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Dietary medium chain triglycerides prevent nonalcoholic fatty liver disease
Date:4/24/2013

ials may be initiated in patients with metabolic syndrome." Dr. Ronis states that "the technology to produce synthetic cooking oils incorporating MCT is already with us. The Japanese are currently testing an oil containing monounsaturated 18:1 fatty acids and MCT for beneficial health effects. There is no reason why similar synthetic products incorporating saturated fatty acids such as 16:0 or 18:0 and MCT cannot be developed for the US market".

Dr. Steven R. Goodman, Editor-in-Chief of Experimental Biology and Medicine, said "with obesity and type II diabetes on the rise development of nonalcoholic fatty liver disease (NAFLD) that can lead to hepatitis, fibrosis and liver cancer is an increasing problem. Dr. Martin Ronis and colleagues using an animal model of NAFLD have shown that substitution of saturated fat in the form of medium chain triglycerides (MCT) for polyunsaturated fats can prevent the progression of NAFLD-associated liver injury. As pointed out by Ronis and colleagues this provides a potential future therapy for NAFLD where we simply alter our cooking oils to contain therapeutic levels of MCTs."


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Contact: Martin J. Ronis
ronismartinj@uams.edu
Society for Experimental Biology and Medicine
Source:Eurekalert

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