Navigation Links
Discovery of key malaria proteins could mean sticky end for parasite
Date:7/9/2008

ofessor Cowman. "They also suggest that a drug that targets the 'stickiness' proteins could be an effective treatment for malaria."

Malaria is currently treated using drugs that kill the parasites. However, as the parasites evolve, they have become increasingly resistant to existing treatments such as chloroquine and mefloquine, and there is some evidence of increasing resistance against even the most effect and newest treatments, artemisinin derivatives such as artesunate.

"Malaria parasites are evolving, making our current treatments increasingly less effective," says Professor Alister Craig from the Liverpool School of Tropical Medicine, who collaborated on the project. "This suggests we need to approach the problem using a different strategy. A drug which prevents disease rather than killing the parasite might be important because it could retain natural inoculation in the patient, limiting damage caused by the parasite and providing protection from further infection."

The research was carried out by interfering with the function of specific genes on a scale not previously attempted in the malaria parasite. By blocking or "knocking out" the function of these genes the team was able to identify those important for allowing the parasite to stick to the walls of blood vessels.


'/>"/>

Contact: Craig Brierley
c.brierley@wellcome.ac.uk
44-207-611-7329
Wellcome Trust
Source:Eurekalert

Page: 1 2

Related medicine news :

1. 9/11 Workers Refute Citys Allegation of Discovery Abuse and Malingering
2. Discovery of gene mechanism could bring about new ways to treat metastatic cancer
3. MYSTERY ER Season 2 Takes Viewers Behind the Curtain for Real-Life Medical Mysteries on Discovery Health
4. NIAID creates HIV vaccine discovery branch
5. Could new discovery about a shape-shifting protein lead to a mighty morpheein bacteria fighter?
6. Core Informatics Deploys Core LIMS to Support Antibody Discovery at Fabrus
7. Dynamin drug discovery team win prestigious international epilepsy grant
8. Singapore Is One of the Fastest Growing Bioclusters in Asia; Wave of Investments in Drug Discovery and Translational Research
9. New Molecule Discovery Shows Promise Against Tamoxifen-Resistant Breast Cancers
10. Stem cell discovery sheds light on placenta development
11. Discovery of new signal pathway important to diabetes research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/22/2014)... Today, Dylan Queen, a renowned brand in ... dresses; the business offers a wide range of special ... worldwide, allowing them to create multiple looks easily. , ... new collection of chic wedding dresses has been prepared ... at discounted rates now. Dylan Queen can always create ...
(Date:11/22/2014)... (PRWEB) November 22, 2014 Discount-Dress.com ... aim of the firm is to increase the company’s online ... introduced a new selection of bridesmaid dresses and announced a ... offer is valid until Dec. 30, 2014. All the dresses ... also inexpensive. , In fact, Discount-Dress.com is very good ...
(Date:11/22/2014)... (PRWEB) November 22, 2014 "My friend ... pain caused by the machine," said an inventor from ... had to go back a second time because the ... idea." , She developed the patent-pending MAMO EASY to ... cancer. The design saves the patient from the pain ...
(Date:11/22/2014)... SATURDAY, Nov. 22, 2014 (HealthDay News) -- The wide ... can pose a threat for people with food allergies, ... there are so many types of food allergies that ... over the holidays," Dr. Guha Krishnaswamy, director of allergy ... said in a hospital news release. "If you ...
(Date:11/22/2014)... 2014 This month has been a historical ... has received many positive reviews from some renowned review websites. ... products by launching a new selection of wonderful sexy wedding ... can enjoy free shipping and up to an 80% discount ... can always find the most suitable dress at Angeldress.co.uk, which ...
Breaking Medicine News(10 mins):Health News:Dylan Queen Introduces Its New Wedding Dresses 2Health News:Bridesmaid Dresses Introduced by Famous Company Discount-Dress.com For The New Year 2015 2Health News:'Tis the Season of Challenges for Those With Food Allergies 2Health News:Sexy Wedding Dresses with Special Discounts Launched by Angeldress.co.uk 2
... , WASHINGTON , Jan. 25 The American ... comprehensive health reform legislation to the president in the coming weeks. ... Executive Director Georges C. Benjamin , MD, FACP, FACEP (E), ... challenging, we cannot allow politics to derail the much needed reform ...
... , PHILADELPHIA , Jan. 25 ... common birth defects in humans, affecting 8 per 1000 ... intervention in early infancy. Increasing numbers of survivors combined ... achievement have led to a growing identification of neurobehavioral ...
... may help prevent future epidemics, , MONDAY, Jan. 25 ... genomes from three successive epidemics of flesh-eating bacteria have ... events that contribute to deadly epidemics of severe infection. ... help prevent major epidemics in the future, the American ...
... for the mind and body, series of studies finds , MONDAY, ... more evidence on the matter, along come four new studies verifying ... plan to survive to a vigorous, hardy and tough-boned old age. ... of the Archives of Internal Medicine . , "I like ...
... Jan. 25 Hylant Group, one of the ... the W Group, a privately owned firm offering employee benefit ... service and greater expertise. The combined organizations will form one ... Cincinnati area.   , The merger between the two ...
... WASHINGTON , Jan. 25 On January ... and Children voted unanimously to add screening for Severe Combined Immune ... to the core panel for universal screening of all newborns in ... affected infants lack T lymphocytes, the white blood cells that help ...
Cached Medicine News:Health News:APHA Urges Congress to Forge Ahead on Health Reform 2Health News:Special Bypass Procedure Used During Infant Heart Surgery Does Not Impair Later Neurological Outcomes in Children 2Health News:Special Bypass Procedure Used During Infant Heart Surgery Does Not Impair Later Neurological Outcomes in Children 3Health News:Scientists Find Way to Track Flesh-Eating Bacteria 2Health News:More Proof Exercise Leads to Healthier Aging 2Health News:More Proof Exercise Leads to Healthier Aging 3Health News:Two of Cincinnati's Leading Employee Benefit Providers Merge to Offer Clients Greater Expertise and Service 2Health News:Immune Deficiency Foundation Praises ACHDNC Recommendation for SCID Screening in Newborns 2Health News:Immune Deficiency Foundation Praises ACHDNC Recommendation for SCID Screening in Newborns 3Health News:Immune Deficiency Foundation Praises ACHDNC Recommendation for SCID Screening in Newborns 4
(Date:11/21/2014)... , Nov. 20, 2014 Oxis International, Inc. ... , the election of Anthony J. Cataldo as ... Effective November 19, 2014, Ken Eaton ... the Board of Directors of Oxis International, Inc. to pursue ... has been named Chief Executive Officer of Oxis International, Inc. ...
(Date:11/21/2014)... 21, 2014  Lexicon Pharmaceuticals, Inc. (Nasdaq: ... offering of $80,000,000 aggregate principal amount of 5.25% Convertible ... private offering within the United States ... buyers pursuant to Rule 144A under the Securities Act ... also granted the initial purchasers an option to purchase ...
(Date:11/18/2014)... ANGELES , Nov. 18, 2014  Sanguine ... development, patient engagement and study recruitment – will ... called Sangre, to help Pfizer Inc. find and ... (CIP) and their family members to participate in ... potentially identify DNA mutations and hopefully aid in ...
Breaking Medicine Technology:OXIS International, Inc. announces Changes in Management Team 2OXIS International, Inc. announces Changes in Management Team 3Lexicon Announces Pricing Of Convertible Senior Notes Offering 2Lexicon Announces Pricing Of Convertible Senior Notes Offering 3Sanguine's Mobile Application to Assist Recruitment for Pfizer Inc. Chronic Pain Research 2
... Results Reported at American Association for Dental Research ... Parion Sciences, Inc., a,privately-held, development-stage pharmaceutical company dedicated ... body,s mucosal,defenses, today announced preliminary results from a ... channel blocker, P-552-02, as a topical,therapy for dry ...
... April 7 A biosimilar product for,treating the ... the,white blood cells of patients is safe and ... a reference,product. This is the result of a ... company Kwizda Pharma GmbH and the Indian manufacturer,INTAS ...
Cached Medicine Technology:Parion Sciences Announces Phase I Clinical Results for Novel Dry Mouth Treatment 2Parion Sciences Announces Phase I Clinical Results for Novel Dry Mouth Treatment 3Neutropenia: Biosimilar Product from India Moves One Step Closer to European Market 2Neutropenia: Biosimilar Product from India Moves One Step Closer to European Market 3
... Innovators in Anesthesia and Respiratory Products, ... medical devices for Anesthesia and Respiratory professionals. ... products that enhance the clinician's ability to ... attention to the bottom line. , ...
... and Respiratory Products, ,Westmed designs, manufacturers ... Anesthesia and Respiratory professionals. Our mission is ... the clinician's ability to deliver quality medical ... bottom line. , ,Our web site ...
... the new PRONEB® ULTRA compressor. This high ... while delivering more medication to the patient's ... PLUS® or PARI LC STAR® Reusable Nebulizer, ... for inhalation and retention into the lungs. ...
... use with metered dose inhalers., ,ACE ... from MDI canisters. Its versatile design allows ... circuit, in conjunction with an endotracheal airway ... inhalation. ACE may also be used in ...
Medicine Products: