Navigation Links
Diabetes drug ups risk for bone fractures in older women
Date:2/10/2010

DETROIT A Henry Ford Hospital study finds women with type 2 diabetes who take a commonly prescribed class of medications to treat insulin resistance may be at a higher risk for developing bone fractures.

After taking a thiazolidinedione (TZD) for one year, women are 50 percent more likely to have a bone fracture than patients not taking TZDs, according to study results. And those at the greatest risk for fractures from TZD use are women older than 65.

"Older women are already at a higher risk of osteoporosis and osteoporosis-related fractures, which might explain why they appeared to be the most affected by TZDs," says study senior author L. Keoki Williams, M.D., MPH, Center for Health Services Research and Department of Internal Medicine at Henry Ford Hospital.

The study one of the largest groups to examine the longitudinal relationship between TZD use and fractures appears in this month's issue of The Journal of Clinical Endocrinology & Metabolism.

TZDs such as pioglitazone and rosiglitazone help keep blood glucose levels on target by decreasing insulin resistance and making body tissues more sensitive to insulin's effects. TZDs also cut down on the amount of glucose made by the liver in patients with type 2 diabetes.

But in recent years, TZDs have been linked to bone loss and increasing fracture risk. Complicating matters, type 2 diabetes and insulin use are also associated with an increased risk for fractures.

To determine the relationship between TZD use and fracture risk in patients with type 2 diabetes, Dr. Williams and his colleagues conducted a retrospective study from Jan. 2, 2000 to May 31, 2007 of 19,070 Henry Ford patients. Among the study group, 9,620 were women and 9,450 were men.

During the study period, 4,511 patients had at least one prescription fill for a TZD. The researchers used electronically maintained medical claims data to identify non-traumatic bone fractur
'/>"/>

Contact: Krista Hopson
khopson1@hfhs.org
313-874-7207
Henry Ford Health System
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Adverse housing conditions contribute to diabetes risk
2. RAND finds cases of undiagnosed diabetes drop sharply
3. UCLA researchers identify markers that may predict diabetes in still-healthy people
4. Diabetes appears to increase risk of death for patients with acute coronary syndromes
5. Discovery of sugar sensor in intestine could benefit diabetes
6. Despite overeating, morbidly obese mice gain protection against diabetes
7. Heart Attack Boosts Diabetes Risk
8. Obesity Doesnt Always Equal Diabetes
9. Sugary Sodas High in Diabetes-Linked Compound
10. Treating diabetes during pregnancy can break link to childhood obesity
11. Treating Diabetes During Pregnancy Could Lead to Thinner Kids
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/26/2014)... December 26, 2014 “Many people become ... personal injury claim issues and phone calls with insurance ... an article featuring their free eBook on pedestrian ... eBook on pedestrian and bicycle auto accident claims assures ... fully capable of professionally handling their case while they ...
(Date:12/26/2014)... December 26, 2014 Parker & ... the best in heating, cooling and plumbing contractor ... hour emergency services in 2014 with regard to ... that Arizona is known for its incredibly hot ... understands the intricacies and details of a wide ...
(Date:12/25/2014)... The report “Nintedanib (Colorectal Cancer) ... on the current treatment landscape, unmet needs, current ... market. Stivarga is a drug which is used ... Boehringer Ingelheim is developing nintedanib (BIBF-1120), an orally ... CRC in the US, Europe, and Japan. The ...
(Date:12/25/2014)... December 26, 2014 Recently, iFitDress.com, the popular ... women, has announced its new selection of black one-shoulder ... on sale now; they are available at discounted prices, up ... “The promotion will last for three weeks only. You know, ... Those who are interested in our new items can visit ...
(Date:12/25/2014)... 2014 BambooFlooringChina.com sells many bamboo products ... flooring. Today, the company announces big discounts on ... and colors. , BambooFlooringChina.com is the world’s leader in ... is valid until Jan. 20, 2015. , The bamboo ... with a natural thread. All the bamboo strips for ...
Breaking Medicine News(10 mins):Health News:Guide to Handling Pedestrian and Bicycle Accidents Released By The Jones Firm, Featured in Recent Article 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:iFitDress.com: Black One-Shoulder Cocktail Dresses for 2015 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... By Jenifer Goodwin HealthDay Reporter , TUESDAY, ... be reduced if operating room staff borrowed team-building procedures ... A program that trained operating room workers to ... and to review what went right or wrong after ...
... By Jenifer Goodwin HealthDay Reporter , TUESDAY, ... before heart surgery suffered fewer heart attacks, stroke and ... had better survival rates, two new studies find. ... bypass, valve or other scheduled cardiac surgeries. Of those, ...
... 19, 2010A rare and deadly form of breast cancer ... is the focus of a new report from leading ... an unrecognized and misunderstood form of breast cancer. It ... has lower overall survival compared to other breast cancers. ...
... a child or a dog play is not a foreign sight. ... Apparently, they play, too. In fact, according to Gordon Burghardt, ... -- not just dogs, cats, and monkeys -- need a little ... juvenile reptiles for many years and never saw anything that I ...
... Reporter , MONDAY, Oct. 18 (HealthDay News) -- ... medical mistakes, ranging from an operation on the wrong ... a new study finds. To try to curb ... 2004 introduced a universal protocol for all hospitals, ambulatory ...
... and quality of life for older people, but is also ... The research will be presented today,s at the Scientific Program ... East-Africa Council of Ophthalmology (MEACO) Joint Meeting. Cataract surgery not ... but is also apparently a way to reduce the number ...
Cached Medicine News:Health News:Lessons From Flight Crews Can Help Surgical Teams Work Better 2Health News:Lessons From Flight Crews Can Help Surgical Teams Work Better 3Health News:Aspirin, Statins May Reduce Problems After Heart Surgery 2Health News:Aspirin, Statins May Reduce Problems After Heart Surgery 3Health News:Inflammatory breast cancer focus of new report 2Health News:UT professor defines play, discovers even turtles need recess 2Health News:Surgery on Wrong Patients, Surgical Sites Persists, Study Finds 2Health News:Surgery on Wrong Patients, Surgical Sites Persists, Study Finds 3Health News:Surgery on Wrong Patients, Surgical Sites Persists, Study Finds 4Health News:Cataract surgery saves lives, dollars by reducing auto crashes 2
(Date:12/24/2014)... Dec. 24, 2014 Soligenix, Inc. (OTCQB: ... company developing products that address unmet medical needs ... announced today that on December 24, 2014 it ... The Company raised approximately $2.3 million in ... use the net proceeds from the offering to ...
(Date:12/24/2014)... Dec. 24, 2014  Diplomat Pharmacy, Inc. (NYSE: ... is proud to announce Jennifer Hagerman , Pharm.D., ... will take office as the president of the Michigan ... ceremony will take place Feb. 28, 2015, at the ... at the Renaissance Center in Detroit, Michigan ...
(Date:12/24/2014)... Dec. 23, 2014 PuraMed BioScience®, Inc., (OTC ... (OTC) medicinal and healthcare products, announced it received the ... a hemp-based, advanced headache relief product, for planned distribution ... Colorado , Washington State ... With the MigraPure H Advanced headache relief gel formulation ...
Breaking Medicine Technology:Soligenix Announces Closing of Public Offering of Units 2Soligenix Announces Closing of Public Offering of Units 3Diplomat's senior director of education and quality to be inducted as 2015 president of the Michigan Pharmacists Association 2Diplomat's senior director of education and quality to be inducted as 2015 president of the Michigan Pharmacists Association 3PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 2PuraMed BioScience Nears Final Stages Needed for Distribution of MigraPure H 3
... 2011  IRIDEX Corporation (Nasdaq: IRIX ) today ... 10 years demonstrates the safety and efficacy of MicroPulse ... the retina tissue damage associated with conventional laser therapy.  ... and Prevention, DME, a swelling of retinal tissue, is ...
... Reportlinker.com announces that a new market ... Global Medical Ultrasound ... http://www.reportlinker.com/p098401/Global-Medical-Ultrasound-Equipment-Industry.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Medical_I This report analyzes ... in US$ Million by the following End-Use ...
Cached Medicine Technology:10-Year Study Demonstrates IRIDEX MicroPulse™ Laser Therapy Safe, Effective for Patients with Diabetic Macular Edema 210-Year Study Demonstrates IRIDEX MicroPulse™ Laser Therapy Safe, Effective for Patients with Diabetic Macular Edema 3Global Medical Ultrasound Equipment Industry 2Global Medical Ultrasound Equipment Industry 3Global Medical Ultrasound Equipment Industry 4Global Medical Ultrasound Equipment Industry 5Global Medical Ultrasound Equipment Industry 6Global Medical Ultrasound Equipment Industry 7Global Medical Ultrasound Equipment Industry 8Global Medical Ultrasound Equipment Industry 9Global Medical Ultrasound Equipment Industry 10Global Medical Ultrasound Equipment Industry 11Global Medical Ultrasound Equipment Industry 12Global Medical Ultrasound Equipment Industry 13Global Medical Ultrasound Equipment Industry 14Global Medical Ultrasound Equipment Industry 15Global Medical Ultrasound Equipment Industry 16Global Medical Ultrasound Equipment Industry 17Global Medical Ultrasound Equipment Industry 18Global Medical Ultrasound Equipment Industry 19Global Medical Ultrasound Equipment Industry 20Global Medical Ultrasound Equipment Industry 21Global Medical Ultrasound Equipment Industry 22Global Medical Ultrasound Equipment Industry 23Global Medical Ultrasound Equipment Industry 24Global Medical Ultrasound Equipment Industry 25
... Pick one of our pipettors up and ... and ejector positionsright where they should beeven if ... designed to help avoid repetitive stress injuries caused ... The Palm Of Your Hand Start dispensing ...
... for Unparalleled Comfort Pick one of our ... Notice the trigger and ejector positionsright where they ... pipettors are ergonomically designed to help avoid repetitive ... Productivity In The Palm Of Your Hand ...
... best value in high performance electronic pipetting!, ... lightweight design reduce hand fatigue and strain ... tip ejector , Color coding for easy ... for greater performance use Hamilton AdvanTip Low ...
... Pipette is ideal for all liquid handling ... ergonomically-placed operating buttons, and various dispensing techniques ... diluting make this a lab favorite. It ... manual pipette without any adverse effects on ...
Medicine Products: