Navigation Links
Determining Who Will Respond to Brain Tumor Therapy
Date:6/23/2009

Blood biomarker, combined with MRI scan, helps predict outcome, study finds,,

TUESDAY, June 23 (HealthDay News) -- A new biomarker that may help predict whether someone with a brain tumor will respond to a given treatment has been identified by U.S. researchers.

Looking to see who would respond to anti-vascular endothelial growth factor therapy, they used MRIs to scan the brains of people with recurrent glioblastoma, or malignant brain tumors, after they took an experimental drug called cediranib. By measuring vascular normalization, the researchers were able to identify, even after a single dose, people who benefitted from the drug and those who did not.

People with a greater degree of vascular normalization had longer overall survival and longer progression-free survival, according to the phase 2 study, which included 31 people.

"We found that results from an advanced MRI scan taken just a day after starting treatment correlated with survival," Dr. A. Gregory Sorensen, an associate professor of radiology and health sciences and technology at Harvard Medical School and Massachusetts General Hospital, said in a news release. "Combining MRI with blood biomarkers did an even better job of identifying patients who best responded to treatment."

"If this approach is validated in larger studies, we could use these tools to keep patients on therapies that their tumors respond to and shift non-responders to other therapies much earlier," he added.

The study appears in the journal Cancer Research.

More information

The U.S. National Cancer Institute has more about brain tumors.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, June 23, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. NEJM Report Finds HPV Test More Effective Than Pap in Determining Cervical Cancer Risk
2. CSHL scientists make progress in determining how the brain selectively interprets sound
3. New method proposed for determining which patients should get treatment for colorectal cancer
4. New Method Proposed for Determining Which Patients Should Get Treatment for Colorectal Cancer
5. Determining genetic signature of lung tumors can help guide treatment
6. Fitness a Key Element in Determining Male Diabetics Longevity
7. PET/CT scan could be valuable noninvasive tool for determining stages of ovarian cancer
8. Past Earnings Play Role in Determining SSDI Benefits
9. Determining Valuations in Challenging Times
10. Gender is key factor in determining overall survival of lung cancer patients
11. Determining risk for pancreatic cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Determining Who Will Respond to Brain Tumor Therapy
(Date:5/4/2016)... , ... May 04, 2016 , ... ... Continence Nurses (WOCN) Society™ and Canadian Association for Enterostomal Therapy (CAET) will ... time saving and planning tools to attendees and exhibitors for the 2016 WOCN ...
(Date:5/4/2016)... Charles, LA (PRWEB) , ... May 04, 2016 , ... ... Charles, LA area has teamed up with Big Brothers Big Sisters of Southwest Louisiana ... now being accepted here . , Big Brothers Big Sisters of Southwest Louisiana ...
(Date:5/4/2016)... ... May 04, 2016 , ... Washington Wellness Center today announced its tenth anniversary ... What started out as an idea to provide a holistic approach to wellness ... , Developed by Dr. David Swanekamp, Chiropractic Physician , the wellness center offers ...
(Date:5/4/2016)... , ... May 04, 2016 , ... ... 2016. SS&A teamed up with one of the top website design companies to ... contains informative legal articles related to the law firm's main practice areas. These ...
(Date:5/4/2016)... ... May 04, 2016 , ... Momsense, ... nursing mothers. The company’s patented technology, The Smart Breastfeeding Meter, is designed to ... that the technology is now available for purchase at Target.com . ...
Breaking Medicine News(10 mins):
(Date:5/4/2016)... YORK , May 4, 2016 ... Share, Development, Growth and Demand Forecast to 2022 - Industry ... User (Hospital, Diagnostic Center and Others)" by P&S Market Research, ... $4,894.3 million in 2015, and it is expected to grow ... type, the high slice type segment is expected to witness ...
(Date:5/4/2016)... 4, 2016 In March, ... series of free workshops across Africa ... requirements for Good Distribution Practices (GDP). Good Distribution ... that products are consistently stored, transported and handled under ... or product specification. Only a few years ago, there ...
(Date:5/4/2016)... , May 4, 2016 ... addition of the  "Global Multiple Myeloma Market ... to their offering.       (Logo: ... Myeloma Market and Competitive Landscape Highlights 2016, ... products, Multiple Myeloma epidemiology, Multiple Myeloma market ...
Breaking Medicine Technology: