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Diabetes and Elevated Levels of Cholesterol Linked to Faster Cognitive Decline in Alzheimer's Patients
Date:3/6/2009

ize that the link between vascular risk factors and faster cognitive decline in patients with Alzheimer's disease may occur because vascular diseases may increase oxidative stress or activate inflammation in the brain, thereby triggering the production of amyloid, and/or triggering the formation of neuron tangles - known as neurofibrillary tangles - which are believed to be a primary cause of Alzheimer's disease.

Dr. Stern and his colleagues are continuing to study the basis of the links between vascular risk factors and Alzheimer's disease using epidemiologic and imaging approaches.

Columbia University Medical Center provides international leadership in basic, pre-clinical and clinical research, in medical and health sciences education, and in patient care. The medical center trains future leaders and includes the dedicated work of many physicians, scientists, public health professionals, dentists, and nurses at the College of Physicians and Surgeons, the Mailman School of Public Health, the College of Dental Medicine, the School of Nursing, the biomedical departments of the Graduate School of Arts and Sciences, and allied research centers and institutions.

Established in 1767, Columbia's College of Physicians and Surgeons was the first institution in the country to grant the M.D. degree and is now among the most selective medical schools in the country. Columbia University Medical Center is home to the most comprehensive medical research enterprise in New York City and state and one of the largest in the United States. Columbia University Medical Center is affiliated with NewYork-Presbyterian Hospital, the nation's largest not-for-profit hospital provider. For more information, please visit www.cumc.columbia.edu.

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