Navigation Links
Diabetes Drug May Prevent Early Puberty in Young Girls
Date:6/17/2008

Metformin delayed first menstruation, cut body fat for those at risk of insulin resistance

TUESDAY, June 17 (HealthDay News) -- The diabetes drug metformin slows the onset of early puberty and reduces the risk of insulin resistance in girls at risk for both conditions, a Spanish study concludes.

"The findings indicate that we can slow down puberty. This is important, because when puberty is faster in girls, the appearance of menses occurs earlier, and this sequence of events may ultimately result in a shorter adult height," senior author Dr. Lourdes Ibanez, of the University of Barcelona, said in a prepared statement.

In addition, getting a first menstrual period before age 12 has been linked to an increased risk of breast cancer, and early puberty is a known risk factor for polycystic ovary syndrome, a common cause of infertility.

The study included 38 girls who had not yet reached puberty but developed pubic hair before the age of 8, which typically means they'll start puberty earlier than their peers. The girls in the study had another risk factor for early puberty: They'd been born small and experienced rapid catch-up growth during infancy, leading to increased belly fat. That put them at increased risk for insulin resistance, a risk factor for type 2 diabetes, according to background information in the study.

The girls were about 8 years old when they were enrolled in the study. They were divided into two groups of 19 - one that received no treatment , and one that received treatment with low-dose metformin once a day for four years.

Compared to the girls who received no treatment, the girls in the treatment group started puberty and menstruation later, gained about 50 percent less fat, and became less insulin resistant. The girls in the treatment group continued to grow taller, while most of the girls in the untreated group had already stopped growing.

The study was presented June 16 at the Endocrine Society's annual meeting, in San Francisco.

More information

The Nemours Foundation has more about puberty.



-- Robert Preidt



SOURCE: The Endocrine Society, news release, June 16, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Study Ties Herpes Virus to Emerging Form of Diabetes
2. Diabetes and Depression Go Hand-in-Hand
3. Diabetes Might Help Spur Hearing Loss
4. Current screening test for prediabetes in children misses the diagnosis too often
5. Some patients may not need insulin for long-term control of type 2 diabetes
6. Defeat Diabetes Foundation Announces Martial Arts Defeat Diabetes(R) Community Action Project(TM)
7. Do vaccines cause autism, asthma and diabetes?
8. Unique drug combination may hold the key to reversing Type I diabetes
9. USC physician Anne L. Peters receives American Diabetes Associations Distinguished Clinician Award
10. Diabetes Drug May Slow Eye Disease
11. Promising advances in islet cell transplants for diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... Calif. (PRWEB) , ... October 13, 2017 , ... Many ... dementia. However, many long-term care insurance companies have a waiver for care if the ... 90-day elimination period, when the family pays for care, is often waived, so the ...
(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids ... Milford, NJ. This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, ... run is geared towards children of all ages; it is a non-competitive, non-timed event, ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... and Agile Software Development, has been awarded a contract by the Center for ... Agreement (BPA) aims to accelerate the enterprise use of Agile methodologies in a ...
(Date:10/12/2017)... (PRWEB) , ... October 12, 2017 , ... ... advisory services for healthcare compliance program management, will showcase a range of technology ... Association for Assisted Living (NCAL) Convention and Expo to be held October 14–18, ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed ... consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has ... highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy ...
Breaking Medicine News(10 mins):
(Date:9/19/2017)... LOUISVILLE, Ky. , Sept. 19, 2017   ZirMed ... and predictive analytics, today announced that it has been ranked ... the Black Book™ Rankings 2017 User Survey. ZirMed ... software solution for large hospitals and medical centers over 200 ... in Black Book,s healthcare technology user survey history. ...
(Date:9/13/2017)... 13, 2017   OrthoAtlanta has been named the ... Host Committee (AFHC) for the 2018 College Football Playoff (CFP) ... at Mercedes-Benz Stadium in Atlanta, Georgia . ... "I,m In" campaign, participating in many activities leading up to, ... ...
(Date:9/12/2017)... 2017  ValGenesis Inc., the global leader in ... to announce the appointment of Dr. Ajaz ... of Directors and Chairman of Advisory Board beginning ... companies to manage their entire validation lifecycle process ... this process. Furthermore, ValGenesis VLMS enables rigorous compliance, ...
Breaking Medicine Technology: