develop resistance to antibiotics, new research suggests.

However, the findings haven't been proven outside of the laboratory and they don't suggest that there's anything wrong with disinfectants that are used properly. "It is OK to use disinfectants. Just don't misuse or overuse them," said study co-author Gerard T.A. Fleming.

It's well-known that the widespread use of antibiotics is thought to be making germs stronger because some bacteria learn how to bypass the drugs. In the new study, researchers sought to find out if a disinfectant could have a similar effect on a germ called Pseudomonas aeruginosa, which can cause disease in people with compromised immune systems and is a significant cause of hospital-acquired infections.

The disinfectant, known as benzalkonium chloride, is used in a variety of skin cleansers and disinfectant products along with face creams and spermicides, said Fleming, a scientist at the National University of Ireland in Galway. "It is seen as a good disinfectant in that it generally does not harm if it comes into contact with skin," he explained.

In the laboratory, researchers added low levels of the disinfectant to a solution that included the bacteria. The findings are published in the January issue of the journal Microbiology.

The researchers found that the bacteria mutated and became resistant to the powerful antibiotic known as ciprofloxacin (Cipro) after being exposed to the disinfectant. Cipro is best known as a drug used to treat people exposed to anthrax.

The bacteria also became resistant to the disinfectant.

There is a caveat to the research: It took place in the laboratory, not in a home or a hospital, where the germ in question is most likely to cause problems. The study doesn't conclusively demonstrate what would happen in "the real environment," cautioned Dr. Pascal James Imperato, a professor at State University of New York Downstate Medical Center School of Public Health.

Still, "the study clearly demonstrates the need for further research into this area," Imperato said.

The findings indicate that people should use disinfectants at the correct level and "not be tempted to dilute them down so that they go further in an attempt to save money," Fleming said. "Disinfectants work at the concentration stated on the bottle, but if they are diluted to a level where microorganisms can evolve, resistance can build up."

Also, it's important to give disinfectants time to work, he noted.

"I am concerned that if we do not use disinfectants properly in the home, that we might be affording microorganisms the opportunity of building up resistance to disinfectants and antibiotics," Fleming said.

"To put it simply, disinfectants are our first line of defense against harmful germs," Fleming added. "Antibiotics are our second line of defense in case of infection. Our study has shown that it is possible to corrupt the first and second line of defense. What then are we left with?"

Another study that was released last week illustrates the seriousness of the problem.

Researchers from a Washington, D.C.-based project funded by the Robert Wood Johnson Foundation reported that a particularly resistant bacteria is flourishing in hospitals across the country.

Poring over records from 300 hospitals, the scientists found there was more than a 300 percent increase in the proportion of Acinetobacter cases resistant to the last-resort antibiotic imipenem (Primaxin) between 1999 and 2006.

These infections, which typically surface in patients in intensive care units, usually lead to severe pneumonias or bloodstream infections, and even powerful antibiotics can't always stop the infection.

The study, reported online Dec. 23 in the journal Infection Control and Hospital Epidemiology, will appear in the journal's February print edition.

More information

Learn more about antibacterial resistance from the U.S. Centers for Disease Control and Prevention.

SOURCES: Gerard Fleming, Ph.D., scientist, National University of Ireland, Galway; Pascal James Imperato, M.D., professor, State University of New York Downstate Medical Center School of Public Health, New York City; January 2010, Microbiology; Dec. 23, 2009, Infection Control and Hospital Epidemiology, online

Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. TouchSurfaces.Org Launches Public Health Information Site for Advanced Disinfectant Solutions for Use Around Children and Pets
2. Reportlinker Adds Antiseptics and Disinfectants Report
3. Camp High Harbour Response to Flu Outbreak Includes SpectraSan 24 Disinfectant
4. Oust(R) Surface Disinfectant & Air Sanitizer Effective Against H1N1
5. BioTech Medical Well-Positioned to Immediately Respond to Swine Flu Emergency with SDC-Based SpectraSan 24 Disinfectant
6. Whats in your water?: Disinfectants create toxic by-products
7. Sterifide Laboratories to Launch Powered by SDC OneShot Plus Disinfectant and Deodorizer
8. PURE Bioscience Announces Brazilian Regulatory Approval for SDC-Based Hospital-Grade Disinfectants
9. BioTech Medical LLC Launches Leading Edge Powered by SDC Disinfectant Products
10. Linkwell Corporation Runs 24/7 Disinfectant Operations to Support Chinas Earthquake Relief Efforts
11. New Clorox disinfectant is EPA registered to kill both known types of MRSA
Post Your Comments:
(Date:11/29/2015)... ... November 29, 2015 , ... Key Housing, a top-rated corporate housing service ... 2015, featured apartment community: Epic. In showcasing this featured apartment community in San Jose, ... Area rental market to efficiently find housing suitable to their needs by showcasing quality ...
(Date:11/28/2015)... PITTSBURGH, PA (PRWEB) , ... November 28, 2015 , ... ... Manalapan, N.J., has created the COUCH BUDDY. "I conceived of this design due to ... more comfort for couch users. It promotes relaxation and convenience, as well as increases ...
(Date:11/27/2015)... (PRWEB) , ... November 28, 2015 , ... There is ... we outperform our billings from last year? , This question has not been an ... are coming to the retirement age and the younger workforce don’t share the same ...
(Date:11/27/2015)... ... ... According to an article published November 15th by ABC News, ... in light of the recent terrorist attacks in Paris, other cities are taking extra ... from reaching U.S. soil. Especially around special events that may be high-profile in nature, ...
(Date:11/27/2015)... ... November 27, 2015 , ... An inventor, from Hopkinsville, ... prescription medications at home, so he invented the patent-pending ELECTRONIC M.D. , The ... medications. In doing so, it could help to prevent potential overdose situations. As ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... PHILADELPHIA , Nov. 27, 2015  Lannett ... that it has completed the acquisition of Kremers ... pharmaceuticals subsidiary of global biopharmaceuticals company UCB S.A. ... --> Lannett has acquired KU from UCB ... to certain adjustments, including a customary working capital ...
(Date:11/26/2015)... WILMINGTON, North Carolina , 26 november ... Laboratories, Inc. (AAIPharma/CML) kondigt de geplande investering ... de uitbreiding van de laboratoria en het ... . De uitbreiding zal resulteren in ... waarmee wordt voldaan aan de groeiende behoeften ...
(Date:11/26/2015)... -- 3D bioprinting market is expected to ... report by Grand View Research Inc. Rising prevalence of chronic ... transplantation is expected to boost the market growth, as 3D ... --> 3D bioprinting market is expected to ... report by Grand View Research Inc. Rising prevalence of chronic ...
Breaking Medicine Technology: