Navigation Links
'Diabulimia' Triples Risk of Death Among Women With Diabetes
Date:2/27/2008

Restricting insulin doses to lose weight increases chances of complications, study finds

WEDNESDAY, Feb. 27 (HealthDay News) -- Women with type 1 diabetes who take less insulin than they should to try to lose weight triple their risk of dying compared to women who do not skip insulin doses, a new study finds.

"This is a very important women's health issue in diabetes," said Ann E. Goebel-Fabbri, lead author of a study in the March issue of Diabetes Care. "It happens at shockingly high rates, and, if we can detect this problem sooner and earlier, one would hope that we could direct patients to effective treatment."

Insulin treatment has been linked to weight gain; this practice of restricting insulin is referred to as "diabulimia," and is a dangerous way to shed pounds quickly. Previous studies have shown that women with diabetes are almost 2.5 times more likely to develop an eating disorder than women without diabetes. Research also suggests that diabulimia can increase the risk of complications such as foot and vision problems, along with kidney damage, but there has been little research on mortality.

People with type 1 diabetes have completely lost the ability to produce their own insulin, the hormone necessary to usher glucose into cells, where it is stored for energy. Regular injections of insulin essentially replace what the body used to produce naturally.

But shortchanging insulin doses means glucose levels are not controlled and, as the landmark Diabetes Control and Complications Trial established, persistently high blood glucose levels lead to serious complications, including eye and kidney trouble, and even death.

"Insulin is the hormone that allows the transport of glucose from the bloodstream into cells for use, so either the sugar gets used then and there for energy or it gets stored for later use," explained Goebel-Fabbri, a psychologist and investigator in the Section on Behavioral and Mental Health at Joslin Diabetes Center and an instructor at Harvard Medical School. "So, if you're not taking enough insulin, sugar increases in concentration in the blood, the body needs to find a way of excreting it, and the calories from that sugar get excreted in the urine."

Unfortunately, half of adult diabetics do not maintain recommended glycemic levels.

This study included a total of 234 women, mean age 45, who were followed for 11 years. Participants had had diabetes for a mean of 28 years by the end of the follow-up.

Almost one-third of women reported taking less insulin than they should.

These women tripled their risk of dying compared with women who did not restrict their insulin. They also died younger (45 versus 58) and had higher rates of kidney and foot problems.

Women in the two groups did not differ when it came to depression, anxiety, fear of hypoglycemia (low blood sugar), or general psychiatric symptoms. This left an eating disorder, rather than general psychological issues, as the likely culprit.

"We need to start including this kind of screening for diabetes practice," Goebel-Fabbri said.

More information

Visit the American Diabetes Association for more on type 1 diabetes.



SOURCES: Ann E. Goebel-Fabbri, Ph.D., psychologist and investigator, Section on Behavioral and Mental Health, Joslin Diabetes Center, and instructor, Harvard Medical School, Boston; March 2008, Diabetes Care


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Hypertension Triples Womens Diabetes Risk
2. Drugs used for cancer-associated anemia linked with increased risk of blood clots, death
3. Drug for anemic cancer patients raises risk of death
4. Anemia Drugs for Cancer Patients Increase Death Risk
5. Drugs, Doctors and Death: Heath Ledger Becomes Another Victim
6. Heart Disease Deaths Over-Reported in New York City
7. Clarity for Consumers on Botox Complication and Death Reports
8. In-Hospital Stroke Deaths Rise on Nights, Weekends
9. Cancer Death Rates Still Declining
10. Report says half a million cancer deaths have been averted since death rate drop
11. US cancer deaths down but far too few Americans screened for colon cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
'Diabulimia' Triples Risk of Death Among Women With Diabetes
(Date:6/26/2016)... ... 2016 , ... PawPaws brand pet supplements owned by Whole Health ... the health of felines. The formula is all-natural and is made from Chinese herbs ... Cat Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia ...
(Date:6/25/2016)... ... ... The temporary closing of Bruton Memorial Library on June 21 due to a possible lice ... overlooked aspect of head lice: the parasite’s ability to live away from a human host, ... a necessary one in the event that lice have simply gotten out of control. , ...
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary of ... award to iHire in recognition of their exemplary accomplishments in worksite health promotion. , ... Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire was ...
(Date:6/24/2016)... PASADENA, CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. ... he would lash out at his family verbally and physically. , “When something upset him, ... table, he would use it. He would throw rocks at my other children and say ...
(Date:6/24/2016)... ... ... of Topricin and MyPainAway Pain Relief Products, join The ‘Business for a Fair Minimum Wage’ ... 2020 and then adjusting it yearly to increase at the same rate as the median ... floor does not erode again, and make future increases more predictable. , The company is ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)...  In a startling report released today, National Safety Council ... a comprehensive, proven plan to eliminate prescription opioid overdoses. ... states are tackling the worst drug crisis in recorded U.S. history, ... Kentucky , New Mexico , ... the 28 failing states, three – Michigan , ...
(Date:6/23/2016)... , June 23, 2016 Research and ... News Issue 52" report to their offering. ... influenza treatment creates a favourable commercial environment for MedImmune to ... patient base that will serve to drive considerable growth for ... would serve to cap sales considerably, but development is still ...
(Date:6/23/2016)... and BOGOTA, Colombia , June 23, 2016  Astellas today announced the establishment of ... Farma Brasil as the company,s second affiliate in Latin America . ... ... Manager of Astellas Farma Colombia ... ...
Breaking Medicine Technology: