Navigation Links
Determining Who Will Respond to Brain Tumor Therapy
Date:6/23/2009

Blood biomarker, combined with MRI scan, helps predict outcome, study finds,,

TUESDAY, June 23 (HealthDay News) -- A new biomarker that may help predict whether someone with a brain tumor will respond to a given treatment has been identified by U.S. researchers.

Looking to see who would respond to anti-vascular endothelial growth factor therapy, they used MRIs to scan the brains of people with recurrent glioblastoma, or malignant brain tumors, after they took an experimental drug called cediranib. By measuring vascular normalization, the researchers were able to identify, even after a single dose, people who benefitted from the drug and those who did not.

People with a greater degree of vascular normalization had longer overall survival and longer progression-free survival, according to the phase 2 study, which included 31 people.

"We found that results from an advanced MRI scan taken just a day after starting treatment correlated with survival," Dr. A. Gregory Sorensen, an associate professor of radiology and health sciences and technology at Harvard Medical School and Massachusetts General Hospital, said in a news release. "Combining MRI with blood biomarkers did an even better job of identifying patients who best responded to treatment."

"If this approach is validated in larger studies, we could use these tools to keep patients on therapies that their tumors respond to and shift non-responders to other therapies much earlier," he added.

The study appears in the journal Cancer Research.

More information

The U.S. National Cancer Institute has more about brain tumors.



-- Robert Preidt



SOURCE: American Association for Cancer Research, news release, June 23, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. NEJM Report Finds HPV Test More Effective Than Pap in Determining Cervical Cancer Risk
2. CSHL scientists make progress in determining how the brain selectively interprets sound
3. New method proposed for determining which patients should get treatment for colorectal cancer
4. New Method Proposed for Determining Which Patients Should Get Treatment for Colorectal Cancer
5. Determining genetic signature of lung tumors can help guide treatment
6. Fitness a Key Element in Determining Male Diabetics Longevity
7. PET/CT scan could be valuable noninvasive tool for determining stages of ovarian cancer
8. Past Earnings Play Role in Determining SSDI Benefits
9. Determining Valuations in Challenging Times
10. Gender is key factor in determining overall survival of lung cancer patients
11. Determining risk for pancreatic cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Determining Who Will Respond to Brain Tumor Therapy
(Date:9/17/2014)... 2014 The Delta Dental Community Care ... National Children’s Oral Health Foundation: America’s ToothFairy (NCOHF) to ... County Oral Health Zone Program® in California. , The ... a range of local constituent groups and stakeholders in ... tooth decay and its devastating effects on local families. ...
(Date:9/17/2014)... diabetes, quitting smoking, controlling high blood pressure, exercising and ... dementia -- even late in life, according to new ... by Alzheimer,s Disease International, revealed that diabetes can increase ... noted that obesity and an inactive lifestyle are key ... pressure. The researchers suggested that dementia should ...
(Date:9/17/2014)... not properly designed to meet the needs of patients ... families, and major changes to the system are necessary, ... The 21-member committee that wrote the report envisioned ... care and social services and that is high-quality, affordable, ... care planning" for end-of-life by individuals, for improved training ...
(Date:9/17/2014)... most 18-month-olds learn an average of two to five ... how children process information to learn new words as ... study, a University of Missouri researcher has found that ... limit exists as to how many words they can ... their children,s vocabularies and assist speech-language professionals in developing ...
(Date:9/17/2014)... 17, 2014 CarePoint Health became the ... 150 CarePoint Health employees participated in the Ice Bucket ... Association. The event took place on September 9, ... CarePoint Health donated $100 to the ALS Association for ... total of approximately $15,000. The Ice Bucket Challenge was ...
Breaking Medicine News(10 mins):Health News:Delta Dental Community Care Foundation Donation to America's ToothFairy Helps Deliver Critical Services 2Health News:Healthy Lifestyle Changes Linked to Reduced Risk for Dementia 2Health News:Healthy Lifestyle Changes Linked to Reduced Risk for Dementia 3Health News:US health system not properly designed to meet needs of patients nearing end of life, says IOM 2Health News:US health system not properly designed to meet needs of patients nearing end of life, says IOM 3Health News:US health system not properly designed to meet needs of patients nearing end of life, says IOM 4Health News:US health system not properly designed to meet needs of patients nearing end of life, says IOM 5Health News:Babies learn words differently as they age, researcher finds 2Health News:CarePoint Health Accepts the Ice Bucket Challenge 2Health News:CarePoint Health Accepts the Ice Bucket Challenge 3
... reveals that virgin olive oil is the best among vegetable ... the Annals of Internal Medicine.// It says heart disease risk ... first pressing of olives gives virgin olive oil. Refined oil ... polyphenols than the latter. ,The study was conducted ...
... intelligent ways to conquer the ubiquitous problem of the bulge, ... protein rich diet vis a vis carbohydrate or fat laden ... of fewer calories that wards off obesity. ... the quantity of peptide YY (PYY), a hormone that actually ...
... situation can play an important role in inspiring memory. ... conducting a more in-depth research// on the formation of ... very anticipation of a fearful situation can stir up ... event has occurred. ,The researchers explained that ...
... women patients who wish to preserve their modesty for religious ... in Lancashire have asked a Calderdale firm is to make ... patients for protection of their religious beliefs. ... considered the first of its kind to be introduced in ...
... have a decreased risk of developing diabetes, according to ... The study found that// only 8 percent of the ... percent of those on older drugs. ,The ... Norvasc and Coversyl with a beta-blocker and a diuretic. ...
... the American Medical Association finds that despite the existing ... training, or// residency includes shifts that involve working long ... Medical Education (ACGME) say that they must be allowed ... Medical School, and colleagues said that interns reported working ...
Cached Medicine News:Health News:Anticipation Could Have An Intense Effect On Memory 2Health News:Anticipation Could Have An Intense Effect On Memory 3Health News:Burka Style Inter-faith Gowns For Muslim Patients In UK 2
(Date:9/17/2014)... Women everywhere know how frustrating a vaginal ... they,re often also embarrassing and have a way of ... ( http://ph-defense.com ) is a new, over-the-counter product designed ... product. Odor, discharge, and discomfort or ... In many cases, the cause of such problems can ...
(Date:9/17/2014)... N.J. , Sept. 17, 2014   ... details how to implement GS1 Standards to support ... and enhance patient safety and security in the ... Applying GS1 Standards to U.S. Pharmaceutical Supply Chain ... Security Act , was developed in collaboration ...
(Date:9/17/2014)... MILL VALLEY, Calif. , Sept. 17, ... announced a partnership in the fight against sarcoma. ... Sarcoma Alliance Suzanne Renee Leider Memorial Assistance Fund. ... assistance to reimburse sarcoma patients for expenses directly ... sarcoma specialist. Scientific literature reinforces the importance of ...
Breaking Medicine Technology:New Product from Vireo Systems: pH-D Feminine Health Support 2New Healthcare Industry Guideline Delineates How to Implement GS1 Standards to Support Requirements of the 2013 Drug Supply Chain Security Act 2New Healthcare Industry Guideline Delineates How to Implement GS1 Standards to Support Requirements of the 2013 Drug Supply Chain Security Act 3New Healthcare Industry Guideline Delineates How to Implement GS1 Standards to Support Requirements of the 2013 Drug Supply Chain Security Act 4Champions Oncology Partners with Sarcoma Alliance to Bring Personalized Treatment Options to Sarcoma Patients 2Champions Oncology Partners with Sarcoma Alliance to Bring Personalized Treatment Options to Sarcoma Patients 3
... Inc., the global leader in cold chain visibility ... (IATA) has deemed Sensitech,s full range of temperature ... with the 53rd edition of the IATA Dangerous ... the United Nations.   The size and lithium metal ...
...  Online news publication in-PharmaTechnologist.com ... news in key biopharma manufacturing niches. Using the ... of four microsites - Ingredients , Processing , ... - each of which delivers highly targeted news. ...
Cached Medicine Technology:Sensitech Inc. Products Receive Regulatory Compliance Approval from IATA 2Industry Leading Pharmaceutical News Website in-Pharmatechnologist.com Refocused and Relaunched 2
Two-channel, Berman design. Semirigid, nontoxic polyethylene. Individually packaged, 48 per case. Latex Free....
Black elastomer. Smooth finish. Non-Sterile....
Guedel-style enclosed center channel. Semirigid, nontoxic polyethylene with color-coded bite block. Individually packaged, 48 per case. Latex Free....
Includes one of each size airway. Plastic. Color coded for size. Single use. Non-Sterile....
Medicine Products: