Navigation Links
Detecting autism from brain activity
Date:4/17/2013

Neuroscientists from Case Western Reserve University School of Medicine and the University of Toronto have developed an efficient and reliable method of analyzing brain activity to detect autism in children. Their findings appear today in the online journal PLOS ONE.

The researchers recorded and analyzed dynamic patterns of brain activity with magnetoencephalography (MEG) to determine the brain's functional connectivity that is, its communication from one region to another. MEG measures magnetic fields generated by electrical currents in neurons of the brain.

Roberto Fernndez Galn, PhD, an assistant professor of neurosciences at Case Western Reserve and an electrophysiologist seasoned in theoretical physics led the research team that detected autism spectrum disorder (ASD) with 94 percent accuracy. The new analytic method offers an efficient, quantitative way of confirming a clinical diagnosis of autism.

"We asked the question, 'Can you distinguish an autistic brain from a non-autistic brain simply by looking at the patterns of neural activity?' and indeed, you can," Galn said. "This discovery opens the door to quantitative tools that complement the existing diagnostic tools for autism based on behavioral tests."

In a study of 19 childrennine with ASD141 sensors tracked the activity of each child's cortex. The sensors recorded how different regions interacted with each other while at rest, and compared the brain's interactions of the control group to those with ASD. Researchers found significantly stronger connections between rear and frontal areas of the brain in the ASD group; there was an asymmetrical flow of information to the frontal region, but not vice versa.

The new insight into the directionality of the connections may help identify anatomical abnormalities in ASD brains. Most current measures of functional connectivity do not indicate the interactions' directionality.

"It is not just who is connected to whom, but rather who is driving whom," Galn said.

Their approach also allows them to measure background noise, or the spontaneous input driving the brain's activity while at rest. A spatial map of these inputs demonstrated there was more complexity and structure in the control group than the ASD group, which had less variety and intricacy. This feature offered better discrimination between the two groups, providing an even stronger measure of criteria than functional connectivity alone, with 94 percent accuracy.

Case Western Reserve's Office of Technology Transfer has filed a provisional patent application for the analysis' algorithm, which investigates the brain's activity at rest. Galn and colleagues hope to collaborate with others in the autism field with emphasis on translational and clinical research.

Galn's collaborators and co-authors of this study are University of Toronto's associate researcher, Luis Garca Domnguez, PhD, and professor Jos Luis Prez Velzquez, PhD.


'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Related medicine news :

1. Dentists Play Key Role in Detecting Oral Cancer
2. Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis
3. Studies See Advances in Detecting, Treating Pancreatic Cancer
4. New technology represents next-generation tool for detecting substandard and counterfeit medicines
5. Detecting thyroid disease by computer
6. Pharmacists provide additional line of defense for detecting knee osteoarthritis
7. New biomarker may help in detecting gliomas, reports Neurosurgery
8. Amyloid imaging shows promise for detecting cardiac amyloidosis
9. Detecting cocaine naturally
10. Handheld device for detecting counterfeit and substandard medicines tested by PQM
11. Detecting circulating tumor cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/20/2017)... ... July 20, 2017 , ... ... headquartered in Houston, is pleased to announce their expansion to the Midwest with ... experience, directors Alysse Hollis and Ronald Bell, and of counsels, John Peck and ...
(Date:7/20/2017)... (PRWEB) , ... July 20, 2017 , ... Team Type ... access to medicine for everyone affected by diabetes, is teaming up with a Microsoft ... global event kicks off on July 24th. , “Team Type 1’s mission overlaps ...
(Date:7/20/2017)... ... ... Girl Up Campaign Director, Melissa Kilby, released the statement ... providing girls access to education in refugee settings. In May, Congressman Steve Chabot (R-OH) ... Education in Vulnerable Settings Act.” Yesterday, companion legislation was introduced in the Senate ...
(Date:7/20/2017)... (PRWEB) , ... July 20, 2017 , ... ... two products that further expand its existing adherence automation lines. The ATP® Mini ... mirror the advanced technology of TCG’s standard products, but at a size and ...
(Date:7/20/2017)... ... July 20, 2017 , ... With nearly ... top travel insurance solution company VisitorsCoverage Inc. has launched TMQuotes, a new cloud-based ... travel insurance products online, under their own brand. The online marketplace bridges the ...
Breaking Medicine News(10 mins):
(Date:7/10/2017)... -- US medical equipment and supply demand is forecast to ... Medical Equipment & Supplies: United States , a ... in demand for medical services – driven in large ... by gains in disposable personal income – will boost ... will also drive sales as providers and patients seek ...
(Date:7/10/2017)... N.C. , July 10, 2017 Locus ... Convertible Note to support the development of CRISPR-Cas3 antimicrobial ... Holdings Limited, a leading Chinese Internet services provider, and ... will advance multiple infectious disease product programs targeting antibiotic ... Founded by Dr. Rodolphe Barrangou ...
(Date:7/5/2017)... , July 5, 2017 Pace Analytical, a company of over ... today that they have acquired ESC Lab Sciences, further solidifying their position as ... United States . ... Steve Vanderboom- President and CEO of Pace Analytical ... ESC Lab Sciences out of Mt Juliet, TN , enhances ...
Breaking Medicine Technology: