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Diets High in Fructose May Harm Liver in Some, Scientists Warn
Date:9/17/2012

revealed that participants with high dietary fructose consumption had lower liver ATP levels when the study began and a more significant change in ATP after the fructose test. The researchers also noted that those with high uric acid levels had lower ATP stores following high fructose intake.

Based on their findings, the researchers suggested uric acid, which is produced by the breakdown of natural food substances known as purines, may serve as a marker for increased fructose consumption and low levels of liver ATP.

"High fructose consumption and elevated levels of uric acid are associated with more severe depletion of liver ATP," Abdelmalek said in the news release. "Our findings suggest that increased dietary fructose intake may impair liver 'energy balance.' Further research to define the clinical implications of these findings on metabolism and NAFLD is necessary."

Although the study found an association between a diet high in fructose and liver risks in certain people, it did not prove a cause-and-effect relationship.

More information

The American Heart Association has more about sugars and high-fructose corn syrup.

-- Mary Elizabeth Dallas

SOURCE: Hepatology, news release, Sept. 13, 2012


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