Navigation Links
Diesel exhaust associated with lethargy in offspring

Breathing diesel exhaust during pregnancy is associated with sluggishness in offspring. Researchers writing in BioMed Central's open access journal Particle and Fibre Toxicology studied the effects of pollution exposure in mice, finding that the offspring of mothers who breathed diesel fumes while pregnant were less likely to show spontaneous movement.

Ken Takeda, from Tokyo University of Science, Japan, worked with a team of researchers to carry out the study in pregnant mice, randomly assigned to be exposed to diesel exhaust or filtered air. He said, "We then took ten random male pups from each group and monitored their movement at 10 minute intervals for 3 days. We found that the mice whose mothers had breathed the fumes showed significantly less spontaneous motor activity and that this inactivity was associated with alterations in brain metabolism of neurotransmitters".

Spontaneous movement rates are a validated model for measuring the effect of brain activity or neural transmission to peripheral muscles. For instance tranquilizers are known to diminish brain activity and this leads to a decrease in movement. The researchers speculate that certain components, such as ultrafine particles, in the diesel exhaust may be translocated into the offspring of mice, disturbing the normal timetable of development in offspring and leading to the behavioral and physiological abnormalities seen in this study. Alternatively, or additionally, diesel exhaust exposure may affect the mother's behavior toward the pups after birth, which could also cause lethargy and altered brain chemistry.

Takeda concludes, "Further investigations are needed to clarify the critical factors or components responsible for the effects on offspring. Since the concentration of diesel exhaust we used was close to the environmental quality standard of air in Japan, these findings warrant a revisiting of present pollution standards in each country of the world".


Contact: Graeme Baldwin
BioMed Central

Related medicine news :

1. Study evaluates costs and benefits associated with new colon cancer therapies
2. New Study Finds Cholesterol-Related Gene Associated with Mild Cognitive Impairment, a Precursor of Alzheimer's Disease
3. High weight associated with risk of colorectal tumors without microsatellite instability
4. Coffee Drinking and Caffeine Associated With Reduced Risk of Hospitalization for Heart Rhythm Disturbances
5. Common osteoporosis drugs are associated with a decrease in risk of breast cancer
6. Hormone thought to slow aging associated with increased risk of cancer death
7. MedQuist Launches EHR Integration for Dictations Associated with Template-based Clinical Documentation
8. New developments in nanotechnology tackle the 2 biggest problems associated with chemotherapy
9. Pretreatment SUV associated with head and neck cancer treatment outcomes, may help decide treatment plans
10. Increased HAART coverage associated with 50 percent drop
11. New research shows emotional impact of low sexual desire and associated distress
Post Your Comments:
(Date:11/25/2015)... ... November 25, 2015 , ... Since its ... comprehensive solutions involving adult stem cell therapies to patients with chronic degenerative medical ... name as a Registered Trademark (RTM). , Organizations are required to hold a ...
(Date:11/24/2015)... ... November 24, 2015 , ... Dr. Todd S. Afferica, a noted ... to many of his patients. Dr. Afferica now uses the BIOLASE WaterLase iPlus 2.0™ ... of time the doctor uses other traditional cutting tools, such as the scalpel and ...
(Date:11/24/2015)... ... , ... In an article published November 12th by Obesity News ... or are not eligible for bariatric surgery. The article explains that candidates for weight ... 100 pounds overweight, or have a BMI of 35 and over with at least ...
(Date:11/24/2015)... Salt Lake City, UT (PRWEB) , ... November 24, 2015 , ... ... according to Forbes Magazine. For a business, it is critical that the first impression ... of a business, they are not likely to buy anything or want to return. ...
(Date:11/24/2015)... ... 2015 , ... Cancer patients, survivors, caregivers, family members and ... taping of the next CURE Connections® video series on Saturday, Dec. ... at Georgetown University Hotel & Conference Center in Washington, D.C. , CURE Connections, ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... , November 24, 2015 ... --> adds Latest Guidebook for ... of 217 pages published in November 2015 to ... online business intelligence library at . ... of the fastest growing global economies with a ...
(Date:11/24/2015)... LONDON , November 24, 2015 ... platform for scientists - since it was launched just six ... collaboration, reference management and authoring platform for scientists - since ... One million references have been loaded on to F1000Workspace ... for scientists - since it was launched just six months ...
(Date:11/24/2015)... , November 24, 2015 st  Scientific ... North America (RSNA) taking place in Chicago ... Booth 1122, Hall A. --> st  Scientific Assembly and ... (RSNA) taking place in Chicago ... Hall A. --> Molecular Dynamics will present its revolutionary ...
Breaking Medicine Technology: