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Diabetes Drug May Slow Eye Disease
Date:6/9/2008

average of 2.8 years of follow-up.

The study is published in the June issue of the journal Archives of Ophthalmology.

Rosiglitazone may delay progression of retinopathy by reducing formation of new blood vessels, the researchers said.

"However, because this study does not rigorously prove that rosiglitazone either reduces the incidence of proliferative diabetic retinopathy or prevents loss of visual acuity, and because there may be adverse effects from therapy, rosiglitazone treatment of patients with diabetes specifically to reduce these ophthalmic complications is not advocated at this time," they wrote.

Rosiglitazone can cause such adverse effects as fluid build-up, abnormal liver function test, and worsening of congestive heart failure.

"Determination of the full efficacy and clinical role of rosiglitazone in the treatment of proliferative diabetic retinopathy and other angiogenic conditions awaits confirmation of risks and benefits and possibly large-scale definitive studies," the researchers concluded.

More information

The National Eye Institute has more about diabetic retinopathy.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, June 9, 2008


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