Navigation Links
Diabetes Drugs Avandia, Actos Tied to Fractures in Women
Date:2/15/2010

Those over 65 at greatest risk from thiazolidinedione use, study indicates

MONDAY, Feb. 15 (HealthDay News) -- Women who take diabetes drugs known as thiazolidinediones, which include Avandia and Actos, are at a greater risk of bone fractures, a new study finds.

Women who took a thiazolidinedione drug for a year were 50 percent more likely to suffer a bone fracture than patients who didn't take the drug, the researchers found. Women older than 65 were most vulnerable, with a 70 percent higher risk.

"Older women are already at a higher risk of osteoporosis and osteoporosis-related fractures, which might explain why they appeared to be the most affected," study senior author Dr. L. Keoki Williams, of the Center for Health Services Research at Henry Ford Hospital, said in a news release.

Thiazolidinedione drugs -- which include pioglitazone (Actos) and rosiglitazone (Avandia) -- help people with type 2 diabetes better control their blood sugar levels. The drugs work by lowering resistance to insulin and cutting the amount of glucose made by the liver.

But doctors have worried in recent years about reports linking the drugs to bone loss and higher risk of fractures.

The researchers studied 4,511 patients who filled at least one prescription for a thiazolidinedione between 2000 and 2007 at Henry Ford Hospital. Men were not found to be at higher risk of fracture in this study group, the study authors noted in the news release, although other recent research has suggested such a link.

The findings are published in the February issue of the Journal of Clinical Endocrinology & Metabolism.

The drugs "may put some patients at increased risk for other health issues, and I encourage patients to talk with their physician about other suitable options," Williams added.

More information

The U.S. National Library of Medicine has more about thiazolidinediones.



-- Randy Dotinga



SOURCE: Henry Ford Hospital, news release, Feb. 10, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Diabetes drug ups risk for bone fractures in older women
2. International Diabetes Federation awards $2 million to 9 global diabetes research projects
3. NACDD Receives Two-Year Grant From Merck & Co., Inc. to Improve Diabetes Education
4. Neighborhood socioeconomic status and diabetes
5. In a Cross-Country Comeback, Skier With Type 1 Diabetes Named to U.S. Olympic Team
6. Genome Mapped for Type 2 Diabetes
7. New study finds possible source of beta cell destruction that leads to Type 1 diabetes
8. New Website Giving Away Diabetes-Friendly Super Bowl Munchies Recipes to Tackle America's Toughest Health Problem
9. Scientists map out regulatory regions of genome, hot spots for diabetes genes
10. Diabetes patients rank health concerns differently than their doctors, U-M survey shows
11. Diabetes Drug Helps Dieting Teens Lose Weight
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/27/2017)... CA (PRWEB) , ... February 27, 2017 , ... ... muscle mass and overall body strength, which often leads to a host of ... Journal of the American Geriatrics Society discovered that good overall muscle ...
(Date:2/27/2017)... ... February 27, 2017 , ... Anahata Ananda ... Awakening, is happy to announce her “Spring Rejuvenation in Sedona” personally tailored ... customized retreats offer the winter-weary soul an excellent opportunity to come out of ...
(Date:2/27/2017)... ... February 27, 2017 , ... Elisa Guajardo Carothers is not your typical author. She ... to become a nun. Now, she writes about God, when she isn’t swimming as a ... and AD, Here is BS! (Before Satan),” she offers a comedic look at the dysfunctions ...
(Date:2/27/2017)... ... February 26, 2017 , ... Miro is the ultimate smart media ... system brings songs, movies, TV shows and much more apps for user exploration. Its ... An immersive view of 1280 x 720 provides crisp images with remarkable clarity and ...
(Date:2/27/2017)... (PRWEB) , ... February 27, 2017 , ... ... rehabilitation and alcohol treatment programs in British Columbia, Canada, at https://www.sunshinecoasthealthcentre.ca/ , ... its team. The new hire, Mackenzie Alsager, showcases the Centre's commitment to innovation ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... Research and Markets has announced the addition of the "Global ... report to their offering. ... The Global Wireless Health Market is poised to ... to reach approximately $330.5 billion by 2025. This industry ... segments on global as well as regional levels presented in the ...
(Date:2/24/2017)... , Feb. 24, 2017 Research and Markets ... & Trends - Industry Forecast to 2025" report to their offering. ... The Global Empty Capsules ... the next decade to reach approximately $2.9 billion by 2025. ... the given segments on global as well as regional levels presented in ...
(Date:2/24/2017)... 24, 2017 Research and Markets has announced the ... 2016" report to their offering. ... The latest research Dry eye Drugs Price Analysis and Strategies ... eye market. The research answers the following questions: ... their clinical attributes? How are they positioned in the Global Dry eye ...
Breaking Medicine Technology: