Navigation Links
Determining Who Will Respond to Brain Tumor Therapy
Date:6/23/2009

Blood biomarker, combined with MRI scan, helps predict outcome, study finds,,

TUESDAY, June 23 (HealthDay News) -- A new biomarker that may help predict whether someone with a brain tumor will respond to a given treatment has been identified by U.S. researchers.

Looking to see who would respond to anti-vascular endothelial growth factor therapy, they used MRIs to scan the brains of people with recurrent glioblastoma, or malignant brain tumors, after they took an experimental drug called cediranib. By measuring vascular normalization, the researchers were able to identify, even after a single dose, people who benefitted from the drug and those who did not.

People with a greater degree of vascular normalization had longer overall survival and longer progression-free survival, according to the phase 2 study, which included 31 people.

"We found that results from an advanced MRI scan taken just a day after starting treatment correlated with survival," Dr. A. Gregory Sorensen, an associate professor of radiology and health sciences and technology at Harvard Medical School and Massachusetts General Hospital, said in a news release. "Combining MRI with blood biomarkers did an even better job of identifying patients who best responded to treatment."

"If this approach is validated in larger studies, we could use these tools to keep patients on therapies that their tumors respond to and shift non-responders to other therapies much earlier," he added.

The study appears in the journal Cancer Research.

More information

The U.S. National Cancer Institute has more about brain tumors.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, June 23, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. NEJM Report Finds HPV Test More Effective Than Pap in Determining Cervical Cancer Risk
2. CSHL scientists make progress in determining how the brain selectively interprets sound
3. New method proposed for determining which patients should get treatment for colorectal cancer
4. New Method Proposed for Determining Which Patients Should Get Treatment for Colorectal Cancer
5. Determining genetic signature of lung tumors can help guide treatment
6. Fitness a Key Element in Determining Male Diabetics Longevity
7. PET/CT scan could be valuable noninvasive tool for determining stages of ovarian cancer
8. Past Earnings Play Role in Determining SSDI Benefits
9. Determining Valuations in Challenging Times
10. Gender is key factor in determining overall survival of lung cancer patients
11. Determining risk for pancreatic cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Determining Who Will Respond to Brain Tumor Therapy
(Date:3/24/2017)... ... 24, 2017 , ... Mlynarek Insurance Agencies, a Detroit area ... owners across eastern Michigan, is connecting with the Oxford/Orion FISH Food Pantry for ... The Oxford/Orion FISH Food Pantry works to ensure homeless, hungry, and underprivileged families ...
(Date:3/24/2017)... ... March 24, 2017 , ... ... that they are now offering treatments for sleep apnea and TMJ at their ... Sleep apnea , specifically the obstructive type, is increasingly being treated at ...
(Date:3/24/2017)... ... March 24, 2017 , ... Gastro Health ... partnership to prep patients for colonoscopy at the HyGIeaCare® Center that is to ... Miami, FL. , The HyGIeaCare® Prep, cleared by the U.S. Food ...
(Date:3/24/2017)... ... ... “End Time GPS”: a dauntless and enlightened study of the second-coming of ... creation of published author, Wesley Gerboth, a World War II veteran, with a highly-regarded ... at age ninety-one, he shares the Wisdom God bestowed upon him in this publication. ...
(Date:3/23/2017)... & Seattle, WA (PRWEB) , ... March 23, 2017 , ... ... health emergency and now estimates that there could be four million Zika-related cases in ... epidemics to date with numbers of US cases reported per year skyrocketing to an ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... Calif. , March 24, 2017 /PRNewswire/ ... epigenetics company, and Hamilton Robotics, Inc., who ... announced an ongoing collaboration that teams Zymo ... and RNA and DNA extraction products with ... already created optimized methods for microbiomics and ...
(Date:3/24/2017)... 2017   The Accreditation Council for Medical ... in the pharmaceutical industry has appointed Dr. ... newly formed scientific advisory board. Dr. Chin will ... first ever medical affairs think tank within the ... the ACMA, please visit  www.medicalaffairsspecialist.org .  Connect ...
(Date:3/24/2017)... Research and Markets has announced the addition of ... to their offering. ... IPF pipeline is very strong with a total of 97 drug candidates. ... and Sanofi are involved in the development of the IPF therapeutics. The ... Phase III stage, 15 are in Phase II stage, 12 are in ...
Breaking Medicine Technology: