Navigation Links
Diabetic potential to create own insulin
Date:6/14/2010

Researchers from the Peninsula Medical School, working in collaboration with colleagues from Glasgow Royal Infirmary and the University of Brighton, have used a unique collection of pancreas specimens taken from patients who died soon after diagnosis of type 1 diabetes to show that they respond to the ongoing process of destruction by inducing their islet cells to proliferate.

The research is published on-line at Diabetologia and is funded by Juvenile Diabetes Research Foundation.

The findings are important because, until now, it has been generally believed that, in humans, beta cells divide only very infrequently after the first year or so of life and that they do not readily proliferate once type 1 diabetes is diagnosed. By studying the same unique collection of pancreas specimens that last year led the research team to conclude that some cases of type 1 diabetes may have a viral cause, this current study presents evidence that there is a 10-fold increase in islet cell replication in patients recently diagnosed with type 1 diabetes. A similar response had been seen previously in an animal model of type 1 diabetes by a member of the team, Professor Adrian Bone (University of Brighton) but it was not known if accelerated β-cell replication also occurs in human patients.

The factors that trigger the replication process in patients with type 1 diabetes are still unclear, although the study shows a correlation with the infiltration of immune cells (which suggests that an immune mediator is likely to be involved).

The results of the research offer the hope that, in future, it might be possible to encourage a newly diagnosed type 1 diabetes patient's own beta cells to reproduce as a means of replacing those being destroyed by the disease. The development of such a therapy could mean that some patients with type 1 diabetes would be able to produce their own insulin for a longer period, thereby reducing the need for pha
'/>"/>

Contact: Andrew Gould
andrew.gould@pms.ac.uk
44-139-268-6107
The Peninsula College of Medicine and Dentistry
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Glucose Tattoo Could Track Blood Sugar Levels for Diabetics
2. Aspirin recommendations changed for many younger diabetic patients
3. Caring for Diabetic Pets Helps Humans Get Healthier
4. Experts Advise At-Risk Diabetics to Begin Daily Aspirin Later
5. Frequent Doctor Visits Help Diabetics Control Blood Pressure
6. Pig Pancreas Cells Help Type 1 Diabetics
7. Healthy Pre-Diabetics Still Face Heart Disease Threat
8. Drug a New Treatment Option for Diabetic Eye Disease
9. Tight Blood Sugar Control May Not Harm Diabetics
10. High-Dose Vitamin B Risky for Diabetics With Kidney Disease
11. Comparative-effectiveness study confirms new treatment for diabetic macular edema
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... -- Expectant parents should leave prenatal picture-taking to medical ... Use of ultrasound imaging and heartbeat monitors to get ... agency warns. "Although there is a lack ... and heartbeat monitors, prudent use of these devices by ... FDA biomedical engineer, said in an agency news release. ...
(Date:12/17/2014)... HealthDay Reporter , TUESDAY, Dec. 16, ... America, and work commitment is a big reason why, new ... said Dr. Mathias Basner, an assistant professor of sleep and ... of Medicine. A time-use survey of nearly 125,000 Americans, ... main activity exchanged for sleep. Short sleepers -- those who ...
(Date:12/15/2014)... 15, 2014 South Florida’s leading urgent care ... can be a daze of hassle, hustle, and bustle that ... decking halls, to burns when making special meals and heartburn ... can happen at any time. To prevent this season of ... made a list of helpful and healthful holiday tips to ...
(Date:12/15/2014)... News) -- Expert pilots process visual information more efficiently ... better decisions during landings, a new study shows. ... pilots to master, and 36 percent of all airplane ... final approach and landing. Researchers monitored the brain ... pilots while they were at the controls of a ...
(Date:12/15/2014)... 15, 2014 At the leading, long-established ... AutismOne and Focus Autism will welcome ... research on the effects of toxins to children’s health, ... information. , Luminaries such as Dr. Lucija Tomljenovic ... with esteemed, credentialed colleagues of the United States to ...
Breaking Medicine News(10 mins):Health News:FDA Warns Against Fetal 'Keepsake' Videos 2Health News:Work Steals Valuable Sleep Time, Study Finds 2Health News:Work Steals Valuable Sleep Time, Study Finds 3Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Study Shows Why Expert Pilots Are Experts 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 2Health News:AutismOne and Focus Autism Collaborate on Scientific Conference; International Group of Researchers to Present in Chicago, May 2015 3
... A $1.3 million grant to Indiana University from the ... the East African Center of Excellence in Health Informatics. ... of one of the world,s foremost informatics programs at ... leading academic medical centers in East Africa at Moi ...
... ... sheds light on social media behaviors among large and small animal veterinarians, including Internet ... dog owners and cat owners. , ... (PRWEB) November 16, 2009 -- More than half of small animal ...
... , Accepts Report of Blue Ribbon Advisory Panel ... century care, Secretary of Veterans Affairs Eric K. Shinseki has ... Affairs (VA) and the schools that train the nation,s health ... higher education for health care professionals have been essential partners ...
... , Transforming school food high priority ... Foundation announced today it will invest $32,450,000 over the span ... are working to increase access to healthy food and physical ... This investment -- called Food & Community -- brings the ...
... , , MILWAUKEE and MENASHA, Wis., ... and Affinity Health System (Affinity) announced today a new agreement ... from the award-winning health system at in-network rates and benefit ... of the broadest networks of doctors, hospitals and specialists in ...
... for patients 80 and older, study finds , MONDAY, ... heart attack patients in the United States is good, ... older, a new study suggests. , Researchers analyzed 2000-2009 ... centers enrolled in the American Heart Association,s "Get With ...
Cached Medicine News:Health News:Indiana University receives NIH grant to improve health care in East Africa 2Health News:Indiana University receives NIH grant to improve health care in East Africa 3Health News:Small and Large Animal Veterinarians Actively Texting, E-mailing for Business and Personal Reasons 2Health News:Small and Large Animal Veterinarians Actively Texting, E-mailing for Business and Personal Reasons 3Health News:Secretary Enhancing Partnerships with Medical Schools 2Health News:W.K. Kellogg Foundation Grants $32.5 Million to Improve Access to Fresh Food and Physical Activity for Children 2Health News:Anthem Blue Cross and Blue Shield Adds Affinity Health System to Provider Network 2Health News:Anthem Blue Cross and Blue Shield Adds Affinity Health System to Provider Network 3
(Date:12/17/2014)... and RALEIGH, N.C. ... Marketing Communications, LLC (CTMC), and Integrated Clinical Trial ... recruitment and retention for clinical trials announce that ... Clinical Trial Marketing Services (i-CTMS). i-CTMS will provide ... services to pharmaceutical, biotechnology and medical device companies. ...
(Date:12/15/2014)... , December 15, 2014 ... Am 19. und 20. Februar sind alle ... SAFE MEDICINE ECOSYSTEM PARTNER PROGRAMM ™ 2015 ... besuchen. Diese Tagung soll dazu ... Möglichkeit geben, die neue profitablen Unternehmensdienstleistungen, die ...
(Date:12/15/2014)... Dec. 12, 2014 Research and Markets ... "Electrocardiogram (ECG) Devices - Global Trends, Estimates and ... http://photos.prnewswire.com/prnh/20130307/600769 Global Electrocardiogram ... by 2016. The North America ... share while Europe claims approximately ...
Breaking Medicine Technology:Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 2Integrated Clinical Trial Services and Clinical Trial Marketing Communications Form Joint Venture 3Symposium über Aegates Ecosystem-Partner-Programm für sichere Medikamente vom 19. - 20. Februar 2015 in Amsterdam 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 2Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 3Electrocardiogram (ECG) Devices - Global Trends, Estimates and Forecasts, 2012-2018 4
... LOS ANGELES, December 2, 2011  WestPark Capital, Inc. announced ... (NYSE Amex: ISR). A total of 2,817,988 shares of common ... of common stock were sold, generating gross proceeds of ... used to fund new applications for IsoRay,s Cesium-131 technology ...
... SPRINGFIELD, Ill., Dec. 2, 2011  H. D. Smith and Adventist ...  announce a five-year agreement in which H. D. Smith will ... health system,s hospitals, home healthcare and long term care facilities. ... D. Smith will provide medical product supply chain services and ...
Cached Medicine Technology:WestPark Capital Announces $2.6 Million IsoRay Offering 2H. D. Smith and Adventist Health System Sign Prime Vendor Agreement 2H. D. Smith and Adventist Health System Sign Prime Vendor Agreement 3
... The USS Sports Medicine™ AnchorSew™ 3 mm is ... the USS Sports Medicine ArthroSew suturing device to ... repair device is implanted into a prepared hole ... soft tissue. The soft tissue anchors are made ...
... of anchor is generally used when ... This 2.9mm anchor is packaged sterile ... or 2-0) and needles. Although pre-drilling ... the Mini Harpoon®, 1.6mm & 1.8mm ...
... USS Sports Medicine™ Ogden™ Sterile Anchor is ... tissue to bone using sutures. The device ... the bone and is used to reattach ... from Titanium (6AL4V ELI) alloy which conforms ...
The MINI-TAG™ instrument systems are indicated for ulnar collateral ligament repair, scapholunate dissolution, flexor avulsions, and carpometa-carpal arthroplasty....
Medicine Products: