Navigation Links
Diabetes Drugs Avandia, Actos Tied to Fractures in Women
Date:2/15/2010

Those over 65 at greatest risk from thiazolidinedione use, study indicates

MONDAY, Feb. 15 (HealthDay News) -- Women who take diabetes drugs known as thiazolidinediones, which include Avandia and Actos, are at a greater risk of bone fractures, a new study finds.

Women who took a thiazolidinedione drug for a year were 50 percent more likely to suffer a bone fracture than patients who didn't take the drug, the researchers found. Women older than 65 were most vulnerable, with a 70 percent higher risk.

"Older women are already at a higher risk of osteoporosis and osteoporosis-related fractures, which might explain why they appeared to be the most affected," study senior author Dr. L. Keoki Williams, of the Center for Health Services Research at Henry Ford Hospital, said in a news release.

Thiazolidinedione drugs -- which include pioglitazone (Actos) and rosiglitazone (Avandia) -- help people with type 2 diabetes better control their blood sugar levels. The drugs work by lowering resistance to insulin and cutting the amount of glucose made by the liver.

But doctors have worried in recent years about reports linking the drugs to bone loss and higher risk of fractures.

The researchers studied 4,511 patients who filled at least one prescription for a thiazolidinedione between 2000 and 2007 at Henry Ford Hospital. Men were not found to be at higher risk of fracture in this study group, the study authors noted in the news release, although other recent research has suggested such a link.

The findings are published in the February issue of the Journal of Clinical Endocrinology & Metabolism.

The drugs "may put some patients at increased risk for other health issues, and I encourage patients to talk with their physician about other suitable options," Williams added.

More information

The U.S. National Library of Medicine has more about thiazolidinediones.



-- Randy Dotinga



SOURCE: Henry Ford Hospital, news release, Feb. 10, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Diabetes drug ups risk for bone fractures in older women
2. International Diabetes Federation awards $2 million to 9 global diabetes research projects
3. NACDD Receives Two-Year Grant From Merck & Co., Inc. to Improve Diabetes Education
4. Neighborhood socioeconomic status and diabetes
5. In a Cross-Country Comeback, Skier With Type 1 Diabetes Named to U.S. Olympic Team
6. Genome Mapped for Type 2 Diabetes
7. New study finds possible source of beta cell destruction that leads to Type 1 diabetes
8. New Website Giving Away Diabetes-Friendly Super Bowl Munchies Recipes to Tackle America's Toughest Health Problem
9. Scientists map out regulatory regions of genome, hot spots for diabetes genes
10. Diabetes patients rank health concerns differently than their doctors, U-M survey shows
11. Diabetes Drug Helps Dieting Teens Lose Weight
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... Prior Lake MN (PRWEB) , ... February 24, ... ... the launch of its newly designed TaskMate Go. Core benefits and advantages built ... grain finish and a stylish, functional look and feel. Ability to gain the ...
(Date:2/24/2017)... ... February 24, 2017 , ... Dr. Ronald E. ... announced the appointment of Peter A. Bell, DO, MBA, HPF, FACOEP-dist., FACEP, as ... beginning April 10. Dr. Bell comes to Liberty from the Ohio University Heritage ...
(Date:2/24/2017)... , ... February 24, 2017 , ... The narrative in ... Erik Schanssema ’s true account of his paramedic experiences. Schanssema describes the tragedies ... and his attempts to overcome them. , Schanssema, initially unsure of the career ...
(Date:2/24/2017)... ... February 24, 2017 , ... Indiana Fiber Network (IFN) President and CEO ... year. Dyer started as the Chairman of the Management Committee when IFN was ... corporation including the recruitment of investor/owners and development of the business plan. He ...
(Date:2/23/2017)... Austin, TX (PRWEB) , ... February 23, 2017 ... ... has announced an official 2017 partnership with The Jensie Gran Fondo of Marin. ... UVA and UVB rays with Thinksport’s broad-spectrum, mineral-based sunscreen. , “We are thrilled ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)...  This report analyzes the worldwide markets for Chiral ... Products: Intermediates, Analytical, and Others. The End Use ... Agrochemicals. The report provides separate comprehensive analytics for the ... , and Rest of World. Annual estimates and ... Also, a six-year historic analysis is provided for these ...
(Date:2/24/2017)... Research and Markets has announced the addition ... 2016" report to their offering. ... The latest research Urinary Incontinence Drugs Price ... in the global Urinary Incontinence market. The research answers the ... drugs marketed for Urinary Incontinence and their clinical attributes? How are ...
(Date:2/23/2017)... , Feb. 23, 2017  Cogentix Medical, Inc. (NASDAQ: ... markets innovative proprietary products for the urology market, will ... year ended December 31, 2016 before the market open ... Company will host a conference call and webcast to ... March 9, 2017 at 11:00 a.m. Eastern Time (10:00 ...
Breaking Medicine Technology: