Navigation Links
Director of Women's Guild Lung Institute awarded grant to study treatment for lung disease
Date:2/6/2014

LOS ANGELES (Feb. 6, 2014) A Cedars-Sinai research team led by Paul W. Noble, MD, chair of the Department of Medicine and director of the Women's Guild Lung Institute, has been awarded $628,816 by California's stem cell agency to develop a treatment for idiopathic pulmonary fibrosis, a deadly disease that destroys the lungs and damages other vital organs.

The illness, which has no cure and few effective treatments, thickens and hardens lung tissue, leaving the organs badly scarred. Patients with idiopathic pulmonary fibrosis have great difficulty breathing and the chronic reduction in oxygen damages vital organs. The cause of the disease is not clearly understood and many people live only three to five years after diagnosis.

"Lung fibrosis occurs when the lung is unable to repair itself properly after injury or infection," said Noble. "Some people are more susceptible to developing fibrosis, and we currently don't understand why the normal repair and renewal of lung cells stops occurring in these patients."

The two-year study will build upon preliminary research completed at Cedars-Sinai by Noble and physician researcher Dianhua Jiang, MD, PhD. They uncovered important clues to the precise way normal lung stem cell repair occurs and how a cure might be developed.

"Currently, there is no therapy for idiopathic pulmonary fibrosis approved by the Food and Drug Administration. The only effective therapy is lung transplantation, which we do here at Cedars-Sinai," said Noble. "But if successful, our research will result in a completely novel approach to the treatment of lung diseases, allowing for the renewal and repair of the patient's cells."

This phase of Noble's research will involve the study of laboratory mice and human tissue to further identify the exact mechanisms necessary for stem cells to repair damage to the lungs.

"Funding these awards highlights our commitment to advancing the field with the most cutting-edge approaches and to help deepen our understanding of every aspect of stem cells, to help us find new treatments, and even cures for the deadliest diseases," said Jonathan Thomas, PhD, JD, chair of the governing Board of the California Institute for Regenerative Medicine.

"This award is a reflection of the highest peer recognition of Dr. Noble's scholarly efforts to discover novel approaches for understanding pathogenesis and new therapies for lung disorders," said Shlomo Melmed, MD, senior vice president for academic affairs, dean of the medical faculty and the Helene A. and Philip E. Hixon Chair in Investigative Medicine.


'/>"/>

Contact: Laura Coverson
laura.coverson@cshs.org
310-423-5215
Cedars-Sinai Medical Center
Source:Eurekalert

Related medicine news :

1. B2B e Trader is Addressing the Critical Needs of Local Businesses by Lauching the New Shop Small Business Directory
2. Sites, LLC Announces the Celebration of Green Van Dyck: Director of Sales and Internet Marketing
3. CFO 911 Solutions' Charles K. Dargan II, CEO, and Reid Dabney, Managing Director Have Been Added to the Financial Entrepreneur Platform ("FEP") of Merriman Capital, Inc., a Wholly Owned Subsidiary of Merriman Holdings, Inc. (OTCQX: MERR)
4. Jon Hoffenberg Named to the Board of Directors for Friends of Miami-Dade Public Library
5. Eagle Village Appoints Mike Mischley and Dani Montini to Board of Directors
6. Physician Director of ICU Honored for Innovative Telemedicine Program at Healdsburg District Hospital
7. Bridges to Recovery Reaches Ten-Year Milestone as Premiere, Licensed Residential Behavioral Treatment Program and Honors Founding Medical Director Dr. Terry V. Eagan
8. Dr. Marcelo Lancman, Medical Director of the Northeast Regional Epilepsy Group (NEREG) of New York and New Jersey Authors Book on New Epilepsy for Patients and Loved Ones
9. Worldwide Power Products Launches Agent Program to Reach International Customers; Hires Director of Latin American Operations
10. Expert in IVD Software joins Visiopharm’s Board of Directors
11. Medical Service Bureau (MSB) takes Next Step in Growth Initiative, Hires Director of Business Development
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... (PRWEB) , ... February 24, 2017 , ... The International ... 7th annual “Imagine Me Beyond What You See” body image mannequin art competition. Selected ... will be showcased and the winner revealed at the 31st annual iaedp Symposium, March ...
(Date:2/24/2017)... ... February 24, 2017 , ... Castle Farms, ... their Military Wedding Giveaway, with the winning couple announced on Feb. 14, 2017, ... generously donated from local vendors: A Matter of Taste, Ryan Rousseau Enterprises, A ...
(Date:2/23/2017)... ... February 23, 2017 , ... Rare Disease Report®, which ... participating in Rare Disease Day events, hosted by the Rare Disease Legislative Advocates ... a website, weekly e-newsletter and quarterly publication, will be conducting interviews with patients ...
(Date:2/23/2017)... ... 23, 2017 , ... EBSCO Information Services (EBSCO) ... for Health and Care Excellence (NICE) framework. The agreement allows purchasers from ... to search, order and purchase medical and healthcare-related content through GOBI ®, ...
(Date:2/23/2017)... ... February 23, 2017 , ... ... today that it will soon begin franchising throughout the U.S. starting this spring. ... help bring the practice of meditation mainstream. Current Meditation will be the first ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... 24, 2017 Research and Markets has announced the ... report to their offering. ... The latest research Hemophilia Drugs Price Analysis and Strategies - 2016, ... The research answers the following questions: What ... are they positioned in the Global Hemophilia market? What ...
(Date:2/24/2017)... HARRISBURG, Pa. , Feb. 24, 2017 ... Secretary of Drug and Alcohol Programs Jennifer Smith ... role in providing training for and using naloxone, a ... Mark McCullough , a recovery specialist and overdose ... naloxone by EMS providers. "A significant part ...
(Date:2/24/2017)... N.C. , Feb. 24, 2017 ... exploring ways to increase their self-service capabilities to ... Care Providers (HCPs). New research from ... pharma organizations have developed self-service website portals where ... This is just one of many findings to ...
Breaking Medicine Technology: