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Dieter Luetticken Award 2008 Recognizes Development of New Vaccine Quality Control Assay
Date:4/7/2009

BOXMEER, Netherlands, April 7 /PRNewswire-FirstCall/ -- Intervet/Schering-Plough Animal Health today announces that the Dieter Luetticken Award 2008 for alternatives in animal testing goes to Dr. Ivo Claassen for a project that he has managed at the Central Veterinary Institute (CVI), Lelystad (the Netherlands). The announcement was made by Prof. Coenraad Hendriksen, chairperson of an independent expert jury panel and Professor of Alternatives to Animal Testing at Utrecht University (the Netherlands).

Dr. Claassen had a leading role in an interdisciplinary team with Dr. Riks Maas and Dr. Hok Oei from the CVI in close collaboration with Dr. Jean Marc Spieser and Dr. Catherine Milne of the European Directorate on Quality of Medicines (EDQM), Strasbourg (France). The team developed an in vitro potency test for the routine quality control of inactivated Newcastle Disease Virus (NDV) vaccines. Previously, quality control of NDV vaccines included an in vivo potency assay in chickens. The new method allows avoiding the use of chickens and has now been included in the respective European Pharmacopoeia monograph as an additional potency assay to release NDV vaccines. The research project was largely funded by the Department of Agriculture, Nature and Food Quality in the Netherlands.

"The new in vitro potency test is an attractive alternative for the existing in vivo potency tests especially with regard to the objective of the European regulatory authorities to replace, reduce and refine (3R) the use of laboratory animals for production and quality control of immuno-biologicals," said jury chair Prof. Hendriksen.

Intervet/Schering-Plough Animal Health, a leading global animal health company, sponsors the international Dieter Luetticken Award for alternatives in animal testing to support individual scientists and life science research institutions that make significant contributions to the 3R
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SOURCE Schering-Plough
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