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Diabetes Patients That Bring Glucose Meters to Doctor Visits Have Better Control Over Their Disease
Date:6/19/2013

of adding another medication.”

The team reviewed data on 500 adult patients at the Mount Sinai Diabetes Center and determined that 30 percent of the patients (almost all insulin-treated) brought glucose meters to their visits. “Hand-written glucose logs can be misleading,” said Gillian Boyd-Woschinko, MD, Chief Endocrine Fellow at Mount Sinai and lead author of the study. “Past research has shown then when comparing hand written logs to meter data, it can be inaccurate due to under-reporting and over-reporting. Both occur as a result of human error, the desire to please the physician, and lack of understanding of the utility of accurate data. We encourage all patients to bring their blood glucose meters to their appointments, so we can download them.”

  •     Prostatic Acid Phosphatase in Prostate Cancer Bone Metastases: Rank Ligand as a Mediator

Levels of prostatic acid phosphatase (PAP), the oldest tumor marker, are elevated in men with prostate cancer (PCa) bone metastases, according to research presented by Alice C. Levine, MD, Professor of Medicine in the Division of Endocrinology, Diabetes and Bone Diseases at the Icahn School of Medicine at Mount Sinai and her team in a highlighted poster session. According to Dr. Levine, PCa has a tendency to spread to the bone where it becomes incurable and blood PAP levels are higher in men with PCa bone metastases.

“Currently, there are no curative therapies for this stage of the disease,” said Dr. Levine. “Our study could have wide-ranging clinical applications for men with advanced PCa that has spread to bone.”

Researchers studied two PCa cell lines and a mouse preosteoblast (OB) line. All three cell lines expressed measurable amounts of two proteins, RANK Ligand (RANKL) and Osteoprotegerin (OPG) mRNA/protein that are known to be essential regulators of bone formation and breakdown. The results suggested that PAP secreted
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