Navigation Links
Diesel exhaust associated with lethargy in offspring

Breathing diesel exhaust during pregnancy is associated with sluggishness in offspring. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology studied the effects of pollution exposure in mice, finding that the offspring of mothers who breathed diesel fumes while pregnant were less likely to show spontaneous movement.

Ken Takeda, from Tokyo University of Science, Japan, worked with a team of researchers to carry out the study in pregnant mice, randomly assigned to be exposed to diesel exhaust or filtered air. He said, "We then took ten random male pups from each group and monitored their movement at 10 minute intervals for 3 days. We found that the mice whose mothers had breathed the fumes showed significantly less spontaneous motor activity and that this inactivity was associated with alterations in brain metabolism of neurotransmitters".

Spontaneous movement rates are a validated model for measuring the effect of brain activity or neural transmission to peripheral muscles. For instance tranquilizers are known to diminish brain activity and this leads to a decrease in movement. The researchers speculate that certain components, such as ultrafine particles, in the diesel exhaust may be translocated into the offspring of mice, disturbing the normal timetable of development in offspring and leading to the behavioral and physiological abnormalities seen in this study. Alternatively, or additionally, diesel exhaust exposure may affect the mother's behavior toward the pups after birth, which could also cause lethargy and altered brain chemistry.

Takeda concludes, "Further investigations are needed to clarify the critical factors or components responsible for the effects on offspring. Since the concentration of diesel exhaust we used was close to the environmental quality standard of air in Japan, these findings warrant a revisiting of present pollution standards in each country of the world".


Contact: Graeme Baldwin
BioMed Central

Related medicine news :

1. Study evaluates costs and benefits associated with new colon cancer therapies
2. New Study Finds Cholesterol-Related Gene Associated with Mild Cognitive Impairment, a Precursor of Alzheimer's Disease
3. High weight associated with risk of colorectal tumors without microsatellite instability
4. Coffee Drinking and Caffeine Associated With Reduced Risk of Hospitalization for Heart Rhythm Disturbances
5. Common osteoporosis drugs are associated with a decrease in risk of breast cancer
6. Hormone thought to slow aging associated with increased risk of cancer death
7. MedQuist Launches EHR Integration for Dictations Associated with Template-based Clinical Documentation
8. New developments in nanotechnology tackle the 2 biggest problems associated with chemotherapy
9. Pretreatment SUV associated with head and neck cancer treatment outcomes, may help decide treatment plans
10. Increased HAART coverage associated with 50 percent drop
11. New research shows emotional impact of low sexual desire and associated distress
Post Your Comments:
(Date:11/25/2015)... ... 2015 , ... Brillianteen, McGaw YMCA’s student-produced musical show, will ... Anniversary Brillianteen Revue, scheduled for March 4-6, 2016. Auditions for this final production ... been a treasured tradition for numerous families in the Evanston community. Over the ...
(Date:11/25/2015)... , ... November 25, 2015 , ... “While riding the ... inventor, from Bronx, N.Y. “I thought there had to be a convenient and comfortable ... PROTECTOR. , The PROTECTOR enables disabled individuals to safely travel during cold or inclement ...
(Date:11/25/2015)... , ... November 25, 2015 , ... ... provide scholarships for people struggling with eating disorders as a result of the ... second annual event, held at Fox Run Golf Club in Eureka, will help ...
(Date:11/25/2015)... ... 25, 2015 , ... "When I underwent breast reconstruction following ... uncomfortable," said an inventor from Bronx, N.Y. "In order to meet my own ... BRA for added comfort and support. The bra is easier to put on ...
(Date:11/25/2015)... ... ... An unlikely combination of recycled plastic shopping bags in ... to have a more dignified and comfortable night’s sleep. , Residents of Friendship ... bags into sleeping mats for the homeless. The project, according to Jeannette ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 ... "2016 Future Horizons and Growth Strategies ... Market: Supplier Shares, Country Segment Forecasts, Competitive ... offering. --> ) has ... Future Horizons and Growth Strategies in the ...
(Date:11/26/2015)... 2015 ... the  "2016 Future Horizons and Growth ... Monitoring (TDM) Market: Supplier Shares, Country ...  report to their offering.  --> ... addition of the  "2016 Future Horizons ...
(Date:11/26/2015)... DUBLIN , Nov. 26, 2015 ... the addition of the "2016 Future Horizons ... Monitoring (TDM) Market: Supplier Shares, Country Segment Forecasts, ... offering. --> ... comprehensive analysis of the Italian therapeutic drug monitoring ...
Breaking Medicine Technology: