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Developing a cyberinfrastructure for comparative effectiveness in cancer research
Date:2/3/2010

Nearly four decades after President Richard Nixon declared a "War on Cancer," the disease still claims the lives of 560,000 Americans every year, despite an annual expenditure of $5 billion by the U.S. government on research to battle it.

Although much progress has been made since Nixon's call to action in 1971, cancer research is made increasingly difficult by the vast amount relevant data, which is only increasing as scientists discover new drugs and interventions and continue to evaluate their relative benefits, risks and costs.

Now researchers from the University of California, San Diego division of the California Institute for Telecommunications and Information Technology (Calit2) and the UCSD School of Medicine have been awarded $2.6 million over two years from the U.S. National Institutes of Health's National Cancer Institute (NCI) to prototype a cyberinfrastructure that would allow scientists to collect and interpret data from a variety of sources to compare the effectiveness of preventative measures, drugs, treatments and interventions.

The Cyberinfrastructure for Comparative Effectiveness Research (CYCORE) project for cancer research will be scalable, open-source and user-friendly. CYCORE will aggregate data from clinical trials, patient medical records, self-reported and objectively monitored social and behavioral data, data on cancer outcomes from regional cancer registries, and cost-benefit analyses.

"A unique aspect of CYCORE will be its focus on expanding the quality and types of data that can be incorporated into cancer comparative effectiveness studies," said Kevin Patrick, MD, a professor in UC San Diego's Department of Family and Preventive Medicine and the principal investigator for the Calit2 component of the project. "From the outset, a primary focus will be on tackling the problem of obtaining, in patients' homes, objective person-level data on behaviors such as adherence to cancer medications, diet,
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Contact: Doug Ramsey
dramsey@ucsd.edu
858-822-5825
University of California - San Diego
Source:Eurekalert

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