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Diabetes surgery summit consensus lays foundation for new field of medicine
Date:11/23/2009

r. Francesco Rubino, director of the gastrointestinal metabolic surgery program at NewYork-Presbyterian Hospital/Weill Cornell Medical College and associate professor of surgery at Weill Cornell Medical College. "The recommendations from the Diabetes Surgery Summit are an opportunity to improve access to surgical options supported by sound evidence, while also preventing harm from inappropriate use of unproven procedures."

The article in the Annals of Surgery, co-authored by the DSS organizers on behalf of 50 voting delegates, summarizes the mounting body of evidence showing that bariatric surgery effectively reverses type 2 diabetes in a high proportion of morbidly obese patients, sometimes within weeks or even days, well before these patients have lost a significant amount of body weight.

Dr. Rubino's experimental studies demonstrated that gastric bypass surgery can improve type 2 diabetes through direct anti-diabetic mechanisms and not solely as a result of weight loss, a finding that has been corroborated by other researchers with both experimental and human investigations. Based on these data, the 50 international delegates of the Rome summit achieved strong consensus that certain intestinal bypass operations engage anti-diabetes mechanisms beyond those related to reduced food intake and body weight.

"This and the remarkable clinical efficacy of gastrointestinal surgery justify considering it as a specific diabetes intervention, rather than viewing diabetes remission merely as a collateral effect of weight-loss surgery," says Dr. David E. Cummings, a leading endocrinologist at the Diabetes & Obesity Center of Excellence of the University of Washington in Seattle and senior author of the consensus document. "That understanding may also usher in a new era of drug discovery and development based on the identification of the metabolic pathways and mechanisms that drive the disease."

"The diabetes surgery consensus stateme
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Contact: Linda Kamateh
lib9027@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College
Source:Eurekalert

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