Navigation Links
Discovery Boosts Boys' Prospects for Post-Cancer Fertility
Date:11/20/2009

Testicular cells could be preserved for later use, study suggests

FRIDAY, Nov. 20 (HealthDay News) -- New research suggests it may become possible for pre-pubescent boys stricken by cancer to prepare for the future when they may be infertile but still want to become natural fathers.

Scientists in the Netherlands found that testicular stem cells can be cultured and multiplied, potentially creating sperm. This raises the prospect that men made infertile by childhood cancer treatments could impregnate women by having the cells implanted in their testicles.

It may take some time to figure out how to make this process work. But a delay may not be a problem, said study co-author Ans van Pelt, since "it may easily take more than 10 years before a boy diagnosed with cancer today has a wish to have his own child."

Currently, there's no way for a boy who hasn't reached puberty to produce sperm and save it for a future time when he wants to become a natural father. Chemotherapy, in particular, can cause infertility in boys.

Van Pelt, a fertility researcher at the University of Amsterdam, and colleagues took stem cells from the testicles of six patients during prostate cancer surgery. They then tried to coax the cells to multiply.

The findings are published in the Nov. 18 issue of the Journal of the American Medical Association.

The researchers succeeded, and the stem cells, which form sperm, multiplied.

There are caveats. The cells came from adult men, not boys who haven't reached puberty. Researchers don't know if the cells can create sperm in humans. And it's possible that the cells could transmit cancer to the recipients, so researchers will have to figure out how to prevent that possibility.

Also, the costs are unclear. It may not be expensive to remove testicular tissue and store it, but work in the laboratory and transplantation into a patient could cost more, van Pelt said.

Still, van Pelt said, "this is a big step forward."

But would parents and boys undergoing chemotherapy even be thinking a decade or more ahead, especially while dealing with the strain of cancer itself?

"Yes, since the parents of these boys are very much concerned about the future fertility of their son," van Pelt said. "We have investigated this already, and found that over 60 percent of parents would want to store testicular tissue of their son."

Dr. Jill P. Ginsberg, director of the Cancer Survivorship Program at Children's Hospital of Philadelphia, said that parents of these children do indeed look forward. "Fertility is an important part of any survivor's quality of life, and families are able to understand this even at the time of diagnosis, which is incredibly stressful," she said.

More information

Learn more about childhood cancer from the Nemours Foundation.



SOURCES: Ans van Pelt, Ph.D., fertility researcher, University of Amsterdam, the Netherlands; Jill P. Ginsberg, M.D., director, Cancer Survivorship Program, Children's Hospital of Philadelphia; Nov. 18, 2009, Journal of the American Medical Association


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. SENSA(R) WEIGHT-LOSS PROGRAM: The Accidental Discovery Thats Transforming The Way People Lose Weight Breaks the Top 500 at Amazon.com in Less Than Two Weeks of Publication
2. Gene Discovery Gives Clues to Crohns Disease, Colitis
3. VIA Pharmaceuticals Featured at Cambridge Healthtech Institute Discovery on Target 2009 Conference
4. NIAID announces vaccine adjuvant discovery contracts
5. Jan Dr. G Garavaglia Examines Shocking Cases That Shook the Forensic World in an All-New Discovery Health Special
6. Gene Discovery May Advance Head and Neck Cancer Therapy
7. Boston Biotech R&D Conference to Showcase Next-Generation Newsmakers and Massachusetts as Leader in Biotech Discovery
8. Discovery could improve hepatitis C treatment
9. Discoverys Edge Fall Issue -- http://discoverysedge.mayo.edu/
10. 3rd Annual Collaborative Drug Discovery - UCSF Community Meeting for Catalyzing Humanitarian and Commercial Research to be Held October 1st
11. Discovery May Pave Way to Better Diabetes Care
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/23/2017)... ... February 23, 2017 , ... The Lymphoma Research ... lymphoma research and serving the lymphoma community through a comprehensive series of education ... Country Club in Miami Beach to host its Swirl: Miami Wine Tasting Event ...
(Date:2/23/2017)... ... February 23, 2017 , ... The American Cleft Palate-Craniofacial Association ... Annual Meeting. KLS is a longtime supporter of the event. , "We are ... Platinum Sponsor," said Dr. Bob Havlik, 2017 ACPA President. "KLS Martin has a long ...
(Date:2/23/2017)... ... February 23, 2017 , ... Hamlin Dental Group and Dr. Hamid ... sponsoring a raffle. Throughout the month of February, patients who visit Hamlin Dental Group ... for a dinner for two at the Cheesecake Factory. , Tickets are available ...
(Date:2/23/2017)... ... 23, 2017 , ... EBSCO Information Services (EBSCO) ... for Health and Care Excellence (NICE) framework. The agreement allows purchasers from ... to search, order and purchase medical and healthcare-related content through GOBI ®, ...
(Date:2/23/2017)... ... February 23, 2017 , ... Dr. David Mahon leads Siena Dental, a ... Mahon was named a 2017 Top Patient Rated Henderson Dentist by Find ... that recognizes local physicians and dentists who have earned high ratings and superior patient ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... BRISBANE, Australia , Feb. 23, 2017  Directors from Pharma ... the two companies have joined forces, resulting in the founding of ... . Pharma To Market are pleased to announce their ... an office in Singapore . The company are ... Consulting as Co-Director of the Singapore based ...
(Date:2/24/2017)... Feb 24, 2017 Medivir AB ... for a new Board of Directors that will be ... Nomination Committee comprises representatives of the company,s three largest ... 2016 who have accepted a seat on the Nomination ... of the 2016-2017 Nomination Committee was as follows:  ...
(Date:2/23/2017)... Research and Markets has announced the addition of the "Autism ... to their offering. ... The latest research Autism Spectrum Disorder Drugs Price Analysis and ... global Autism Spectrum Disorder market. The research answers the following ... marketed for Autism Spectrum Disorder and their clinical attributes? How are ...
Breaking Medicine Technology: