Navigation Links
Discovery opens door to 'personalized' asthma therapy
Date:1/17/2008

GALVESTON, Texas In the last few years, personalized medicine using genetic or other molecular biology-based diagnostic tests to customize treatment for a particular patient has emerged as a powerful new tool for health care.

Therapy guided by genetic testing has proven highly successful in treating some types of leukemia and breast and lung cancer. Similar personalized therapies are on the horizon for other types of cancer, as well as diabetes, heart disease and other deadly disorders.

Now, University of Texas Medical Branch at Galveston (UTMB) researchers and their colleagues elsewhere have taken the first steps toward bringing the methods of personalized medicine to asthma.

Applying state-of-the-art protein screening techniques to samples taken from 84 asthmatic volunteers, theyve made the first identification of different subtypes of asthma based on distinct protein profiles, unique combinations of 10 or more proteins with which they are associated.

One of these profiles corresponds to a variety of severe, treatment-resistant asthma that, while rare, is responsible for 40 to 50 percent of the total health care costs associated with the disease.

We know that in asthma some people respond to very specific types of therapies and others dont, said Dr. Allan Brasier, director of UTMBs Sealy Center for Molecular Medicine and a senior author of a paper on the study appearing in the just-published January issue of the Journal of Allergy and Clinical Immunology (online at http://journals.elsevierhealth.com/periodicals/ymai). Being able to discover different asthma subtypes should allow us to tailor our treatments to increase the odds of a positive response, Brasier added.

To obtain their samples, researchers squirted a small amount of saline solution through tiny tubes into the anesthetized volunteers lungs. They then sucked the saline back out, bringing with it proteins washed free from walls of the network
'/>"/>

Contact: Tom Curtis
tcurtis@utmb.edu
409-772-2455
University of Texas Medical Branch at Galveston
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Linguamatics and 81qd Sign Multi-Year Collaboration in Knowledge Discovery for Product Life Cycle Management
2. Fight against hay fever and other allergies helped by new immune system discovery
3. Discovery Healths Fifth Annual National Body Challenge Takes a Stand Against Obesity by Offering the Keys to Adopting a Healthy, Active Lifestyle
4. Overweight Twins Battle the Bulge and Gain A New Lease on Life in National Body Challenge: Twins Edition on Discovery Health
5. Kaiser Permanente and Discovery Health Team Up to Fight Childhood Obesity Epidemic
6. Panomics Inc.: Recipient of the Frost & Sullivan 2007 United States Drug Discovery Technologies Entrepreneurial Company of the Year Award
7. OHSU Cancer Institute research discovery opens new window to understanding chronic myeloid leukemia
8. Orion Pharma Selects ChemDiv as A Partner in Drug Discovery Services
9. BioDiscovery Joins Illumina Connect Bioinformatics Program
10. Discovery Health Travels the World to Present the Groundbreaking Documentary - Diabetes: A Global Epidemic
11. Beactica Announces Drug Discovery Collaboration With Arrow Therapeutics
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... study finds a wide range of epigenetic changesalterations in ... environmental exposuresin children with Crohn,s disease (CD), reports ... Crohn,s & Colitis Foundation of America (CCFA). The ... a part of Wolters Kluwer Health . ... in several regions of the genome in children with CD, ...
(Date:8/22/2014)... Women treated for the cancer Hodgkin lymphoma will be ... after researchers estimated their risk of premature menopause with ... Journal of the National Cancer Institute , are ... women in England and Wales treated for the cancer ... Previous research has suggested that women with Hodgkin lymphoma ...
(Date:8/22/2014)... The New Jersey Institute for Food, Nutrition ... of New Jersey has joined forces with ChopChop ... young people about health and nutrition in a new ... organizations. , The partnership will encompass quarterly custom editions ... video communications. ChopChop Magazine features plenty of child-friendly ...
(Date:8/22/2014)... (PRWEB) August 22, 2014 Ticket Down ... in East Hartford, CT at Rentschler Field. There has never ... the United States than right now. After the strong showing at ... fans and the sport is being featured in large stadiums around ... an eight team tournament that featured some of the best club ...
(Date:8/22/2014)... Statesville, N.C. (PRWEB) August 22, 2014 ... the managed employee reward and recognition industry, has received ... With an extraordinary growth rate of 134%, TharpeRobbins remains ... companies in North America. TharpeRobbins was previously on the ... are honored to be included in this distinguished list ...
Breaking Medicine News(10 mins):Health News:Study shows epigenetic changes in children with Crohn's disease 2Health News:Scientists map risk of premature menopause after cancer treatment 2Health News:New Jersey Institute for Food, Nutrition & Health to Launch Innovative Partnership with Award-Winning Children’s Anti-Obesity Organization, ChopChop Kids 2Health News:New Jersey Institute for Food, Nutrition & Health to Launch Innovative Partnership with Award-Winning Children’s Anti-Obesity Organization, ChopChop Kids 3Health News:USA vs. Ecuador Tickets: Ticket Down Slashes USA (USMT) vs. Ecuador Tickets at Rentschler Field in East Hartford on Oct. 10th 2Health News:USA vs. Ecuador Tickets: Ticket Down Slashes USA (USMT) vs. Ecuador Tickets at Rentschler Field in East Hartford on Oct. 10th 3Health News:For The Fourth Time - TharpeRobbins Earns A Place On Prestigious Inc. Magazine 500|5000 List 2Health News:For The Fourth Time - TharpeRobbins Earns A Place On Prestigious Inc. Magazine 500|5000 List 3
... KUNMING, China, Sept. 13 /Xinhua-PRNewswire-FirstCall/ -- China,Shenghuo ... KUN ), which is engaged in ... nutritional supplement and cosmetic,products in the People,s ... the full-scale launch of its 12Ways(R) Chinese ...
... Sept. 13 Scimitar Equity Research, Inc.,(Scimitar) today ... Bulletin,Board: ABOS) entitled: "Enhancing the Recovery of Patients ... research review is,available on Scimitar,s website: http://www.scimitarequity.com ... Device The SEPET(TM) Liver Assist Device is ...
... correlation, with risk doubling as blood cells decline , ... declining blood platelet counts may be at increased risk ... behavioral and motor skill problems, researchers report. , Researchers ... Johns Hopkins University School of Medicine in Baltimore studied ...
... (Sept. 10, 2007) -- For high-blood-pressure patients, preventing or ... risk of heart failure. The study is published in ... by physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in ... all high-blood-pressure patients, or 12 million Americans, have LVH ...
... Health Corp. is the Distributor of the Popular Dietary Supplement ... ... Health Corp. is proud to,announce its retail presence has expanded again ... and Sweet Bay,Supermarkets. LipidShield Plus is the popular NATURAL breakthrough ...
... Reports Solid Progress on Child Survival, NEW YORK, Sept. ... below 10 million per year to 9.7 million,down from almost ... an historic moment," said UNICEF Executive Director Ann M.,Veneman. "Now ... for the,achievement of the Millennium Development Goals." Among these ...
Cached Medicine News:Health News:China Shenghuo Pharmaceutical Holdings, Inc. Begins Full-Scale Launch of 12Ways(R) Chinese Herbal Skin Care Product Line 2Health News:China Shenghuo Pharmaceutical Holdings, Inc. Begins Full-Scale Launch of 12Ways(R) Chinese Herbal Skin Care Product Line 3Health News:China Shenghuo Pharmaceutical Holdings, Inc. Begins Full-Scale Launch of 12Ways(R) Chinese Herbal Skin Care Product Line 4Health News:Arbios Systems, Inc's Q2/07 Analyst Review Issued by Scimitar Equity Research, Inc. 2Health News:Falling Platelet Counts May Signal HIV-Linked Dementia 2Health News:Preventing or reducing enlarged heart decreases risk of heart failure 2Health News:New Health Corp. Announces the Addition of Hannaford Bros., Kash N Karry and Sweet Bay Supermarkets to its Retail Outlets 2Health News:Child Deaths Fall Below 10 Million For First Time 2Health News:Child Deaths Fall Below 10 Million For First Time 3Health News:Child Deaths Fall Below 10 Million For First Time 4
(Date:8/21/2014)... 2014 Nektar Therapeutics (NASDAQ: ... positive results from its Phase 3 pivotal clinical ... recombinant factor VIII (rFVIII) treatment for hemophilia A ... its primary endpoint in reducing annualized bleed rates ... on-demand arm. Top-line results from the ...
(Date:8/21/2014)... The spinal column is one of the most delicate and ... from the brain through the column control many key functions ... here can be life altering, and leave the victim in ... body. Though back injury and disease can have an intensely ... available to make things better than ever before. Laser ...
(Date:8/21/2014)... 21, 2014 /CNW/ - Eisai Limited is pleased to support ... first-of-its-kind comic book available in Canada . ... specifically to educate children and their parents about epilepsy, the ... affecting more than 300,000 Canadians. Eisai is guided by a ... in which the patient is central – there was a ...
Breaking Medicine Technology:Baxter Announces Positive Top-Line Results from Its Phase 3 Study of BAX 855, Extended Half-Life Recombinant FVIII for Hemophilia A Patients 2Baxter Announces Positive Top-Line Results from Its Phase 3 Study of BAX 855, Extended Half-Life Recombinant FVIII for Hemophilia A Patients 3Baxter Announces Positive Top-Line Results from Its Phase 3 Study of BAX 855, Extended Half-Life Recombinant FVIII for Hemophilia A Patients 4Baxter Announces Positive Top-Line Results from Its Phase 3 Study of BAX 855, Extended Half-Life Recombinant FVIII for Hemophilia A Patients 5Don't Live in Pain: Four Life Improving Benefits of Back Surgery 2Eisai Pleased to Support Canadian Epilepsy Alliance Comic Book that Teaches Children About Epilepsy 2
... N.J., Feb. 3, 2011 BioNeutral Group, Inc. (OTC ... science technology-based company, today announced the formation of BioNeutral ... Inc., and the appointment of Frank Battafarano as the ... BioNeutral Services will market and distribute a ...
... 2011 A VANIR Pharmaceuticals, Inc. ... the three months ended December 31, 2010. For the ... $12.1 million, or $0.11 loss per share, compared with a net ... same period in fiscal 2010. Net revenues consisting primarily of royalty ...
Cached Medicine Technology:BioNeutral Group Announces the Formation of Kentucky-Based BioNeutral Services, Inc. and the Appointment of Frank Battafarano as Chairman and CEO of BioNeutral Services, Inc. 2BioNeutral Group Announces the Formation of Kentucky-Based BioNeutral Services, Inc. and the Appointment of Frank Battafarano as Chairman and CEO of BioNeutral Services, Inc. 3AVANIR Pharmaceuticals Announces Fiscal 2011 First Quarter Financial Results 2AVANIR Pharmaceuticals Announces Fiscal 2011 First Quarter Financial Results 3AVANIR Pharmaceuticals Announces Fiscal 2011 First Quarter Financial Results 4AVANIR Pharmaceuticals Announces Fiscal 2011 First Quarter Financial Results 5AVANIR Pharmaceuticals Announces Fiscal 2011 First Quarter Financial Results 6
... Sterile Bad-Parker blades offer the ... stainless steel technology, plus the exclusive ... and strength. Brad-Parker brand producer offer ... handles and disposable scalpels. Every blade ...
BD Beaver implant blade, 5.1 mm, angled 45, bevel up. matte finish. Designed for widening the incision for lens implantation. Beaver implant blades put precision and control in your hands, sterile....
BD Beaver Meniscus blade, 7 mm flat (4/bx, 1 bx/ca), specially designed maximum leverage and visibility, cutting edge: 7 mm, sterile....
... fit standard trial frames. They are made of optical ... display box. There are two sets available providing a ... that is that a patient can wear the prism ... allow the patient to adapt to the use of ...
Medicine Products: