Navigation Links
'Difficult-to-treat asthma' may be due to difficult-to-treat patients
Date:10/22/2009

Difficult-to-treat asthma often may have more to do with patients who do not take their medication as instructed than ineffective medication, according to researchers in Northern Ireland.

"[A] significant proportion of patients with difficult asthma are poorly adherent to inhaled and oral corticosteroid therapy," wrote principal investigator, Dr. Liam Heaney, of Belfast City Hospital.

The results of the study were published in the November 1 issue of the American Journal of Respiratory and Critical Care Medicine, an official publication of the American Thoracic Society.

"Defining the scale and identifying non-adherence in this population is important given currently available and other imminent expensive biological therapies," said Dr. Heaney.

Dr. Heaney and colleagues obtained data from almost 200 patients who were referred to a tertiary referral clinic that specializes in treating difficult asthma. To assess compliance with inhaled corticosteroid therapy (ICT), they compared patient prescription to the patient's actual refill usage. They used blood plasma prednisolone and cortisol levels to evaluate oral medication adherence.

Of the 182 consecutive patients, 35 percent filled fewer than half of their prescribed inhaled combination therapy (ICT), 21 percent filled more than they were prescribed and 45 percent filled between half and all of the medication they were prescribed.

Furthermore, in patients who were on a maintenance course of oral prednisolone, blood levels of cortisol and prednisolone showed that nearly half (45 percent) were not taking the medication as prescribed. In follow-up conversations with the researchers, most admitted that they were inconsistent in the use of their medications. Of the 23 patients who were non-adherent to their oral prednisolone, 15or 65 percentwere also non-adherent to their ICT.

"All subjects had initially denied poor medication adherence, and poor
'/>"/>

Contact: Keely Savoie
ksavoie@thoracic.org
212-305-8620
American Thoracic Society
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. For Erectile Dysfunction, Physicians Indicate That Opportunity Exists for Emerging Therapies with Improved Efficacy in Difficult-to-Treat Patient Subpopulations
2. Austin, Texas, Physicians Second in Nation to Perform New Procedure for Difficult-to-Treat Atrial Fibrillation Cases
3. Novel Treatments Demonstrate Improvements in Overall Survival and Response Rates in Difficult-To-Treat Forms of Leukemia and Lymphoma
4. New chemotherapy regimen prolongs survival in difficult-to-treat childhood brainstem gliomas
5. Pediatricians put proven treatment strategies to work against childhood asthma
6. Parenting Expert and Family Advocate Jo Frost and Allergy & Asthma Network Mothers of Asthmatics (AANMA) Launch Time 2 Talk Asthma
7. Rising Heat, Humidity Raise Risk of Asthma Flares
8. $450,000 Awarded for Innovative Asthma Research Into Death by Drowning in Mucus
9. Study Demonstrates That QVAR(R) is More Cost-Effective Than Other Inhaled Corticosteroid (ICS) Asthma Therapy Options
10. Chlorine in Pools Raises Kids Asthma, Allergy Risk
11. Day Care May Not Shield Kids From Asthma, Allergies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... supports a growing body of research suggesting a ... in treating postmenopausal breast cancer, with fewer detrimental ... standard anti-hormone therapies. The study will be published ... Reproductive Biology and Endocrinology . , Breast ... women in the United States. Approximately 70% of ...
(Date:7/23/2014)... Global Cardio Care, Inc., a management company ... is celebrating the 100th birthday of Albert Weber, ... center. , Weber has been plagued with angina ... therapy since 1999, he no longer suffers from either ... Cardio Care, introduced the Sara Soulati Health For ...
(Date:7/23/2014)... The voice on the recording was low and calm as ... was infected with the human immunodeficiency virus (HIV) that causes AIDS: ... you know I was on the floor flat on my face ... when the recording ended less than 10 minutes later. “Don’t feel ... because it is just God setting you up for something greater,” ...
(Date:7/23/2014)... For patients infected with both HIV and hepatitis C, ... a small study suggests. Researchers said doctors could ... with the two diseases. "The findings suggest ... role in the management of individuals with [hepatitis C] ... a professor of medicine at the University of Cincinnati ...
(Date:7/23/2014)... Texas Physical Therapy Specialists (TexPTS) is ... Westlake, Westgate, Liberty Hill, Parmer, Balcones, and Georgetown clinics ... Orthopaedic Certified Specialist (OCS) or Sports ... DPT, OCS, Tony Lauretta, PT, DPT, OCS, Jason Brown, ... Leech, PT, DPT, OCS, and Mary Grimberg, PT, DPT, ...
Breaking Medicine News(10 mins):Health News:Hormones after breast cancer: Not fuel for the fire after all? 2Health News:Hormones after breast cancer: Not fuel for the fire after all? 3Health News:Hormones after breast cancer: Not fuel for the fire after all? 4Health News:Hormones after breast cancer: Not fuel for the fire after all? 5Health News:Global Cardio Care Celebrates EECP Patient’s 100th Birthday 2Health News:HIV clinic-based audio project emphasizes the power of patient voices 2Health News:HIV clinic-based audio project emphasizes the power of patient voices 3Health News:HIV Meds May Also Help Control Hepatitis C, Study Finds 2Health News:Texas Physical Therapy Specialists Congratulates New Board Certified Specialists 2Health News:Texas Physical Therapy Specialists Congratulates New Board Certified Specialists 3
... urge more awareness that long-term use has consequences , ... and other cardiovascular problems appear to be more common ... androgen deprivation therapy, which reduces or eliminates the male ... study has found. , The finding indicates that androgen ...
... Tamiflu Oral Suspension ... ... (SIX: RO, ROG; OTCQX: RHHBY) announced today that it has begun shipping additional quantities of ... begin arriving in pharmacies nationwide and will continue to roll out to wholesale and retail ...
... The following is an op-ed written by Fredette West, Director, African ... how can the nation can pay for health reform; and in ... all the talk about finding "off-sets" -- media, legislators, and analysts, ... studies from Johns Hopkins University and the University of Maryland. A ...
... Initiates Training Program Partnering with Healthcare Employers , WEST ... a $134,790 grant by the State of Florida to fund ... for skilled health care workers in Palm Beach County. ... Healthcare Workforce Initiative. The funding enables Workforce Alliance to ...
... can,t teach an old dog new tricks," it,s often said. ... to be passed down from generation to generation. , "While some ... them and act on them," says Mark Nunez, DVM, president of ... veterinarian to find out if a commonly held belief is really ...
... ― Two medications approved as treatment for drug-resistant chronic ... responses as a first treatment than the existing front-line ... Anderson Cancer Center reported at the 51st Annual Meeting ... for CML remains imatinib, a Novartis drug known as ...
Cached Medicine News:Health News:Prostate Hormone Therapy May Up Heart Risks 2Health News:Prostate Hormone Therapy May Up Heart Risks 3Health News:Roche Announces Shipments of New Supplies of Children's Tamiflu in the U.S. 2Health News:Roche Announces Shipments of New Supplies of Children's Tamiflu in the U.S. 3Health News:Roche Announces Shipments of New Supplies of Children's Tamiflu in the U.S. 4Health News:Roche Announces Shipments of New Supplies of Children's Tamiflu in the U.S. 5Health News:Health Reform is About You and Me, Not One or the Other 2Health News:Health Reform is About You and Me, Not One or the Other 3Health News:Workforce Alliance Earns Grant to Train Health Care Workers 2Health News:Workforce Alliance Earns Grant to Train Health Care Workers 3Health News:Some Myths About Dogs and Cats Are Not Only False - They're Dangerous! 2Health News:Second-line CML drugs evoke faster response than front-line therapy 2
(Date:7/23/2014)... 2014  Nearly 8,000 attendees will converge in ... Retail Business Conference (RBC), taking place July 23-26 at ... event encourages pharmacists to "Lead Change" in the pharmacy ... for their future. "RBC is the ... their peers and learn new ways they can lead ...
(Date:7/23/2014)... CITY, Calif. , July 23, 2014  Cardica, Inc. ... release financial results for its fiscal fourth quarter and year ... the markets close. Cardica,s management will host a conference call ... and provide an update on the company,s business. ... August 7, 2014, at 4:30 p.m. Eastern Time via phone, ...
(Date:7/23/2014)... NEW YORK , July 23, 2014  Dompe, a ... of rare diseases, announces that rhNGF (Recombinant Human Nerve Growth ... American Food and Drug Administration (FDA). The ... designated as an orphan drug for the treatment of neurotrophic ... in 5,000 people 1 and is currently without a ...
Breaking Medicine Technology:Cardinal Health Encourages Independent Pharmacists to Lead Change at 24th Annual Retail Business Conference 2Cardinal Health Encourages Independent Pharmacists to Lead Change at 24th Annual Retail Business Conference 3Cardinal Health Encourages Independent Pharmacists to Lead Change at 24th Annual Retail Business Conference 4Cardinal Health Encourages Independent Pharmacists to Lead Change at 24th Annual Retail Business Conference 5Cardinal Health Encourages Independent Pharmacists to Lead Change at 24th Annual Retail Business Conference 6Cardica to Announce Fiscal 2014 Fourth Quarter and Full Year Financial Results on Thursday, August 7, 2014 2Dompe announces the Food and Drug Administration (FDA) has granted orphan drug designation to its rhNGF-based treatment for neurotrophic keratitis 2Dompe announces the Food and Drug Administration (FDA) has granted orphan drug designation to its rhNGF-based treatment for neurotrophic keratitis 3Dompe announces the Food and Drug Administration (FDA) has granted orphan drug designation to its rhNGF-based treatment for neurotrophic keratitis 4
... 28, 2011 Streamline Health Solutions, Inc. (Nasdaq: ... workflow solutions for hospitals, announced today that two of ... system in North Carolina, contracted with Streamline Health to ... Resources, which began the beta phase of integration earlier ...
... Inc. (Nasdaq: PCRX ), an emerging specialty pharmaceutical ... quarter ended June 30, 2011 will be released before the ... team will host a conference call to discuss the company,s ... 11, 2011 at 9 a.m. ET. The call can be ...
Cached Medicine Technology:Streamline Health Announces Two Clients Have Contracted for Multiple Integrations to Their Epic Systems 2Streamline Health Announces Two Clients Have Contracted for Multiple Integrations to Their Epic Systems 3Streamline Health Announces Two Clients Have Contracted for Multiple Integrations to Their Epic Systems 4Pacira Pharmaceuticals, Inc. Announces Timing for Second Quarter 2011 Financial Results Webcast and Conference Call 2
... Pump™ is a quiet, compact, efficient vacuum ... The oil-free design and TEFLON®/ETFE coated vapor ... reliability and reduced maintenance. Unique features include ... protection, and a 1-liter post-pump solvent recovery ...
Produces vacuum pressures required for 96 well kits...
... DirectPrep 96 plates and MinElute 96 ... sample handling and accelerated processing; ... plates and MinElute 96 UF PCR ... of internal components by simply separating ...
For vacuum-driven processing of spin columns; Reduced sample handling and accelerated processing; Parallel sample processing using QIAGEN spin columns; Easy cleaning of internal components by simpl...
Medicine Products: