Navigation Links
Differences in generic pill characteristics may lead to interruptions in essential medication use
Date:12/31/2012

Boston, MAGeneric medications currently account for over 70 percent of prescriptions dispensed. However, while generic drugs are clinically bioequivalent to the brand-name version, they often differ in their physical characteristics, such as color and shape. Researchers from Brigham and Women's Hospital (BWH) have found that some patients who receive generic drugs that vary in their color are over 50 percent more likely to stop taking the drug, leading to potentially important and potentially adverse clinical effects.

The study will be published electronically on December 31, 2012 in the Archives of Internal Medicine.

"Pill appearance has long been suspected to be linked to medication adherence, yet this is the first empirical analysis that we know of that directly links pills' physical characteristics to patients' adherence behavior," explained Aaron S. Kesselheim MD, JD, MPH, assistant professor of medicine in the Division of Pharmacoepidemiology and Pharmacoeconomics at BWH, and principal investigator of this study. "We found that changes in pill color significantly increase the odds that patients will stop taking their drugs as prescribed."

The researchers conducted a case-control study of patients taking antiepileptic drugs and compared the odds that patients who did not refill their medication had been given pills that differed in color or shape from the prior prescriptions. Using a large national database of filled prescriptions, when the researchers identified a break in the patient's use of the drug, they looked at the previous two prescription fillings to see if they were the same color and shape. They found that interruptions in the prescription filling occurred significantly more frequently when the pills had different color. Interruptions in antiepileptic drug use for even a few days can raise the risk of seizure and have important medical and social consequences for patients.

These findings offer impo
'/>"/>

Contact: Jessica Maki
jmaki3@partners.org
617-534-1603
Brigham and Women's Hospital
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Study finds significant skull differences between closely linked groups
2. Mayo Clinic study links healthy muscle mass to healthy bones, finds differences by gender
3. Racial differences in diabetes diagnostic thresholds
4. Are there gender differences in anti-HIV drug efficacy?
5. BUSM/VA researchers uncover gender differences in the effects of long-term alcoholism
6. Individual gene differences can be tested in zebrafish
7. Scientists Find Gene Differences in Nonsmokers With Lung Cancer
8. Stanford/Yale study gives insight into subtle genomic differences among our own cells
9. Researchers discover gender-based differences in Alzheimers disease
10. CT depicts racial differences in coronary artery disease
11. U of T Researchers uncover major source of evolutionary differences among species
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... Botanica Day Spa continued ... off September with fall-themed discounts and giveaways. For ... to highlight lumablanc® which contains Pevonia’s exclusive expedited ... the skin. , Lumablanc® was recently released by ... line. The brightening formula, containing a blend of ...
(Date:9/16/2014)... September 16, 2014 A peep-toe shoe ... bootie, or any other dress shoe) in which there ... toes to show. Peep-toe shoes were popular beginning in ... had a brief resurgence in the 1970s/80s, before falling ... have enjoyed some popularity again, with variations such as ...
(Date:9/15/2014)... AZ (PRWEB) September 16, 2014 Hastings ... group in Phoenix Arizona announces one flat attorney fee ... ensuring that clients retain the largest portion possible of ... medical expenses, lost wages and damaged personal property. In ... promise” to clients that simply states that no fees ...
(Date:9/15/2014)... Antonio, TX (PRWEB) September 16, 2014 Crosley ... Crosley and R. Andrew Rodriguez have been named to the ... of excellence in the field of personal injury law. ... make it through a rigorous selection process. First, they must ... firm or have made a noteworthy achievement during the past ...
(Date:9/15/2014)... Ill. Imaging can be a cost-effective way to ... from aggressive intervention, according to a new modeling study ... , The study looked at people with asymptomatic carotid ... supplying blood to the head due to atherosclerosis, or ... of up to 20 percent of ischemic strokes, which ...
Breaking Medicine News(10 mins):Health News:Botanica Day Spa Rolls Out September Specials Highlighting Lumablanc® by Pevonia 2Health News:Botanica Day Spa Rolls Out September Specials Highlighting Lumablanc® by Pevonia 3Health News:Nice Peep Toes Are For Sale At Fecbek.com 2Health News:Hastings And Hastings Announces One Flat Attorney Fee For Personal Injury Cases 2Health News:Hastings And Hastings Announces One Flat Attorney Fee For Personal Injury Cases 3Health News:Thomas A. Crosley and R. Andrew Rodriguez Named 2014 Super Lawyers 2Health News:Imaging identifies asymptomatic people at risk for stroke 2Health News:Imaging identifies asymptomatic people at risk for stroke 3
... of,Public Welfare said today it is working with ... an abandoned child in,Lansdowne, Delaware County., An ... noon today and said, "I left a baby ... without providing any other information. Local law,enforcement was ...
... and large numbers of men, are interested in having cosmetic ... Journal of Plastic and Reconstructive Surgery. , ... in cosmetic surgery, liposuction or both, and another 23 percent ... Among men, 23 percent said they would be interested in ...
... /PRNewswire/ - The IND proposes a randomized Phase,III ... Best Supportive,Care (BSC) versus BSC alone for the ... gastroesophageal junction and stomach who,have failed adjuvant or ... of the IND and will direct the clinical ...
... Oct. 26 In a statewide,effort to help ... violence shelters, the Michigan State Medical Society (MSMS),Foundation ... and,distribute personal care items in conjunction with the ... Day" on,Saturday, October 27., "The women and ...
... WHEATON, Ill., Oct. 26 The following is a,media ... Rehabilitation Hospital is the 2007 recipient of the,James Brady ... or organization,that goes above and beyond to improve lives ... goals of the Brain Injury Association of,Illinois., In ...
... UniCare announced today a policy to,make it easy for ... the prescription drugs they need. A one-time override ... up so,that UniCare policyholders in the affected counties can ... in place for,members living in Los Angeles, Orange, San ...
Cached Medicine News:Health News:Safe Haven Hotline Receives Report of Abandoned Baby in Lansdowne 2Health News:Huge numbers willing to go under knife to alter their appearance, study finds 2Health News:Supratek Pharma Inc. announced today that the U.S. Food and Drug Administration (FDA) has cleared its Investigational New Drug (IND) application for SP1049C for the treatment of metastatic adenocarcinoma of the upper gastrointestinal tract 2Health News:Michigan State Medical Society Foundation 'Makes A Difference' by Assisting Those in Crisis Shelters 2Health News:Marianjoy Rehabilitation Hospital to Receive James Brady Award From Brain Injury Association of Illinois 2Health News:UniCare Announces Temporary Pharmacy Guidelines for Customers Affected by the California Wildfires 2
(Date:9/15/2014)... 2014 /PRNewswire-iReach/ -- On September 8, 2014, Dr. ... submitted a Citizen Petition to Dr. Margaret ... add another Black Box Warning to Levaquin, Cipro, ... for a Black Box Warning for the following ... thoughts or acts, loss of consciousness, delirium, depressed ...
(Date:9/15/2014)... BRUSSELS , Sept. 15, 2014 ... Brussels:UCB) today announced results from several exploratory analyses of ... with low bone mineral density (BMD). Romosozumab is an ... inhibiting the protein sclerostin, thereby increasing bone formation and ... American Society for Bone and Mineral Research (ASBMR) 2014 ...
(Date:9/15/2014)... DALLAS , Sept. 15, 2014 /PRNewswire-iReach/ -- MedicOne ... ambulance transport services, has been selected by Inc. ... companies in America. Photo - ... Inc. 500|5000 list identifies successful, privately-held companies with ... MedicOne Medical Response, one of only two ambulance ...
Breaking Medicine Technology:Quinolone Vigilance Foundation Supports Citizen Petition Requesting Another Black Box Warning for Levaquin, Cipro, Avelox 2Quinolone Vigilance Foundation Supports Citizen Petition Requesting Another Black Box Warning for Levaquin, Cipro, Avelox 3New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 2New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 3New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 4New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 5New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 6New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 7New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 8New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 9New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 10New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 11New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 12New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 13New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 14New Analyses Of Phase 2 Study Presented At ASBMR Show Romosozumab Treatment Resulted In Continued Increases In Bone Mineral Density 15MedicOne Medical Response Named to 2014 Inc. 5000 Fastest Growing Companies List 2MedicOne Medical Response Named to 2014 Inc. 5000 Fastest Growing Companies List 3
... experts have launched a statewide immunization campaign entitled, "Immunize ... parents who are vaccinating their children that they are ... effective in preventing serious childhood illness. Initiated ... by the Colorado Department of Public Health and Environment,s ...
... (Pink Sheets: SNDY ) is pleased to announce ... new product development, new product sales and the completion of ... initiative, which is a major step in obtaining the CE ... European Union. Early in 2010, Solos retained Expert ...
Cached Medicine Technology:State Launches 'Immunize for Good' Marketing Campaign to Remind Parents Immunizations are Safe and the Best Way to Prevent Childhood Illness 2Solos Endoscopy, Inc. Trends toward Strong Continued Growth in 2011 2
... Carl Zeiss has successfully advanced into the ... success of this instrument is by no ... and stylish design. Maximum ergonomic convenience is ... be used with a surgical microscope, allowing ...
... superior tissue excision with precision-matched, diamond-honed tips. ... pattern to capture loose bodies drawn into ... pin buffering system to minimize tip breakage ... pin buffering system applies increasing tension to ...
Leg holder for arthroscopy....
Osteoprep instruments provide an array of bone shaping devices especially suited for notchplasties....
Medicine Products: