Navigation Links
Discovery of mechanism in brain cell injury in Huntington's offers new treatment approaches
Date:1/27/2010

searchers did find a way to mitigate damage and slow disease progression at early stages of the diseaseusing Memantine, a drug currently used to treat Alzheimer's disease.

"Memantine in low dose works by preferentially blocking the activity of NMDA receptors outside the synapse," says Dr. Michael Hayden, director of the Centre for Molecular Medicine and Therapeutics, professor in the UBC Department of Medical Genetics, and co-author on the study.

"It was previously shown to reverse deficits and damage in late stages of animal models of Huntington's disease, but we found it could improve learning and cell survival signaling even at early stages of the disease," says Hayden. "A small human clinical trial of Memantine for Huntington's disease has also recently shown positive effects. Larger, international clinical trials are now being planned."

"Memantine's beneficial effects appear to be dose-specific," Raymond adds. "Before it can be prescribed to treat Huntington's disease, we need to know how to determine appropriate dosing and whether it interferes with other essential cellular and brain functions."


'/>"/>

Contact: Melissa Ashman
mashman@brain.ubc.ca
604-827-3396
University of British Columbia
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Discovery of sugar sensor in intestine could benefit diabetes
2. Discovery suggests location of genes for breast density, a strong risk factor for breast cancer
3. Stem cell research produces a key discovery for Fragile X Syndrome
4. Welch Foundation gives $1.6 million for drug discovery research
5. New discovery leaves blood-doping athletes scratching their heads
6. Chemical Diversity Initiates International Prostrate Cancer Discovery Partnership
7. New discovery leaves blood-doping athletes scratching their heads
8. Discovery of widespread tumor growth gene holds promise for effective anti-cancer treatment
9. Discovery supports theory of Alzheimers disease as form of diabetes
10. Discovery Health CME Explores the Benefits and Risks of Aspirin in Aspirin Therapy: Maximizing the Benefits
11. New discovery may improve treatment of one of the worlds leading causes of blindness
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... CA (PRWEB) August 28, 2014 ... small and mid-sized healthcare organizations, today announced that it ... online appointment company ZocDoc , to head their ... company has created a sales management position. , “I’m ... startup like DoctorBase that already has so much traction ...
(Date:8/28/2014)... August 28, 2014 Top 10 ... web hosting companies and announces Bluehost, HostMonster ( ... suppliers for the webmasters worldwide who want to ... , As the world’s most popular server-side scripting ... many other general-purpose programs. It is now installed ...
(Date:8/28/2014)... MarijuanaDoctors.com is enthralled to announce the ... of Livermore, California. As always, MarijuanaDoctors.com prides itself on ... and in accordance with that, we are excited to ... practice. , Initially finding his calling for healing and ... was shaped by his mother’s severe arthritis to finally ...
(Date:8/28/2014)... The revenue cycle process touches on nearly ... a patient books an appointment with a physician’s office, ... for services rendered to the healthcare provider. Medorizon ... the RCM process down to a science. Over the ... place in nearly every healthcare facility around the globe. ...
(Date:8/28/2014)... The next episode of “Extreme Weight Loss” ... He’s a drama coach who longs to audition for ... achieving that dream impossible. , Featuring a unique, non-competitive ... Tuesday, September 2 (9:00-11:00 p.m., ET/PT) on the ABC ... smile on the outside to hide the self-doubt and ...
Breaking Medicine News(10 mins):Health News:DoctorBase Hires Josh Angeles as Vice-President of Sales 2Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 2Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 3Health News:Army Colonel Dr. James Patel Joins the Medical Marijuana Industry 4Health News:Tips on Automating the Revenue Cycle Process with Medical Billing 2Health News:Tips on Automating the Revenue Cycle Process with Medical Billing 3Health News:“Extreme Weight Loss”: Rod’s Journey Begins at the University of Colorado Anschutz Health and Wellness Center 2
... January 14, 2009 Obesity continues to increase for ... Mexican-American women. Between the ages of 35-44, there are ... and 575,000 Mexican-American women who are obese. A new ... reveals that there is an increased risk for ...
... LIVONIA, Mich., Jan. 14 On the heels of ... 11 states, American Community,Mutual Insurance Company today announced that ... Indiana. Designed to help consumer,s hold,down their medical expenses, ... through independent agents for a coverage effective date beginning,March ...
... much about it. FlameEz.com is launched to provide the latest information ... of the most feared illnesses in middle and old age. ... ... Millions of Americans are affected by chronic inflammation without knowing much ...
... SHANGHAI, China, Jan. 14 /PRNewswire-Asia-FirstCall/ -- China-Biotics, ... Company"), a leading Chinese firm,specializing in the ... products, today announced it has signed contracts,with ... Co., Ltd. ("Yuejia Food"),Shandong Huwa Dairy Industry ...
... N.Y., Jan. 14 /PRNewswire/ -- Scarguard Labs, ... of scars and other dermatological problems through the use ... system, announced it has appointed Richard E. Pino as ... Company,s finance, accounting, and treasury functions and will report ...
... in outbreak rises to 425 in 43 states, CDC says ... of people sickened by salmonella-contaminated peanut butter rose to 425 ... death in Minnesota and two in Virginia were probably tied ... the three people, whose names and hometowns haven,t been released, ...
Cached Medicine News:Health News:Economic status affects obesity rates in Mexican-American and white women 2Health News:American Community Introduces Community Flex(TM), an Affordable Health Plan in Arizona and Indiana 2Health News:Control of Inflammation May Benefit Many of the Most Feared Illnesses in Middle and Old Age 2Health News:Control of Inflammation May Benefit Many of the Most Feared Illnesses in Middle and Old Age 3Health News:China-Biotics, Inc. Signs Agreements With Four Additional Food Manufacturers 2Health News:China-Biotics, Inc. Signs Agreements With Four Additional Food Manufacturers 3Health News:China-Biotics, Inc. Signs Agreements With Four Additional Food Manufacturers 4Health News:Scarguard Labs, LLC Appoints Richard E. Pino as CFO 2Health News:Salmonella Linked to Deaths in Virginia, Minnesota 2Health News:Salmonella Linked to Deaths in Virginia, Minnesota 3
(Date:8/27/2014)... , Aug. 27, 2014 Kewaunee Scientific Corporation ... of Directors increased its quarterly cash dividend by 9% ... per outstanding share, beginning with the dividend payable on ... close of business on September 8, 2014. ... in 1906, Kewaunee Scientific Corporation is a recognized global ...
(Date:8/27/2014)... -- Columbia Laboratories, Inc. (Nasdaq: CBRX ) ("Columbia" ... trial manufacturing, and advanced analytical and consulting services to ... at the upcoming Rodman & Renshaw 16 th ... New York . The Company will present ... at the New York Palace Hotel. ...
(Date:8/27/2014)... and NINGBO, China , Aug. ... Ningbo Menovo Pharmaceutical Co., Ltd, ("Menovo") today announced they ... of generic pharmaceuticals, primarily targeting the United ... agreement, Amerigen and Menovo will jointly develop products for ... . Menovo will be responsible for manufacturing API ...
Breaking Medicine Technology:Amerigen Pharmaceuticals Limited and the Ningbo Menovo Pharmaceutical Co., Ltd, today announced they had entered into a collaboration agreement regarding the development of generic pharmaceuticals, primarily targeting the United States market 2
... N.J., Feb. 15, 2011 Daiichi Sankyo, Inc. (DSI), ... facility in Bethlehem Township, Pennsylvania from Amcor, a global ... leverage existing resources to more cost-effectively supplement its operations ... expected to be operational in the summer or early ...
... MAHWAH, N.J., Feb. 15, 2011 Stryker Corporation,s Orthopaedics ... most recognizable names and personalities in professional golf, has ... of the sport and current member of the PGA ... Triathlon ® Knee System in November 2009 and ...
Cached Medicine Technology:Daiichi Sankyo, Inc. Acquires First US-Based Packaging and Manufacturing Facility 2Fred Funk Becomes Spokesperson for Stryker Orthopaedics 2Fred Funk Becomes Spokesperson for Stryker Orthopaedics 3
... Chalam 15° Prism are designed ... are recommended for tractional retinal ... Rhegmatogenus retinal detachment. They can ... and other midperipheral laser applications. ...
... The High-Mag 1.5x ... internal limiting membrane peeling ... optic nerve neurotomy, sheathotomy ... traditional macular edema and ...
... visualization of virtually the entire retina including ... of the lens on the eye. It ... giant retinal tears, diagnosing and treating anterior ... retina in a vitreous cavity filled with ...
... higher magnification and increased stereopsis, ... suited for detailed visualization to ... Retinal is ideal for vitrectomy ... peeling in proliferative vitreoretinopathy extending ...
Medicine Products: