Navigation Links
Diagnostic Mammogram Readings Vary by Radiologist

Radiologists' experience and affiliation often influenced results, study found

TUESDAY, Dec. 11 (HealthDay News) -- Radiologists are human, too, and vary widely in their interpretations of diagnostic mammograms, a new study found.

The differences weren't due to differences in patients so much as they were due to differences in the radiologists' experience and affiliation.

The authors of the study, published in the Dec. 11 issue of the Journal of the National Cancer Institute, did find certain factors that predicted more accurate mammography readings.

"This is a little bit of a warning that there is a wide variation," said Diana Miglioretti, study lead author and an associate investigator at Group Health Center for Health Studies in Seattle. "If possible, go to a facility with a breast-imaging specialist, someone who also does biopsies and ultrasounds."

"You definitely want to have radiologists interpreting mammograms who do a substantial number of mammograms in a year -- that's number one," added Dr. Jay Brooks, chairman of hematology/oncology at Ochsner Health System in Baton Rouge, La. "Number two, you want to make sure that they read mammograms in a continuum so that they have previous mammograms to read it against. That's why I encourage patients to stay in one system where X-rays are looked at longitudinally. The third thing is that the radiologist is not reading this by him or herself, that there are other radiologists that can come into the room and look at the films."

Previous studies have also shown variability in how radiologists interpret mammograms, but those studies primarily involved screening mammograms. Diagnostic mammograms are performed after an abnormality of some kind has already been detected either from a screening mammogram or a physical exam.

The accuracy of diagnostic mammograms is extremely important, given that the rate of breast cancer is 10 times higher with those images than in screening mammograms, the study authors said.

For the study, the researchers looked at the records of 123 radiologists who had collectively interpreted 35,895 diagnostic mammograms at 72 U.S. facilities.

Close to 80 percent of breast cancers were diagnosed correctly. But sensitivity -- or the ability to accurately detect cancer -- ranged from 27 percent to 100 percent for different radiologists. False-positives (biopsies performed when there was no cancer) ranged from zero to 16 percent.

But 4.3 percent of women who had no cancer were tentatively told they had the disease, based on the mammogram (i.e. they received a false-positive reading).

The strongest factor linked to better accuracy was if the radiologist was affiliated with an academic medical center. Such radiologists were correct 88 percent of the time, compared to 76 percent for other radiologists. Radiologists at academic institutions were also less likely to report false-positive findings.

But the study results have to be taken with a grain of salt, the authors said, because only seven radiologists affiliated with academic institutions were represented in the study. This is more or less in keeping with the "real world," where academic radiologists interpret only 6.5 percent of mammograms across the nation, the authors said.

Radiologists who spent 20 percent or more of their time on breast imaging were more accurate than those who spent less time on breast imaging -- 80 percent versus 70 percent.

Interestingly, more experienced radiologists were less likely to recommend biopsies, but they missed more cancers than those with less experience, the study authors said.

"Radiologists who had been in practice longer had a lower threshold for recalling women for biopsies," Migliorettii said. "They had fewer false-positives but lower sensitivity, meaning they missed more cancers."

More information

The Radiological Society of North America has more on diagnostic mammography.

SOURCES: Diana Miglioretti, Ph.D., associate investigator, Group Health Center for Health Studies, Seattle; Jay Brooks, M.D., chairman of hematology/oncology, Ochsner Health System, Baton Rouge, La.; Dec. 11, 2007, Journal of the National Cancer Institute

Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Mayo Clinic researchers discover new diagnostic test for detecting infection in prosthetic joints
2. The ScottCare Corporation Completes Acquisition of Rozinn Electronics, a Leading Manufacturer of Cardiac Diagnostic Products
3. Quest Diagnostics to Speak at the Bear Stearns Healthcare Conference
4. Pathway Diagnostics Announces Commercial Availability of SensiTrop(TM) HIV Co-receptor Tropism Assay
5. Hypertension Diagnostics Announces Fiscal Year 2007 Results
6. Foundation Venture Capital Group, LLC Invests in Start Up Committed to Breast Cancer Diagnostics
7. Meretek Diagnostics and Otsuka America Pharmaceutical, Inc. Announce Completion of Merger
8. Siemens Medical Solutions Diagnostics Announces the Release of the Rapidlab 1200 Series Version 2.0 Software
9. Aloka to Unveil New ProSound Diagnostic Ultrasound System at the 17th World Congress on Ultrasound in Obstetrics and Gynecology, 7th to 11th of October 2007 in Florence, Italy
10. New peritoneal dialysis diagnostic discovered
11. Virginia G. Piper Charitable Trust and Flinn Foundation launch molecular diagnostics initiative
Post Your Comments:
(Date:12/1/2015)... CHICAGO (PRWEB) , ... December 01, 2015 , ... ... risk quantification and optimization of adjunctive imaging is the focus of numerous abstracts ... (RSNA) meeting, November 29-December 4, 2015. Nine abstracts highlight the use of ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... everything. That is why Hollister Incorporated has launched the VaPro Plus Pocket™ touch ... product in the VaPro touch free catheter portfolio,” said Michael Gresavage, Vice President ...
(Date:12/1/2015)... ... December 01, 2015 , ... SAN FRANCISCO, Calif. (December ... the organization has awarded Education and Developmental Therapies (EDT), an Applied Behavior Analysis ... celebrates exceptional special needs providers that excel in synthesizing the areas of clinical ...
(Date:12/1/2015)... ... December 01, 2015 , ... ... it has been awarded a fixed price per sprint agile development contract to ... at $34 million over five years, provides software engineering, infrastructure, as well as ...
(Date:12/1/2015)... (PRWEB) , ... December 01, 2015 , ... ... clinical solutions for the care management and population health arenas, is pleased to ... clinical and cost containment services, has successfully implemented the ACUITY Complete Care™ Management ...
Breaking Medicine News(10 mins):
(Date:12/1/2015)... VIEJO, Calif. , Dec. 1, 2015 /PRNewswire/ ... the prevalence of symptoms for pseudobulbar affect (PBA), ... outbursts of laughing and/or crying resulting from certain ... use of antipsychotic medications in nursing home residents, ... Geriatric Psychiatry. The study showed that almost one ...
(Date:12/1/2015)... , Dec. 1, 2015 Research and ... of the "2016 Global Enteric Disease Testing ... Salmonella, Shigella, Vibrio, Yersinia--France, Germany, Italy, Japan, Spain, ... Japan . --> ... The report is based on a combination ...
(Date:12/1/2015)... UPPSALA, Sverige, December 1, 2015 ... Breast Cancer Study Group (IBCSG, Bern ... att ingå i en klinisk studie av palbociclib, ... --> Studien, med namn PYTHIA, ... med anti-hormonella läkemedel i kombination med palbociclib, som ...
Breaking Medicine Technology: