Navigation Links
Discovered a new way to control genetic material altered in cancer
Date:6/5/2014

When we talk about genetic material, we are usually referring to the DNA (deoxyribonucleic acid) that we inherit from our parents. This DNA is the factory where is built a similar molecule called RNA (ribonucleic acid) which produces our proteins, such as hemoglobin or insulin , allowing the lives of our cells. But there is a special group called non-coding RNA that has a more enigmatic function.

The best known is microRNAs, tiny molecules that are responsible for turning on or off our genome like an electrical current switch. Today, an article published in the prestigious journal Molecular Cell by Manel Esteller, Director of Epigenetics and Cancer Biology Program of the Bellvitge Biomedical Research Institute (IDIBELL), ICREA researcher and Professor of Genetics at the University of Barcelona, provides a twist over this mystery.

Research shows that there is a second type of non-coding RNA, called ultra-conserved RNA that acts as switches switch, ie , controls the activity of microRNAs.

"Who watches the watchers? This was one of the issues that we set at the beginning of the research" says Esteller. "We have found that special molecules called ultra-conserved RNA were not produced in human tumors and this contributed to their growth, but we knew nothing about this mechanism. It should be an important role because these molecules are highly conserved in evolution and there is no variation from chickens to humans. We realized ultraconservated RNAs attached to the other family of non-coding RNAs , microRNAs, as a magnet and prevented its function. That is, they are the police internal affairs officers who supervise the battle soldiers in healthy cells . If a cell fails to produce the ultraconservated RNA, microRNA gets altered and hundreds of genes that should maintain cellular balance does and thus contributes to the formation of human tumors, " concludes Manel Esteller.

The results obtained by the group Esteller i
'/>"/>

Contact: Arantxa Mena
amena@idibell.cat
34-932-607-282
IDIBELL-Bellvitge Biomedical Research Institute
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. New method discovered to protect against chemical weapons
2. Finnish researchers discovered a new anticancer compound
3. Extinct kitten-sized hunter discovered
4. Novel therapeutic agent for Tamiflu-resistant pH1N1 influenza virus discovered
5. First genetic link discovered to difficult-to-diagnose breast cancer sub-type
6. New pain relief targets discovered
7. Brainstem discovered as important relay site after stroke
8. Critical protein discovered for healthy cell growth in mammals
9. Molecule discovered that protects the brain from cannabis intoxication
10. CU researchers may have discovered a plan to disable Menieres disease
11. Newly discovered brown fat cells hold possibilities for treating diabetes, obesity
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Discovered a new way to control genetic material altered in cancer
(Date:9/19/2014)... On September 16, Camino Public Relations ... and Top Places to Work in PR Awards Luncheon ... received honorable mentions in two categories for “Multicultural Campaign” ... elevating Latina voices in the media. , "We're honored ... part of its efforts to improve the national conversation ...
(Date:9/19/2014)... NY (PRWEB) September 19, 2014 According ... manufacturers of the embattled blood-thinner Xarelto, named as defendants ... of Common Pleas, have moved the court to dismiss ... do not have sufficient connection with Philadelphia.* The cases ... et al. (No. 140304328; Pa. Comm. Pls., Philadelphia Cty.), ...
(Date:9/19/2014)... 19, 2014 (HealthDay News) -- Although there is ... benefits, most middle-aged and older adults in the ... exercise, according to new research. Less than ... recommendations set by the Department of Health and ... is essential for promoting health and fitness and ...
(Date:9/19/2014)... (PRWEB) September 19, 2014 MetroMD, a leading ... the “God Particle” of human health. This therapy has grown ... making the therapy more effective, safe and dependable. It has ... them an opportunity to live a very healthy and active ... concept of HGH therapy, a senior therapist at MetroMD said, ...
(Date:9/19/2014)... Domestic violence occurs at least as frequently, and ... to opposite-sex couples, according to a review of ... Previous studies, when analyzed together, indicate that domestic ... lesbian, gay and bisexual individuals. However, a lack ... an incomplete picture of the true landscape, suggesting ...
Breaking Medicine News(10 mins):Health News:Camino Public Relations Honored for Raising Latina Voices in National Health Care, Immigration Debates 2Health News:Xarelto Makers Seek Dismissal of Cases Brought in Philadelphia, Notes Rottenstein Law Group LLP 2Health News:Xarelto Makers Seek Dismissal of Cases Brought in Philadelphia, Notes Rottenstein Law Group LLP 3Health News:Adults Over 45 Not Meeting U.S. Muscle Strengthening Guidelines, Study Says 2Health News:MetroMD Announces Better HGH Therapy - the ‘God Particle’ of Human Health 2Health News:Domestic violence likely more frequent for same-sex couples 2
... Mercedes Walton, CEO of Cryo-Cell International, one of the ... progress to date and encouraging continued momentum for existing bills through ... Cord Blood Banking Act," and H.R. 2107, the "Cord Blood Education ... progress from the first half of the year to enable and ...
... Sociological Association,s 104th annual meeting, will be the subject ... present research and explore the politics, history, health and ... More than 5,000 sociologists will convene in the ... New Politics of Community," the meeting,s theme. In addition ...
... , SAN DIEGO, July 6 ADVENTRX Pharmaceuticals, Inc. ... it has completed the previously announced sale of shares ... to a registered direct offering to a single institutional ... percent, or approximately $340,250, of the gross proceeds will ...
... showed muscle fiber damage even after halting drugs, researchers say ... used to lower cholesterol, may cause structural damage to the ... study has found. , The damage may occur even when ... and may persist even after statin use is halted, according ...
... Eli Lilly and Company (NYSE: LLY ) will ... Wednesday, July 22, 2009. Lilly will also conduct a conference ... further detail the company,s financial performance. , , The ... EDT. Investors, media and the general public can access a ...
... Inc. (Nasdaq: SLTM ), a global leader in ... an amendment with Silicon Valley Bank, a member company of ... the company,s credit facility has been expanded from $9 million ... the secured revolving loan facility to $8.0 million, an amendment ...
Cached Medicine News:Health News:Stem Cell Industry Expert Praises, Encourages Continued Progress on Legislation to Promote Benefits of Cord Blood 2Health News:Stem Cell Industry Expert Praises, Encourages Continued Progress on Legislation to Promote Benefits of Cord Blood 3Health News:Sociologists to turn the sociological eye on San Francisco 2Health News:ADVENTRX Pharmaceuticals Announces Closing of Financing 2Health News:ADVENTRX Pharmaceuticals Announces Closing of Financing 3Health News:ADVENTRX Pharmaceuticals Announces Closing of Financing 4Health News:Statins May Cause Muscle Damage in Some Patients 2Health News:Statins May Cause Muscle Damage in Some Patients 3Health News:Solta Medical, Inc. Signs Amendment to Expand Its Credit Facility With Silicon Valley Bank 2Health News:Solta Medical, Inc. Signs Amendment to Expand Its Credit Facility With Silicon Valley Bank 3
(Date:9/19/2014)... , Sept. 19, 2014 Merck (NYSE: ... and Canada , is teaming with ... La Diabetes: Logra Tus Metas , an educational program encouraging Hispanics ... sugar -- a key treatment goal to help reduce the risk ... are at a higher risk for developing type 2 ...
(Date:9/19/2014)... Five MinuteClinic walk-in medical clinics are opening inside select ... Three clinics opened in Memphis and ... be added in Springfield on September 24 ... expected to open October 22.  MinuteClinic is the largest and fastest ... States . The Memphis -area ...
(Date:9/19/2014)... EASTON, Mass. , Sept. 19, 2014 /PRNewswire/ ... "Company") today announced it has received and approved ... Barozyme HT48 instruments and has begun to manufacture ... the first instrument will be ready for shipment ... be built and released at a rate of ...
Breaking Medicine Technology:Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 2Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 3Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 4Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 5MinuteClinic Walk-in Medical Clinics Opening in Memphis 2MinuteClinic Walk-in Medical Clinics Opening in Memphis 3Pressure BioSciences Announces Completion of the First Phase of Its Commercialization Plan for the Barozyme HT48, the Company's Recently Released High Throughput PCT-based Instrument System 2Pressure BioSciences Announces Completion of the First Phase of Its Commercialization Plan for the Barozyme HT48, the Company's Recently Released High Throughput PCT-based Instrument System 3
... IDEV Technologies, Incorporated (IDEV), an innovative leader in ... technologies, today announced the release of two-year European ... patients treated with the SUPERA wire interwoven nitinol ... biliary and peripheral vascular use in Europe.  In ...
... 26, 2011 The Global Coalition on Aging announced ... raise awareness and address the social and economic impact ... of America Merrill Lynch, Galderma, Intel, Johnson & Johnson, ... LLP is serving as an advisory member. ...
Cached Medicine Technology:Long-Term European Data Released for SUPERA® Stent from IDEV Technologies 2Long-Term European Data Released for SUPERA® Stent from IDEV Technologies 3Long-Term European Data Released for SUPERA® Stent from IDEV Technologies 4'Global Coalition on Aging' Launches as 450 Million People Turn 65 Over Next Two Decades 2'Global Coalition on Aging' Launches as 450 Million People Turn 65 Over Next Two Decades 3
... process makes use of ... magnetic responsiveness. The superparamagnetic ... rigid core structure ensures ... occurs upon removal of ...
Streptavidin A-Beads are polydisperse 1.8 m paramagnetic particles covalently coupled with streptavidin. The paramagnetic particles remain in solution over extended periods of time. Mixing is require...
Streptavidin MicroBeads are used for the indirect magnetic labeling and separation of cells, subcellular material, or bacteria labeled with a biotinylated primary antibody or ligand....
... beads are 1 m ... to a form of ... be useful as ligands ... mRNA isolation and the ...
Medicine Products: