Navigation Links
Discovery May Improve Diagnosis of Alzheimer's, Parkinson's
Date:8/29/2012

WEDNESDAY, Aug. 29 (HealthDay News) -- Four indicators, or "biomarkers," found in cerebrospinal fluid can help differentiate patients with Alzheimer's disease from those with other forms of dementia, and a different biomarker can distinguish patients with Parkinson's disease from those with parkinsonian disorders, researchers say.

Overlapping symptoms, especially in the early stages, can make it difficult to distinguish between regular Parkinson's disease and atypical Parkinsonism, and also between Alzheimer's disease and other forms of dementia, the study authors explained.

The investigators identified the five biomarkers by analyzing cerebrospinal fluid samples from 453 patients with Parkinson's, Parkinson's disease with dementia, Alzheimer's and other forms of dementia.

"Together with earlier published data, our results indicate that these five [cerebrospinal fluid] biomarkers might have clinical value in the differential diagnosis of dementia and/or parkinsonism," concluded Dr. Sara Hall, of Skane University Hospital in Sweden, and colleagues.

The study was published online Aug. 27 in the journal Archives of Neurology.

The findings represent "a significant step forward, demonstrating how a relatively modest panel of robust [cerebrospinal fluid] protein biomarkers can categorize dementias and parkinsonian syndromes on the basis of pathology rather than clinical/behavioral changes," Dr. Richard Perrin, of the Washington University School of Medicine in St. Louis, wrote in an accompanying editorial.

The use of these indicators in cerebrospinal fluid could improve the efficiency of clinical trials and speed up the development and evaluation of new treatments for neurological diseases, Perrin concluded.

More information

The National Parkinson Foundation has more about atypical Parkinsonism.

-- Robert Preidt

SOURCE: Archives of Neurology, news release, Aug. 27, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. A vaccine for heart disease? La Jolla Institute discovery points up this possibility
2. SFU duos protein discovery links to cancer research
3. Life Sciences Discovery Fund makes company grants in health-related technologies
4. Evolutionary information improves discovery of mutations associated with diseases
5. Discovery improves understanding of early onset inflammatory disease
6. Discovery explains how cellular pathways converge to regulate food intake and body weight
7. New mouse model helps explain gene discovery in congenital heart disease
8. Discovery helps mice beat urinary tract infections
9. Illnesses in Colorado childrens hospital prompts discovery of contaminated alcohol pads
10. 5 more pharmaceutical companies join NIH initiative to speed therapeutic discovery
11. Discovery of Gene May Lead to New Male Contraceptive
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Discovery May Improve Diagnosis of Alzheimer's, Parkinson's 
(Date:5/5/2016)... ... May 05, 2016 , ... Qrono Inc. ... announced a development collaboration with the Australian critical medicine company, Phebra Pty ... schizophrenia. , LAI medicines can offer improved therapeutic benefits over oral formulations, including ...
(Date:5/5/2016)... ... May 05, 2016 , ... Einstein Medical is ... to cover the latest news and commentary at the 2016 ASCRS/ASOA Symposium and Congress, ... the American Society of Cataract and Refractive Surgery and the American Society of Ophthalmic ...
(Date:5/5/2016)... ... May 05, 2016 , ... This weekend, from Friday, May 6 - Sunday, May ... California terrain at the first Team Semper Fi Mountain Bike Camp, hosted in conjunction with ... mountain bike legends Mark Weir and Jason Moeschler, who’ll share pro tips with the injured ...
(Date:5/5/2016)... ... May 05, 2016 , ... ... exercises, the Wharton Seminars for Business Journalists , led by the ... key business and economic issues.  This one-day program at the Wharton School’s ...
(Date:5/5/2016)... ... ... Derrin Doty Group has unveiled the latest charity campaign in their ongoing community ... The insurance provider’s caring team has been so moved by the sudden death of ... the flu, that they have decided to extend their original campaign. Compassionate community members ...
Breaking Medicine News(10 mins):
(Date:5/3/2016)... May 3, 2016   BIOTRONIK will be ... care beyond the implant at the Heart Rhythm Society,s ... San Francisco . ... highest quality of patient care and satisfaction possible. Part ... each and every tomorrow," said Marlou Janssen , ...
(Date:5/3/2016)... Pharmaceutical giant Johnson & Johnson ... woman who says its talc-based powder products caused ovarian ... $5 million in compensatory damages and $50 million ... ) , This is the second ... February, the same court awarded $72 million to the ...
(Date:5/3/2016)... 2016  Specialty Silicone Fabricators is offering teachers ... a cleanroom works. The free visual aid provides ... technology. Chris Mazelin , ... SSF enthusiastically supports the Science, Technology, Engineering and ... next generation of innovators. We want to provide ...
Breaking Medicine Technology: