Navigation Links
Diabetes treatment may also provide protection against endometrial cancer
Date:4/5/2011

Research led by Warwick Medical School at the University of Warwick has found that Metformin, a drug treatment used to treat diabetes and also in women with Polycystic vary syndrome (PCOS), may potentially provide protection against endometrial cancer.

Endometrial cancer is the most common malignancy of the female genital tract and the fourth most common cancer in women in the UK and the US. Up to a third of PCOS women also have endometrial hyperplasia which, in turn predisposes these women to endometrial cancer. PCOS affects 5%-10% of women of reproductive age, where Metformin ameliorates insulin resistance and hyperinsulinemia in these women, but also long-term use of Metformin improves ovulation and menstrual cycle regularity.

Recent research has found that Metformin has anti-cancer properties e.g. in breast cancer. Given that insulin resistant states, e.g. obesity, diabetes and PCOS are more at risk of developing endometrial cancer, the Warwick researchers studied the effects of metformin treatment on endometrial cancer cells. The researchers used serum from control and PCOS (before and after metformin treatment) subjects and carried out basic scientific experiments on endometrial cancer cells. The experiments revealed a decrease in endometrial cancer cell invasiveness in sera from metformin treated PCOS women.

The researchers found that serum samples from PCOS women who had completed the 6 month course of Metformin the rate of spread of endometrial cancer cells was around 25% lower than in the serum samples from PCOS women who had not started that treatment.

The principal investigators, Dr Harpal Randeva and Dr Bee K Tan, at Warwick Medical School said: "We are very excited about our findings, which reveal the significant impact of Metformin therapy use on human endometrial cancer cells. However, it is prudent that further research to explore if Metformin would actually be beneficial clinically as adjuvant ther
'/>"/>

Contact: Dr. Harpal S. Randeva
Harpal.Randeva@warwick.ac.uk
44-247-657-2552
University of Warwick
Source:Eurekalert  

0

GOOD

Page: 1 2

Related medicine news :

1. Add Cancer to Health Risks of Diabetes: Study
2. Avoiding or controlling diabetes may reduce cancer risk and mortality
3. Bariatric surgery reduces long-term cardiovascular risk in diabetes patients
4. Bariatric surgery highly cost-effective treatment for type 2 diabetes in the obese
5. International Diabetes Federation supports surgery to treat diabetes
6. Nick Jonas Lives Large, Despite Diabetes
7. Actos Cut Risk of Prediabetes Becoming Diabetes in Study
8. Study Ties Asthma to Higher Odds for Diabetes, Heart Disease
9. Metabolite levels may be able to improve diabetes risk prediction
10. Analysis Confirms Diabetes Drug May Harm the Heart
11. Diabetes Surgery 2nd World Congress
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Diabetes treatment may also provide protection against endometrial cancer
(Date:5/18/2013)... 18, 2013) There are significant cost and ... to diagnose or treat gastrointestinal problems, according to ... , A study by New York Presbyterian Hospital ... testing may substantially reduce the cost and risk ... is believed to affect nearly 25 percent of ...
(Date:5/18/2013)... 18, 2013 Today, Zane Benefits, ... agents’ role in Marketplaces . Zane Benefits, which ... sponsored health benefits, is the leader in health ... health reimbursement arrangements . , According to Zane ... Services (HHS) recently released a much-anticipated statement and ...
(Date:5/18/2013)... York, NY (PRWEB) May 18, 2013 After ... consistent efforts, SizeItUp formally announced the integration of ... redesigned 2012 Hyundai Genesis is set to stun the automobile ... and style. 2012 Hyundai Genesis is marked as the latest ... and heads the vehicles lined up for the year 2013. ...
(Date:5/18/2013)... Although obesity is associated with an increased risk ... esophageal adenocarcinoma, a type of esophageal cancer, is stronger ... on Cancer.gov, last reviewed in January 2012, overweight ... those of normal and healthy weight to develop this ... cancer is not well understood, it is now thought ...
(Date:5/18/2013)... Show And Go Training, the culmination of Eric ... that is all about is getting results in the fastest ... http://ShowAndGoTrainingReview.com ’s Stan Stevenson, prompting an investigative review. , ... phase system” designed to make you faster, stronger, fitter and ... out in the gym. The training manual and exercise video ...
Breaking Medicine News(10 mins):Health News:New research identifies practice changes to improve value and quality of GI procedures 2Health News:Zane Benefits Publishes New Information on Insurance Agents’ Role in Marketplaces 2Health News:Zane Benefits Publishes New Information on Insurance Agents’ Role in Marketplaces 3Health News:Zane Benefits Publishes New Information on Insurance Agents’ Role in Marketplaces 4Health News:Renowned Rim Fitments Provider SizeItUp Launched Database Integrations for the 2012 Hyundai Genesis 2Health News:hCGtreatments / Diet Doc Hcg Diets & Weight Loss Plans Announces New Prescription Hcg Diet Plans Designed to Trim Inches and Thus Reduce the Risk of Esophageal Cancer 2Health News:hCGtreatments / Diet Doc Hcg Diets & Weight Loss Plans Announces New Prescription Hcg Diet Plans Designed to Trim Inches and Thus Reduce the Risk of Esophageal Cancer 3Health News:Show And Go Training: Review Examining Eric Cressy's Workout Program Revealed 2
... Inc. (Nasdaq: VNUS ), a leading provider of ... disease, today,announced that it presented at the William Blair ... on October 3, 2007, at the New York,Palace Hotel ... the VNUS presentation webcast is available on the,corporate website ...
... SAN DIEGO, Oct. 3 Anadys Pharmaceuticals,Inc. (Nasdaq: ... BIO,InvestorForum 2007 on Wednesday, October 10, 2007, at 11:45 ... at The Palace Hotel in San,Francisco. Steve Worland, ... will present an overview of Anadys and an update ...
... A new Web site from Northwood,Health Systems has ... a five-year development effort in partnership with the best,Web ... perfect the,application of Web site technology," Northwood President and ... http://www.NorthwoodHealth.com, offers more than 1,000 accredited,continuing education courses ...
... NORCROSS, Ga., Oct. 3 Immucor, Inc. (Nasdaq:,BLUD), ... to,the blood transfusion industry, today reported financial results ... Revenue for the fiscal first quarter was ... in the same period last year. Of the ...
... Oct. 3 The patent lawsuit,by VNUS(R) Medical Technologies, ... Diomed, AngioDynamics and Vascular Solutions,is set to proceed to ... by both sides. In its motions VNUS had asked ... infringed the VNUS patents,while the defendants countered with their ...
... will work, experts say , WEDNESDAY, Oct. 3 (HealthDay ... help doctors determine the best chemotherapy for patients, U.S. ... tumors would be most likely to respond to standard ... has traditionally been a second-line therapy, based on gene ...
Cached Medicine News:Health News:Anadys Pharmaceuticals to Present at BIO InvestorForum 2007 2Health News:Immucor Announces Record Fiscal First Quarter Revenues 2Health News:Immucor Announces Record Fiscal First Quarter Revenues 3Health News:Immucor Announces Record Fiscal First Quarter Revenues 4Health News:Immucor Announces Record Fiscal First Quarter Revenues 5Health News:Immucor Announces Record Fiscal First Quarter Revenues 6Health News:Immucor Announces Record Fiscal First Quarter Revenues 7Health News:Immucor Announces Record Fiscal First Quarter Revenues 8Health News:VNUS Medical's Patent Lawsuit Against Laser Competitors to Proceed to Trial 2Health News:VNUS Medical's Patent Lawsuit Against Laser Competitors to Proceed to Trial 3Health News:Gene Tests Match Up Lung Tumors, Best Treatment 2
(Date:5/17/2013)... , May 17, 2013  Sony Biotechnology Inc. ... SP6800 Spectral Analyzer (SP6800).  Sony will be exhibiting and ... will be held at the San Diego ... California , from May 20 - 22.  ... analytical system, incorporating commercial audio-visual technologies into new and ...
(Date:5/17/2013)... 17, 2013  ConvaTec today announced that it will report its 2013 ... , CEO, and Ed Borkowski , CFO, will ... telephone. To participate in the conference call within the ... To participate in the conference call outside the U.S. and ... is 72195398. Participants should dial in 10 minutes prior to ...
(Date:5/17/2013)...  Boehringer Ingelheim will contribute to advancing the ... Thoracic Society International Conference (ATS 2013) in ... 22. Data will highlight research conducted ... chronic obstructive pulmonary disease (COPD) [Spiriva® HandiHaler® (tiotropium ... for asthma, idiopathic pulmonary fibrosis (IPF) and COPD. ...
Breaking Medicine Technology:Sony Biotechnology Inc.'s New Technology for Science Provides Researchers Results in Color 2Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 2Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 3Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 4Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 5Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 6Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 7Boehringer Ingelheim to Present 17 Abstracts at the Annual American Thoracic Society International Conference 8
... , , NEW YORK, ... of FairChoice Health, its campus health management service, in ... FairChoice Health empowers campus health officers to alert students ... track vaccination compliance. FairChoice Health is the first ...
... , , LONDON, July ... through a cancer treatment that changed her life -- and made history ... world to receive an injection of tumor-activated natural killer (TaNK) cells as ... the Royal Free Hospital in London recommended this experimental therapy after two ...
Cached Medicine Technology:Online H1N1 Management: FairChoice Helps Schools Respond to Infectious Disease on Campus 2British Woman Celebrates a Year of Living Cancer-Free 2British Woman Celebrates a Year of Living Cancer-Free 3British Woman Celebrates a Year of Living Cancer-Free 4
... Bird and Cronin, ... manufacturer of Patient Footwear, ... Patient Care Products. Our ... highest quality and available ...
AchilloTrain is a comfortable knitted support with a silicone insert alongside the Achilles tendon and under the heel. An additional heel cushion is provided for the unaffected foot. It is worn to tr...
DarcoGel™ Upper chamber is foam filled, conforms to calf; gel-filled lower chamber molds to the malleoli for a custom fit. Freeze the removable liner for cold therapy. One size. Fits left or ri...
... maintaining the ankle in functional alignment. Entire ... cushioning AliPlast™ foam liner. The cushioning air ... heel in a protective hammock, reducing ulceration ... bed from side-lying to supine. Only the ...
Medicine Products: