Navigation Links
Discovery of Gene May Lead to New Male Contraceptive
Date:5/24/2012

THURSDAY, May 24 (HealthDay News) -- The discovery of a key gene involved in sperm development could eventually lead to the creation of a new type of non-hormonal birth control for men, a study involving mice suggests.

Researchers found that a gene called Katnal1 is critical to enable sperm to mature in the testes. Finding a way to regulate this gene could prevent sperm from maturing, making them incapable of fertilizing eggs.

This finding also could lead to new treatments for cases of male infertility in which the Katnal1 gene malfunctions and hampers sperm development, according to the study, from researchers at the University of Edinburgh in Scotland.

The researchers found that male mice modified to lack the Katnal1 gene were infertile. Further investigation revealed that the gene was essential for sperm development and maturation.

Successful trials in mice do not necessarily mean the success will translate to humans, however.

The study was published in the journal PLoS Genetics.

"If we can find a way to target this gene in the testes, we could potentially develop a non-hormonal contraceptive," study author Lee Smith, of the University of Edinburgh's Center for Reproductive Health, said in a journal news release.

"The important thing is that the effects of such a drug would be reversible because Katnal1 only affects sperm cells in the later stages of development, so it would not hinder the early stages of sperm production and the overall ability to produce sperm," Smith said.

"Although other research is being carried out into non-hormonal male contraceptives, identification of a gene that controls sperm production in the way Katnal1 does is a unique and significant step forward in our understanding of testis biology," Smith concluded.

More information

The U.S. Department of Health and Human Services Office on Women's Health has more about birth control methods.

-- Robert Preidt

SOURCE: PLoS Genetics, news release, May 24, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Discovery suggests new combination therapy strategy for basal-like breast cancers
2. Researchers make promising discovery in pursuit of effective lymphoma treatments
3. Scientists make breakthrough in bile duct cancer with discovery of new gene mutations
4. H1N1 discovery paves way for universal flu vaccine: UBC research
5. Feelings of immaturity accompany alcohol misuse into adulthood; discovery could improve treatments
6. Discovery could help to develop drugs for organ transplant and cancer patients
7. Washingtons Life Sciences Discovery Fund awards commercialization grants
8. Scientist awarded $1 million grant to develop tools for hepatitis C treatment discovery
9. New discovery of proteins involved in positioning muscular nuclei
10. Cell signaling discovery provides new hope for blood disorders
11. Gene mutation discovery sparks hope for effective endometriosis screening
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Discovery of Gene May Lead to New Male Contraceptive
(Date:2/12/2016)... (PRWEB) , ... February 12, ... ... Foundation today announced a new initiative—the Siemens Foundation-PATH Ingenuity Fellowships—to develop the ... partnership will recruit top students from U.S. universities who will draw from ...
(Date:2/12/2016)... ... February 12, 2016 , ... Fixed Dose ... – 3:00 p.m. EST, http://www.fdanews.com/fixeddosecombination , Fixed dose ... products, garnering increased attention from all stakeholders in the development of new chemical ...
(Date:2/12/2016)... ... February 12, 2016 , ... Coco Libre, the maker ... Red Carpet Events LA GRAMMY’s Style Lounge Event. Coco Libre will offer musicians and ... hydrated before the big event. The invitation-only gifting suite, held this year at the ...
(Date:2/12/2016)... ... 12, 2016 , ... Itopia, a leader in cloud services ... Intelligence Platform (CIP) into Cielo®, a discovery, migration and cloud orchestration engine. This ... small and medium business (SMB) clients. , In recent years, BI ...
(Date:2/12/2016)... ... February 12, 2016 , ... AssureVest Insurance Group, a locally owned insurance firm ... that will raise funds earmarked to purchase computers and software for Mrs. Harrison’s 2nd ... school is in a low-income area and has more than 60 2nd and 3rd ...
Breaking Medicine News(10 mins):
(Date:2/12/2016)... , 12 februari 2016 AAIPharma ... toonaangevende leverancier van productie en ontwikkeling op ... kondigt vandaag een uitbreiding aan van steriele ... locatie in Charleston, SC ... tot meerdere recente investeringen. http://photos.prnewswire.com/prnh/20150806/256637LOGO ...
(Date:2/12/2016)... BUDAPEST , Ungarn, February 12, 2016 ... ein Medizintechnikunternehmen, das sich auf den ungedeckten ... gab heute positive Ergebnisse seines klinischen Forschungsprogramms ... und Asthma-Patienten beschäftigt, ergab Verbesserungen ihrer respiratorischen ... Indiso ltd , ein Medizintechnikunternehmen, das ...
(Date:2/11/2016)... 2016 - Cardiac Marker ... Medicine and Cancer Therapy. - European Point of ... Markets. - Key Diagnostic Testing Markets. - ... in Genetic Testing. - Molecular Diagnostics in Infectious ... Over-the-Counter Diagnostic Products World Markets. - Point of ...
Breaking Medicine Technology: