Navigation Links
Dirt prevents allergy
Date:11/2/2011

Oversensitivity diseases, or allergies, now affect 25 per cent of the population of Denmark. The figure has been on the increase in recent decades and now researchers at the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), University of Copenhagen, are at last able to partly explain the reasons.

"In our study of over 400 children we observed a direct link between the number of different bacteria in their rectums and the risk of development of allergic disease later in life," says Professor Hans Bisgaard, consultant at Gentofte Hospital, head of the Copenhagen Prospective Studies on Asthma in Childhood, and professor of children's diseases at the Faculty of Health Sciences, University of Copenhagen.

"Reduced diversity of the intestinal microbiota during infancy was associated with increased risk of allergic disease at school age, he continues. But if there was considerable diversity, the risk was reduced, and the greater the variation, the lower the risk.

"So it makes a difference if the baby is born vaginally, encountering the first bacteria from its mother's rectum, or by caesarean section, which exposes the new-born baby to a completely different, reduced variety of bacteria. This may be why far more children born by caesarean section develop allergies."

In the womb and during the first six months of life, the mother's immune defences protect the infant. Bacteria flora in infants are therefore probably affected by any antibiotics the mother has taken and any artificial substances she has been exposed to.

"I must emphasise that there is not one single allergy bacteria," Professor Bisgaard points out.

"We have studied staphylococci and coli bacteria thoroughly, and there is no relation. What matters is to encounter a large number of different bacteria early in life when the immune system is developing and 'learning'. The window during which the infant is immunologically immature and can be influenced by bacteria is brief, and closes a few months after birth.

"Our new findings match the large number of discoveries we have also made in the fields of asthma and hay fever," Professor Bisgaard explains. Like allergies, they are triggered by various factors early in life.

The researchers gathered their data from a unique material consisting of 411 children whose mothers have asthma. This cohort was monitored, interviewed and tested continually from when the children were born 12 years ago, and the COPSAC group has published articles at regular intervals with new knowledge about allergy and asthma ever since.

Professor Bisgaard acknowledges the irony of something that used to be perceived as a threat to public health, namely bacteria, now turning out to be a fundamental part of a healthy life. He also points out that there may be other couplings, such as between intestinal flora and diabetes or obesity and other lifestyle diseases affecting modern man in the West.

"I think that a mechanism that affects the immune system will affect more than just allergies, he concludes. It would surprise me if diseases such as obesity and diabetes are not also laid down very early in life and depend on how our immune defences are primed by encountering the bacterial cultures surrounding us."


'/>"/>

Contact: Hans Bisgaard
bisgaard@copsac.dk
01-145-397-77363
University of Copenhagen
Source:Eurekalert

Related medicine news :

1. DTWI's Travel Carbon Monoxide Detector Prevents Carbon Monoxide Poisoning Whilst Holidaying Abroad, or in the UK
2. Whisker stimulation prevents strokes in rats, UCI study finds
3. Postpartum intervention/support prevents smoking relapse, extends breastfeeding duration
4. Gene identified that prevents stem cells from turning cancerous
5. Removing 2mm around breast cancer tumors prevents residual disease in 98 percent of patients
6. Chemotherapy plus radiation prevents bladder cancer recurrences
7. Asthma drug prevents spread of breast cancer: study
8. Gene therapy prevents memory problems in mice with Alzheimers disease
9. New discovery prevents symptoms of rare genetic disorder
10. Researchers establish new rule to predict risk of stroke, death from surgery that prevents it
11. Finnish researchers find a compound that prevents the growth of prostate cancer cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/17/2017)... ... 2017 , ... Peoples Health is pleased to announce that ... 1, 2016. Peoples Health, a Metairie-based Medicare Advantage company, serves more than 55,000 ... our provider network, and the addition will benefit our members in the Greater ...
(Date:1/17/2017)... NJ (PRWEB) , ... January 17, 2017 , ... Neil ... and financial planning assistance to communities throughout the region, is launching a charity drive ... Heart disease is by far the deadliest killer in America, and is responsible for ...
(Date:1/17/2017)... ... January 17, 2017 , ... Seceon ... cyber threats in real-time, today announced a strategic partnership with TechLab Security, ... Joining other Seceon partners, TechLab Security has become a strategic partner and a ...
(Date:1/17/2017)... CA (PRWEB) , ... January 17, 2017 , ... Many people make New Year’s resolutions ... Robert Mondavi is making it easier for people who want to kick off ... both new and existing patients. , These special offers include: , ...
(Date:1/16/2017)... ... January 17, 2017 , ... Recently, patients and staff ... Michigan, joined other volunteers and organizations in support of the annual Binder Park Zoo ... families dressed up in colorful costumes of all designs coming out to enjoy games, ...
Breaking Medicine News(10 mins):
(Date:1/17/2017)... 2017  From the company that brought a full line of ... comes a new line of companion animal pet first aid kits.  ... equine first aid, has developed two sizes of small pet first ... Inc. Featuring a small and a large companion pet ... family, is not a newcomer to working with small animals either. ...
(Date:1/17/2017)... YORK , Jan. 17, 2016  Attorney Advertising -- ... behalf of purchasers of Anthera Pharmaceuticals, Inc. ("Anthera" or the ... to obtain additional information and assist the investigation by visiting ... concerns whether Anthera and certain of its officers and/or directors ... Act of 1934. ...
(Date:1/17/2017)... -- Research and Markets has announced the addition of ... (Captive, Merchant), Synthesis (Synthetic, Biotech), Product (mAb, Hormone) Drug (OTC, Rx), ... report to their offering. ... The global active pharmaceutical ingredients market is expected to ... 2016, growing at a CAGR of 6.3% from 2016 to 2021. ...
Breaking Medicine Technology: