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Detection of breast cancer in screening mammography has improved over time
Date:5/26/2010

OAK BROOK, Ill. (May 26, 2010) Researchers analyzing 2.5 million screening mammograms performed on nearly one million women found discrimination of cancerous from non-cancerous lesions improved over a nine-year period. Results of the study are published in the online edition of the journal Radiology.

"To our knowledge, this is the first study of time trends for performance measures in a large representative sample of women undergoing screening mammography in the United States," said lead author Laura E. Ichikawa, M.S., biostatistician at the Group Health Research Institute in Seattle, Washington.

The research team examined data from six mammography registries in the Breast Cancer Surveillance Consortium. The data included 2,542,049 screening mammograms of 971,364 women (age 40 to 79) performed at healthcare facilities throughout the country between 1996 and 2004.

Each of the women included in the study had at least one prior mammogram and at least nine months in between mammography exams. Cancer registries and pathology databases were used to identify breast cancers that occurred within one year of any mammogram included in the study.

"We found universal trends that breast imagers are increasing their ability to detect and intercept breast cancer before a lump is felt by a woman," said study co-author R. James Brenner, M.D., professor of clinical radiology at the University of California, San Francisco.

Analysis of the radiologists' performance in interpreting the mammograms over the nine-year time period revealed an increase in the recall rate, or mammograms resulting in patients being called back for further evaluation, from 6.7 percent (10,779 of 160,329 mammograms) in 1996 to 8.6 percent (24,630 of 285,286) in 2004.

The sensitivity rate, or the ability of radiologists to identify cancer when present, increased from 71.4 percent in 1996 to 83.8 percent in 2004. The specificity rate, or the deg
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Contact: Maureen Morley
media@rsna.org
630-590-7762
Radiological Society of North America
Source:Eurekalert

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