Navigation Links
Diabetes Drug May Prevent Early Puberty in Young Girls
Date:6/17/2008

Metformin delayed first menstruation, cut body fat for those at risk of insulin resistance

TUESDAY, June 17 (HealthDay News) -- The diabetes drug metformin slows the onset of early puberty and reduces the risk of insulin resistance in girls at risk for both conditions, a Spanish study concludes.

"The findings indicate that we can slow down puberty. This is important, because when puberty is faster in girls, the appearance of menses occurs earlier, and this sequence of events may ultimately result in a shorter adult height," senior author Dr. Lourdes Ibanez, of the University of Barcelona, said in a prepared statement.

In addition, getting a first menstrual period before age 12 has been linked to an increased risk of breast cancer, and early puberty is a known risk factor for polycystic ovary syndrome, a common cause of infertility.

The study included 38 girls who had not yet reached puberty but developed pubic hair before the age of 8, which typically means they'll start puberty earlier than their peers. The girls in the study had another risk factor for early puberty: They'd been born small and experienced rapid catch-up growth during infancy, leading to increased belly fat. That put them at increased risk for insulin resistance, a risk factor for type 2 diabetes, according to background information in the study.

The girls were about 8 years old when they were enrolled in the study. They were divided into two groups of 19 - one that received no treatment , and one that received treatment with low-dose metformin once a day for four years.

Compared to the girls who received no treatment, the girls in the treatment group started puberty and menstruation later, gained about 50 percent less fat, and became less insulin resistant. The girls in the treatment group continued to grow taller, while most of the girls in the untreated group had already stopped growing.

The study was presented June 16 at the Endocrine Society's annual meeting, in San Francisco.

More information

The Nemours Foundation has more about puberty.



-- Robert Preidt



SOURCE: The Endocrine Society, news release, June 16, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Study Ties Herpes Virus to Emerging Form of Diabetes
2. Diabetes and Depression Go Hand-in-Hand
3. Diabetes Might Help Spur Hearing Loss
4. Current screening test for prediabetes in children misses the diagnosis too often
5. Some patients may not need insulin for long-term control of type 2 diabetes
6. Defeat Diabetes Foundation Announces Martial Arts Defeat Diabetes(R) Community Action Project(TM)
7. Do vaccines cause autism, asthma and diabetes?
8. Unique drug combination may hold the key to reversing Type I diabetes
9. USC physician Anne L. Peters receives American Diabetes Associations Distinguished Clinician Award
10. Diabetes Drug May Slow Eye Disease
11. Promising advances in islet cell transplants for diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/8/2016)... Plainsboro, NJ (PRWEB) , ... December 08, 2016 , ... ... patients, cancer centers and advocacy groups, has aligned with Upstage Lung Cancer in efforts ... In making the announcement, Michael J. Hennessy, Jr said, “CURE Media Group is honored ...
(Date:12/8/2016)... ... December 08, 2016 , ... SunView ... customers and employees that are both engaging and easy to use. Coming off ... the software company revealed today its plans to roll out new AI-powered self-service ...
(Date:12/8/2016)... Dallas, TX (PRWEB) , ... December 08, 2016 , ... ... to continue to be a convenient service for Texas, they are expanding their presence ... will involve a hiring spree that will bring new jobs to the Dallas and ...
(Date:12/8/2016)... ... 2016 , ... Vida Health, the digital health platform that pairs ... Canvas Ventures . Other investors include Nokia Growth Partners (NGP) and returning investor Aspect ... consumers who are managing chronic conditions or simply want to improve their ...
(Date:12/8/2016)... ... December 08, 2016 , ... ... serve communities in and around the greater Phoenix metropolitan region, is announcing a ... , The mission of the Homeless Youth Connection is to promote community awareness ...
Breaking Medicine News(10 mins):
(Date:12/8/2016)... Dec. 8, 2016  EIP Pharma, LLC ( ... proof-of-mechanism for neflamapimod (previously code named VX-745), with ... clinical trials that demonstrated significant Alzheimer,s disease relevant ... treatment) and Study 303 (6-week treatment) are the ... Alzheimer,s Disease (CTAD) scientific conference in ...
(Date:12/8/2016)... Research and Markets has announced the addition of the ... ... The global chromatography market to grow at a CAGR of 5.42% during ... prepared based on an in-depth market analysis with inputs from industry experts. ... coming years. The report also includes a discussion of the key vendors ...
(Date:12/8/2016)... -- Economic growth in the United States will continue in ... in their December 2016 Semiannual Economic Forecast. Expectations are ... in mid-2009, as indicated in the monthly ISM ® ... manufacturing sector is optimistic about growth in 2017, with ... the non-manufacturing sector indicates that 14 of its industries ...
Breaking Medicine Technology: