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Diet, Exercise May Modify Breast Cancer Risks
Date:11/18/2008

n fat metabolism, than those mice only put on an exercise program or those allowed to eat at will with no forced exercise. The calorie-restricted mice also had increased levels of adiponectin, a hormone produced in fat tissue that regulates some metabolic processes, the researchers said.

Some of the cell signaling pathways these hormones manage converge at mTOR, and the researchers found that the key proteins found downstream of mTOR were less active in both the calorie-restricted and exercised mice compared to the controls.

"These data suggest that although exercise can act on similar pathways as caloric restriction, caloric restriction possesses a more global effect on cell signaling and, therefore, may produce a more potent anti-cancer effect," Nogueira said.

More information

The American Cancer Society has more about breast cancer.



-- Kevin McKeever



SOURCE: American Association for Cancer Research, news release, Nov. 18, 2008


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