Navigation Links
Discovery May Improve Diagnosis of Alzheimer's, Parkinson's
Date:8/29/2012

WEDNESDAY, Aug. 29 (HealthDay News) -- Four indicators, or "biomarkers," found in cerebrospinal fluid can help differentiate patients with Alzheimer's disease from those with other forms of dementia, and a different biomarker can distinguish patients with Parkinson's disease from those with parkinsonian disorders, researchers say.

Overlapping symptoms, especially in the early stages, can make it difficult to distinguish between regular Parkinson's disease and atypical Parkinsonism, and also between Alzheimer's disease and other forms of dementia, the study authors explained.

The investigators identified the five biomarkers by analyzing cerebrospinal fluid samples from 453 patients with Parkinson's, Parkinson's disease with dementia, Alzheimer's and other forms of dementia.

"Together with earlier published data, our results indicate that these five [cerebrospinal fluid] biomarkers might have clinical value in the differential diagnosis of dementia and/or parkinsonism," concluded Dr. Sara Hall, of Skane University Hospital in Sweden, and colleagues.

The study was published online Aug. 27 in the journal Archives of Neurology.

The findings represent "a significant step forward, demonstrating how a relatively modest panel of robust [cerebrospinal fluid] protein biomarkers can categorize dementias and parkinsonian syndromes on the basis of pathology rather than clinical/behavioral changes," Dr. Richard Perrin, of the Washington University School of Medicine in St. Louis, wrote in an accompanying editorial.

The use of these indicators in cerebrospinal fluid could improve the efficiency of clinical trials and speed up the development and evaluation of new treatments for neurological diseases, Perrin concluded.

More information

The National Parkinson Foundation has more about atypical Parkinsonism.

-- Robert Preidt

SOURCE: Archives of Neurology, news release, Aug. 27, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. A vaccine for heart disease? La Jolla Institute discovery points up this possibility
2. SFU duos protein discovery links to cancer research
3. Life Sciences Discovery Fund makes company grants in health-related technologies
4. Evolutionary information improves discovery of mutations associated with diseases
5. Discovery improves understanding of early onset inflammatory disease
6. Discovery explains how cellular pathways converge to regulate food intake and body weight
7. New mouse model helps explain gene discovery in congenital heart disease
8. Discovery helps mice beat urinary tract infections
9. Illnesses in Colorado childrens hospital prompts discovery of contaminated alcohol pads
10. 5 more pharmaceutical companies join NIH initiative to speed therapeutic discovery
11. Discovery of Gene May Lead to New Male Contraceptive
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Discovery May Improve Diagnosis of Alzheimer's, Parkinson's 
(Date:6/26/2016)... ... June 26, 2016 , ... Many women are ... with endometriosis. These women need a treatment plan to not only alleviate symptoms ... can help for preservation of fertility and ultimately achieving a pregnancy. The specialists ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , the ... Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , “We ... new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First Choice ...
(Date:6/24/2016)... Los Angeles, CA (PRWEB) , ... June 24, 2016 , ... ... plastic surgery procedures that most people are unfamiliar with. The article goes on to ... known procedures, but also many of these less common operations such as calf and ...
(Date:6/24/2016)... ... ... Global law firm Greenberg Traurig, P.A. announced that 20 Florida attorneys are ... for this recognition are considered among the top 2 percent of lawyers practicing within ... of this year’s Legal Elite Hall of Fame: Miami Shareholders Mark D. Bloom, ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... today at the Clinical Decision Making in Emergency Medicine conference in Ponte Vedra ... authored journal articles published in Emergency Medicine Practice and Pediatric Emergency ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... Story Highlights: ... the health care industry is causing providers to review ... Deloitte offers a suite of solutions for health care ... cost optimization: labor resource analysis, revenue cycle optimization and ... outcomes and better economics ...
(Date:6/24/2016)... June 24, 2016 ... announced the addition of the " Global Markets ... This report focuses ... an updated review, including its applications in various applications. ... market, which includes three main industries: pharmaceutical and biotechnology, ...
(Date:6/24/2016)... -- Research and Markets has announced the addition ... report to their offering. ... The World Market for Companion Diagnostics covers the world ... in the report includes the following: , ... by Region (N. America, EU, ROW), 2015-2020 , World ...
Breaking Medicine Technology: