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Diagnosis of arthritis 5 years earlier in childless women compared to those with children
Date:6/11/2009

des before the age of 45 years. Information about parous status was confirmed through linking the NOR-DMARD patient cohort with the Medical Birth Registry of Norway (MBRN).

The time of diagnosis was recorded at the time of enrollment into the study and group comparisons were performed with Mann-Whitney U test for continuous variables and chi-square tests for categorical variables. Cox multiple regression analyses were used to compare the age at diagnosis for nulliparous and parous women. The analyses were adjusted for smoking, length of education and age at the time of the current analyses.

Of the 557 women identified, 163 were nulliparous and 394 were parous (with a minimum of one delivery). The mean age at the time of the current analyses was 36.2 years for the nulliparious women, and 41.1 years for the parous women (p< 0.001).

Nulliparous women were found to have a significantly higher educational level than parous women (p=0.02), although smoking habits were not found to be significantly different between the groups (p=0.11). Unadjusted in the Cox multiple regression analyses, the nulliparous women were diagnosed at a significantly earlier age than the parous women: RR (95% CI) 1.83 (p< 0.001). However, when adjusted for educational level, smoking and age at the current analyses, a significant difference was still observed: RR (95% CI) 1.23 (p=0.04).


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Contact: Rory Berrie
eularpressoffice@uk.cohnwolfe.com
44-078-943-86425
European League Against Rheumatism
Source:Eurekalert

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