Navigation Links
Discovery of a novel medicine for the treatment of chronic wounds
Date:5/20/2013

Every 20 seconds, a limb is lost as a consequence of diabetic foot ulcer that does not heal. To date, medical solutions that can change this situation are very limited. In his doctoral thesis Yue Shen from the Industrial Doctoral School and the Department of Medical Biochemistry and Biophysics at Ume University presented a novel medicine for chronic wound treatment that may completely change the lives of millions of patients.

Diabetic wounds are the most severe type of chronic wounds that largely impair the quality of life in patients and inflict an enormous burden on the healthcare system. World-wide, there are more than 350 million diabetic patients and about 20% of them develop diabetic foot ulcers that often do not heal, which eventually lead to amputation. Chronic eardrum perforations are another type of chronic wounds. Today the only existing treatment of chronic eardrum perforations is through surgery.

In his thesis, Yue Shen demonstrates that plasminogen, a well-know plasma protein, acts as a key regulatory molecule of inflammation that can be used to treat different types of chronic wounds including diabetic wounds and chronic eardrum perforations. Yue Shen demonstrates that the level of plasminogen dramatically increases in and around wounds, which leads to an enhanced inflammation that is required for healing. In diabetic wounds that do not heal, the level of plasminogen does not increase and the inflammatory response is suppressed. When plasminogen is injected around diabetic wounds, the healing process starts and the wounds eventually heal fully. In chronic eardrum perforations, local injection and topical application of plasminogen also stimulates the healing and leads to complete healing.

Based on these studies, a controlled clinical study using human plasminogen to treat chronic wounds in humans is now planned. The ultimate goal is to develop plasminogen to a medicine for the treatment of various chronic wounds.


'/>"/>
Contact: Yue Shen
yue.shen@medchem.umu.se
46-722-318-699
Umea University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. MessageSolution Releases Enterprise eDiscovery Platform 7.0 at LegalTech 2013 West Coast Expo
2. Wright Conserve Hip Replacement Lawsuits Move Forward, as Bernstein Liebhard LLP Notes Issuance of Amended Discovery Plan in Federal Wright Hip Litigation
3. Transvaginal Mesh Lawsuit News: Bernstein Liebhard LLP Notes Order Reopening Discovery in Federal C.R. Bard Vaginal Mesh Litigation
4. Gene Discovery May Offer Breakthrough for Rare Leukemia
5. Immune Cell Discovery May One Day Lead to Herpes Vaccine: Study
6. The Discovery House Hosts First Alumni Meeting
7. Voices Against Brain Cancer Comments on New Discovery That May Help MDs Diagnose and Treat Certain Pediatric Brain Tumors
8. Discovery of New Cause of Congenital Hydrocephalus Opens the Door to Collaborative Research Study, Hydrocephalus Association Commends Researchers
9. Reinventing drug discovery
10. Life Sciences Discovery Fund makes grant awards to commercialize promising technologies
11. Discovery opens door to new drug options for serious diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/30/2015)... ... June 30, 2015 , ... As 1Heart ... continuing growth as a Master Franchisor. 1Heart Caregiver Services® welcomed its next Franchisee, ... of Commerce Ambassadors headed by Keith Mashburn, Pam Campeau, field representative of the ...
(Date:6/30/2015)... ... June 30, 2015 , ... In the Spring of 2015, as California ... Sierra Nevada mountains measured zero for the first time since records have been kept, ... of its most sustained periods of increasing drought.” , In response to ...
(Date:6/30/2015)... ... 2015 , ... Carey Danis & Lowe comments on a new ... Virginia federal court. The court document outlined the judge’s plan to consolidate 26 vaginal ... Carey Danis & Lowe is a personal injury law firm with headquarters in St. ...
(Date:6/30/2015)... Atlanta, GA (PRWEB) , ... June 30, 2015 , ... ... salon niche, is expanding its suite of products to mobile teeth whitening entrepreneurs. Mobile ... or hair stylists that offer convenience and a personal touch. The popularity of the ...
(Date:6/30/2015)... ... July 01, 2015 , ... Popular review ... to navigate. By making fundamental changes to the UI, the website hopes to ... said, “Finding the right website has been getting tougher. People are seeking professional ...
Breaking Medicine News(10 mins):Health News:1Heart Caregiver Services® Simi Valley Grand Opening 2Health News:1Heart Caregiver Services® Simi Valley Grand Opening 3Health News:1Heart Caregiver Services® Simi Valley Grand Opening 4Health News:RainSoil launches water-retention product as drought spreads. 2Health News:RainSoil launches water-retention product as drought spreads. 3Health News:Carey Danis & Lowe Comments on New Pretrial Order in Vaginal Mesh Lawsuit 2Health News:Carey Danis & Lowe Comments on New Pretrial Order in Vaginal Mesh Lawsuit 3Health News:White Blitz to Develop New Mobile Teeth Whitening Program for Entrepreneurs 2Health News:HerpesDatingSites.org Introduces a New Responsive Design 2
... and BEIJING, Feb. 15 /Xinhua-PRNewswire-FirstCall/ -- China,Holdings, ... diversified assets,holdings company, and its subsidiaries engage ... energy, resources, finance,real estate, utilities and pharmaceuticals, ... that it has initiated active coverage of,China ...
... of Queensland scientists have developed a proprietary technology ... of growth, development, and,disease, which has been licensed ... technology,companies., Dr Marcel Dinger and Professor John Mattick, ... new type of microarray RNA chip, used by ...
... agrees to ... Second Pharmacy in Lynn MA, BANGOR, Maine, Feb. 15 ... has acquired the remaining 20%,interest in its pharmacy chain subsidiary, D.A.W., ... minority interest,the former minority shareholders received a cash payment of $1.75 ...
... Ill., Feb. 15 The Joint,Commission today issued a ... to pay special attention to preventing accidents,and injuries that ... million MRI scans are performed each year in the ... dangers of the process,are not well known. The most ...
... Global Med Technologies(R),Inc. (OTC Bulletin Board: GLOB), ... today that the U.S. Food and Drug,Administration ... a new,blood management product produced by its ... the Company to proceed marketing the,product in ...
... masses, study finds , , FRIDAY, Feb. 15 (HealthDay News) ... of two types of hard-to-treat pediatric tumors without harming ... viral therapy, dubbed rQT3, slowed neuroblastoma and peripheral nerve ... the Feb. 15 issue of Cancer Research . ...
Cached Medicine News:Health News:China Holdings Announces Starwood Research Institute Initiates Research Coverage 2Health News:China Holdings Announces Starwood Research Institute Initiates Research Coverage 3Health News:China Holdings Announces Starwood Research Institute Initiates Research Coverage 4Health News:Queensland technology licensed by billion-dollar US company 2Health News:Nyer Medical Group Completes Acquisition of Minority Interest in Pharmacy Chain Subsidiary; Former Minority Shareholders Invest in Nyer Medical Group and Sign 3-Year Employment Agreements 2Health News:Nyer Medical Group Completes Acquisition of Minority Interest in Pharmacy Chain Subsidiary; Former Minority Shareholders Invest in Nyer Medical Group and Sign 3-Year Employment Agreements 3Health News:Joint Commission Alert Shines Light on Preventing MRI Accidents, Injuries 2Health News:Joint Commission Alert Shines Light on Preventing MRI Accidents, Injuries 3Health News:Global Med Technologies(R), Inc. Recieves FDA 510(K) Clearance for ElDorado Donor(TM) 2Health News:Global Med Technologies(R), Inc. Recieves FDA 510(K) Clearance for ElDorado Donor(TM) 3Health News:Viral Therapy Slows Pediatric Tumors in Mice 2
(Date:6/30/2015)... June 30, 2015  The MEDevice San Diego Conference, ... an event dedicated to bringing medtech professionals together for ... topics affecting the industry today. This year,s conference will ... and opportunities facing today,s medtech professional in a fun, ... register for MEDevice San Diego, please visit: MEDeviceSD.com. ...
(Date:6/30/2015)... June 30, 2015 Velos, Inc., the pioneering ... to grow and add customers who receive Clinical and ... 62 CTSAs awarded by the National Institutes of Health ... This is among the largest such market shares in ... the CTSA community keeps growing as a result of ...
(Date:6/30/2015)... Nortek Security & Control LLC, a ... a leader in the residential and commercial security ... mobile personal emergency response system (mPERS) and telehealth ... Headquartered in Seattle ... products and cloud-based software platforms that enable providers ...
Breaking Medicine Technology:MEDevice San Diego 2015 Attracts High-Tech Medical Industry 2Velos continues adding CTSA customers - 40% now use Velos products 2Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 2Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 3Nortek Security & Control Acquires Health and Wellness Technology Business from Numera 4
... Misonix, Inc. (Nasdaq: MSON ), a developer ... which worldwide is used for acute health conditions, today ... year ending June 30, 2010.  Michael A. McManus, Jr., ... VP and Chief Financial Officer, will host a conference ...
... YORK, Sept. 28 Reportlinker.com announces that a new ... Global In Vitro Diagnostics (IVD) Market Report: ... The global IVD market has been experiencing ... has been growing awareness about health and prevention of ...
Cached Medicine Technology:Misonix Reports Fourth Quarter and Fiscal Year 2010 Financial Results 2Misonix Reports Fourth Quarter and Fiscal Year 2010 Financial Results 3Misonix Reports Fourth Quarter and Fiscal Year 2010 Financial Results 4Misonix Reports Fourth Quarter and Fiscal Year 2010 Financial Results 5Misonix Reports Fourth Quarter and Fiscal Year 2010 Financial Results 6Misonix Reports Fourth Quarter and Fiscal Year 2010 Financial Results 7Misonix Reports Fourth Quarter and Fiscal Year 2010 Financial Results 8Misonix Reports Fourth Quarter and Fiscal Year 2010 Financial Results 9Reportlinker Adds Global In Vitro Diagnostics (IVD) Market Report: 2010 Edition 2Reportlinker Adds Global In Vitro Diagnostics (IVD) Market Report: 2010 Edition 3Reportlinker Adds Global In Vitro Diagnostics (IVD) Market Report: 2010 Edition 4Reportlinker Adds Global In Vitro Diagnostics (IVD) Market Report: 2010 Edition 5
Sony DVD Recorder for recording and playback of DVD video discs to complement DP micro video cameras....
... consists of 2-piece body, one is CHU (Camera ... built-in Peltier cooling devices, the other is CCU ... CCU incorporates IEEE1394 interface for direct connection with ... slot for storing images into memory stick or ...
The TRIstar II is a highly developed 3-chip video camera for endoscopic applications. Superior image quality and outstanding colour reproduction meets professional requirements....
For continuous intracranial monitoring of pressure, oxygen and temperature of the brain...
Medicine Products: