Navigation Links
Diabetic drug could help prevent the spread of cancer
Date:5/31/2011

A protein activated by certain drugs already approved for treating Type II diabetes may slow or stop the spread of breast tumors.

"It's possible that these diabetes drugs could ultimately be used, alone or in combination with existing chemotherapeutic drugs, to treat some forms of breast cancer," says Chris Nicol, an assistant professor in the Department of Pathology and Molecular Medicine and Queen's University Cancer Research Institute.

As a diabetes treatment, this class of drug activates a protein that helps to maintain normal fat and sugar metabolism. Recently this protein has also been found to decrease malignancy and metastatic spread of some forms of breast cancer tumors.

In earlier research, Dr. Nicol found that removing or reducing this particular protein in specific cell types such as breast cells increased the likelihood of cancer developing and the cancer was often more prone to malignancy and spreading.

This finding suggests that women who have reduced activity of this protein in their breast or associated cells and who are exposed to risk factors such as environmental or chemical pollutants or a poor (high fat) diet are more likely to develop more tumors. Furthermore, these tumors are more likely to spread throughout the body.

"We know obesity is a risk factor for many other diseases, including diabetes and breast cancer," explains Dr. Nicol. "With the current obesity epidemic, our bodies have more circulating fats than we can normally handle, and this protein may be unable to exert its anti-cancer effects without some assistance."

Dr. Nicol has received $438,000 from the Canadian Breast Cancer Foundation for further investigating how environmental chemicals and poor diets contribute to breast cancer risk, and determining how this protein acts to prevent breast cancer progression. He also hopes to identify whether foods containing a natural version of activators for this protein could be used as a dietary supplement for breast cancer patients.


'/>"/>

Contact: Christina Archibald
christina.archibald@queensu.ca
613-533-2877
Queen's University
Source:Eurekalert  

Related medicine news :

1. Diabetics Twice as Likely to Have Hearing Loss; Florida HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March
2. Diabetics Twice as Likely to Have Hearing Loss; Massachusetts HearUSA Centers to Offer Free Hearing Screening and Diabetes Video in March
3. Hormone Outperforms Insulin in Diabetic Mice
4. Intense Cholesterol, Blood Pressure Therapies Dont Help Type 2 Diabetics
5. Wound Management Technologies, Inc. Announces Conference Plans and Clinical Data Presentation at Leading Diabetic Foot Conference
6. Prodigy Re-Launches Syringe-Filling System for Blind and Low-Vision Diabetics
7. Accepting Help Improves Survival Among Diabetics
8. Diabetics Face Higher Death Risk After Cancer Surgery
9. Women, Diabetics Fall Fast Into Medicare Doughnut Hole
10. Discovery could help diabetics and others with slow-to-heal wounds
11. Diabetic Sock Company to Donate a Pair of Socks for Every Pair Sold to U.S. Homeless
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Diabetic drug could help prevent the spread of cancer
(Date:5/26/2017)... ... May 26, 2017 , ... Boar’s Head Brand®, ... recipes for Memorial Day entertaining that are sure to satisfy your guests’ flavor ... sliced meats and cheeses featured in these refreshingly balanced recipes are packed with ...
(Date:5/26/2017)... Bradley, Illinois (PRWEB) , ... May 26, 2017 , ... ... , The community, which is located on more than four acres of land at ... their independence. , The 103,000 square-foot building includes 125 studio and one-bedroom apartments. ...
(Date:5/26/2017)... ... May 26, 2017 , ... Centennial-based BluSky Restoration Contractors ... its 14th Annual Clays for Kids fundraiser, to be held Friday, Sept. 22, ... , As part of BluSky’s partnership with The Adoption Exchange, BluSky will also ...
(Date:5/24/2017)... Yorba Linda, Ca (PRWEB) , ... May 24, ... ... discriminating between effects and background. Understanind and choosing the most appropriate instruments for ... will prove critical in research finding. This webinar will focus on innovations in ...
(Date:5/24/2017)... , ... May 24, 2017 , ... Dr. Manju R. ... ClearCorrect orthodontics, with or without a referral. Dr. Kejriwal understands the emotional ... offers convenient, clear braces in Cincinnati, OH. Patients no longer need to feel the ...
Breaking Medicine News(10 mins):
(Date:5/11/2017)... TORONTO , May 11, 2017  Thornhill ... ) has been awarded an $8,049,024 USD five-year, ... Defense through the Canadian Commercial Corporation (CCC) ( ... Field Anesthesia Systems to administer general anesthesia to ... environment.  "The US Marine Corps have ...
(Date:5/10/2017)... 2017 CSSi, the global leader in patient ... industry, is proud to announce the launch of its ... features both enriched content and a customized layout that ... company,s already well-established position as the top global patient ... many months of hard work, we are delighted to ...
(Date:5/8/2017)... -- MACRA replaces the outdated sustainable growth rate ... Black Book Research crowdsource-surveyed 8,845 physician practices from February ... for MIPS Compliance Technology is Booming ... or more clinicians seek to buy Merit-Based Incentive Payment ... of the changes, the hunt is on for the ...
Breaking Medicine Technology: