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Diabetes mellitus and mild cognitive impairment: Higher risk in middle age?
Date:9/2/2014

For this analysis, 560 participants diagnosed with MCI were compared with 1376 cognitively normal participants. Of participants with MCI, 289 had amnestic MCI and 271 had non-amnestic MCI.

Interestingly, diabetes mellitus type 2 was strongly associated with MCI as well as MCI subtypes, but only in the middle-aged group. Examination of differences by gender revealed a stronger association of diabetes with amnestic MCI in middle-aged women and by contrast a stronger association with non-amnestic MCI in middle-aged men.

These results suggest that middle-aged individuals with diabetes mellitus type 2 are particularly vulnerable to MCI, with gender specific effects on subtypes of MCI. This underlines the importance of high quality treatment of diabetes especially in middle age, not only because of cardiovascular damage, but also because it might help to prevent or delay cognitive decline.


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Contact: Astrid Engelen
a.engelen@iospress.nl
31-206-883-355
IOS Press
Source:Eurekalert

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