Navigation Links
Diabetic potential to create own insulin
Date:6/14/2010

Researchers from the Peninsula Medical School, working in collaboration with colleagues from Glasgow Royal Infirmary and the University of Brighton, have used a unique collection of pancreas specimens taken from patients who died soon after diagnosis of type 1 diabetes to show that they respond to the ongoing process of destruction by inducing their islet cells to proliferate.

The research is published on-line at Diabetologia and is funded by Juvenile Diabetes Research Foundation.

The findings are important because, until now, it has been generally believed that, in humans, beta cells divide only very infrequently after the first year or so of life and that they do not readily proliferate once type 1 diabetes is diagnosed. By studying the same unique collection of pancreas specimens that last year led the research team to conclude that some cases of type 1 diabetes may have a viral cause, this current study presents evidence that there is a 10-fold increase in islet cell replication in patients recently diagnosed with type 1 diabetes. A similar response had been seen previously in an animal model of type 1 diabetes by a member of the team, Professor Adrian Bone (University of Brighton) but it was not known if accelerated β-cell replication also occurs in human patients.

The factors that trigger the replication process in patients with type 1 diabetes are still unclear, although the study shows a correlation with the infiltration of immune cells (which suggests that an immune mediator is likely to be involved).

The results of the research offer the hope that, in future, it might be possible to encourage a newly diagnosed type 1 diabetes patient's own beta cells to reproduce as a means of replacing those being destroyed by the disease. The development of such a therapy could mean that some patients with type 1 diabetes would be able to produce their own insulin for a longer period, thereby reducing the need for pha
'/>"/>

Contact: Andrew Gould
andrew.gould@pms.ac.uk
44-139-268-6107
The Peninsula College of Medicine and Dentistry
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Glucose Tattoo Could Track Blood Sugar Levels for Diabetics
2. Aspirin recommendations changed for many younger diabetic patients
3. Caring for Diabetic Pets Helps Humans Get Healthier
4. Experts Advise At-Risk Diabetics to Begin Daily Aspirin Later
5. Frequent Doctor Visits Help Diabetics Control Blood Pressure
6. Pig Pancreas Cells Help Type 1 Diabetics
7. Healthy Pre-Diabetics Still Face Heart Disease Threat
8. Drug a New Treatment Option for Diabetic Eye Disease
9. Tight Blood Sugar Control May Not Harm Diabetics
10. High-Dose Vitamin B Risky for Diabetics With Kidney Disease
11. Comparative-effectiveness study confirms new treatment for diabetic macular edema
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... Top medical tourism firm, VisitandCare.com ... the Dominican Republic to benefit from the experience of ... the medical tourism industry upside-down and becoming a choice ... services becoming the central influence. , “Trust is ... are not only attracted to low-cost surgical enhancement, but ...
(Date:3/27/2015)... 27, 2015 The report “CountryFocus ... an essential source of information on and analysis ... Germany. Germany’s increasingly elderly population and its associated ... market. In 2013, the elderly accounted for 27.1% ... Compound Annual Growth Rate (CAGR) of 1.2% to ...
(Date:3/27/2015)... March 27, 2015 DrugDev announced company ... Easy was named to the 2015 Philadelphia Business Journal ... list spotlights 40 dynamic, up-and-coming leaders less than 40 ... involvement. Winners are honored at an awards program in ... Philadelphia Business Journal. , Lyn Kremer, Publisher of the ...
(Date:3/27/2015)... According to Health Day , ... Neonatal Abstinence Syndrome (NAS) are causing alarm for Florida ... withdrawal process for a month of their lives- and ... and vomiting. The condition is precipitated by drug use ... treatment (and employing medically assisted drug treatment) will also ...
(Date:3/27/2015)... 2015 California’s ongoing worst ever drought, ... and the United States Northeast, are both manifestations of ... atmosphere is creating changes in the atmosphere’s “energy balance,” ... former NASA researcher, speaking on the Sharon Kleyne Hour™ ... only a warmer and dryer global climate but also ...
Breaking Medicine News(10 mins):Health News:Dominican Republic Plastic Surgery Provider Turning Medical Tourism Upside-Down 2Health News:Dominican Republic Plastic Surgery Provider Turning Medical Tourism Upside-Down 3Health News:Germany Healthcare, Regulatory and Reimbursement Landscape Market Research Report Available at RnRMarketResearch.com 2Health News:Germany Healthcare, Regulatory and Reimbursement Landscape Market Research Report Available at RnRMarketResearch.com 3Health News:Germany Healthcare, Regulatory and Reimbursement Landscape Market Research Report Available at RnRMarketResearch.com 4Health News:DrugDev Founder Melissa Easy is 2015 Philadelphia Business Journal 40 Under 40 Honoree 2Health News:In Florida Only 10% of Pregnant Mothers Are Referred to Drug Rehab Despite Testing Positive for Narcotics 2Health News:California Drought, Boston Blizzards Both Attributed to Global Climate Change Reports Climatologist to Fresh Water Advocate 2Health News:California Drought, Boston Blizzards Both Attributed to Global Climate Change Reports Climatologist to Fresh Water Advocate 3
... , , SALT LAKE ... it has added 10 new sales representatives to its nationwide direct sales ... , , "We,re thrilled to be adding so ... vice president of sales and marketing at Dynatronics. "This is just ...
... , , EMERYVILLE, Calif., ... ) today announced that it will webcast an investor briefing ... Time. Speakers will review clinical data for Nexavar in breast ... 34th European Society for Medical Oncology (ESMO) Multidisciplinary Congress in ...
... , , C.S. Mott Children,s Hospital ... to have their children vaccinated against H1N1 flu, despite higher disease risk; ... ANN ARBOR, Mich., Sept. 24 With schools back in session, H1N1 ... children. A new vaccine against H1N1 flu -- strongly recommended for kids ...
... , , SAN ... company discovering and developing a new class of naturally occurring ... in Tokyo on Tuesday October 6. Jeff Watkins, CEO of ... product engine, and lead program based on naturally occurring resected ...
... N.J., Sept. 24 Marketing Technology Solutions , ... QualityHealth.com , has today filed a lawsuit alleging that ... misappropriated trade secrets and other confidential information by utilizing MTS-copyrighted online ... a health website owned and operated by MediZine. , , ...
... Singapore and Washington DC (September 24, 2009) There is clear ... cancer, according to a study published in the current issue ... The article "Lifestyle Interventions in the Prevention and Treatment ... common forms of cancer (lung, colorectal, breast, prostate and skin) ...
Cached Medicine News:Health News:Dynatronics Expands Nationwide Direct Sales Force by 25 Percent 2Health News:H1N1 Flu: Are Parents Underestimating Risk to Kids? 2Health News:H1N1 Flu: Are Parents Underestimating Risk to Kids? 3Health News:H1N1 Flu: Are Parents Underestimating Risk to Kids? 4Health News:aTyr Pharma to Present at Japan Biopharma Partnering Conference 2Health News:MediZine Named in Intellectual Property Lawsuit Filed by Marketing Technology Solutions 2
(Date:3/27/2015)... 2015  Holographic Optical Technologies of Augusta, ... medical imaging, is entering the world of consumer electronics ... April 20 th , 2015, the campaign will introduce ... and 22-inch displays will allow consumers to view fully ... In addition to the two displays, the company will ...
(Date:3/27/2015)... , March 27, 2015 A new report from ... America – Chile , ... are top targets for IVD firms.  The healthcare research firm ... into IVD strategies for the Latin American continent with a ... globally distributed supply operations. However, the country,s regional economic clout ...
(Date:3/27/2015)... Report Details  New study shows ... What does the future hold for top companies ... new report shows you potential revenues to 2025, assessing ... 242-page report provides 185 tables, charts, and graphs. Discover ... future market prospects. Our new study lets you assess ...
Breaking Medicine Technology:Holographic Optical Technologies brings cutting-edge holograms to consumer market through upcoming Kickstarter campaign 2Holographic Optical Technologies brings cutting-edge holograms to consumer market through upcoming Kickstarter campaign 3Kalorama: Beyond Brazil, Latin American IVD Market Grows 2Kalorama: Beyond Brazil, Latin American IVD Market Grows 3Kalorama: Beyond Brazil, Latin American IVD Market Grows 4Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 2Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 3Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 4Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 5Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 6Pharma Leader Series: Top 25 Ophthalmic Drug Manufacturers 2015-2025 7
For the quantitative determination of alkaline phosphatase in human serum....
Auto LDL-Cholesterol, automated analyzer test kits....
Storage temperature: 15 - 30C, linearity: 0 - 20 mg/dL, expected value: male: 3.0 - 7.0 mg/dL and female: 2.2 - 6.2 mg/dL. Available with calibrator and number of tests 125....
For the quantitative determination of Uric Acid in serum. Linearity: 25 mg/dl....
Medicine Products: