Navigation Links
Detecting autism from brain activity
Date:4/17/2013

Neuroscientists from Case Western Reserve University School of Medicine and the University of Toronto have developed an efficient and reliable method of analyzing brain activity to detect autism in children. Their findings appear today in the online journal PLOS ONE.

The researchers recorded and analyzed dynamic patterns of brain activity with magnetoencephalography (MEG) to determine the brain's functional connectivity that is, its communication from one region to another. MEG measures magnetic fields generated by electrical currents in neurons of the brain.

Roberto Fernndez Galn, PhD, an assistant professor of neurosciences at Case Western Reserve and an electrophysiologist seasoned in theoretical physics led the research team that detected autism spectrum disorder (ASD) with 94 percent accuracy. The new analytic method offers an efficient, quantitative way of confirming a clinical diagnosis of autism.

"We asked the question, 'Can you distinguish an autistic brain from a non-autistic brain simply by looking at the patterns of neural activity?' and indeed, you can," Galn said. "This discovery opens the door to quantitative tools that complement the existing diagnostic tools for autism based on behavioral tests."

In a study of 19 childrennine with ASD141 sensors tracked the activity of each child's cortex. The sensors recorded how different regions interacted with each other while at rest, and compared the brain's interactions of the control group to those with ASD. Researchers found significantly stronger connections between rear and frontal areas of the brain in the ASD group; there was an asymmetrical flow of information to the frontal region, but not vice versa.

The new insight into the directionality of the connections may help identify anatomical abnormalities in ASD brains. Most current measures of functional connectivity do not indicate the interactions' directionality.

"It is not just who is connected to whom, but rather who is driving whom," Galn said.

Their approach also allows them to measure background noise, or the spontaneous input driving the brain's activity while at rest. A spatial map of these inputs demonstrated there was more complexity and structure in the control group than the ASD group, which had less variety and intricacy. This feature offered better discrimination between the two groups, providing an even stronger measure of criteria than functional connectivity alone, with 94 percent accuracy.

Case Western Reserve's Office of Technology Transfer has filed a provisional patent application for the analysis' algorithm, which investigates the brain's activity at rest. Galn and colleagues hope to collaborate with others in the autism field with emphasis on translational and clinical research.

Galn's collaborators and co-authors of this study are University of Toronto's associate researcher, Luis Garca Domnguez, PhD, and professor Jos Luis Prez Velzquez, PhD.


'/>"/>

Contact: Jessica Studeny
jessica.studeny@case.edu
216-368-4692
Case Western Reserve University
Source:Eurekalert

Related medicine news :

1. Dentists Play Key Role in Detecting Oral Cancer
2. Detecting malaria early to save lives: New optical technique promises rapid and accurate diagnosis
3. Studies See Advances in Detecting, Treating Pancreatic Cancer
4. New technology represents next-generation tool for detecting substandard and counterfeit medicines
5. Detecting thyroid disease by computer
6. Pharmacists provide additional line of defense for detecting knee osteoarthritis
7. New biomarker may help in detecting gliomas, reports Neurosurgery
8. Amyloid imaging shows promise for detecting cardiac amyloidosis
9. Detecting cocaine naturally
10. Handheld device for detecting counterfeit and substandard medicines tested by PQM
11. Detecting circulating tumor cells
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/21/2017)... ... February 21, 2017 , ... Hanna Boys Center http://www.hannacenter.org ... be the keynote speaker at its second Professional Networking Breakfast on March 9, ... develops comprehensive strategies to create and expand opportunities for boys and young men ...
(Date:2/21/2017)... ... February 21, 2017 , ... ... conditions and problems directly related to surgery, treatment, therapy and management. Regular exercise ... enjoy better qualities of life despite their diseases. On February 23, 2017, 1:00-2:00 ...
(Date:2/21/2017)... ... February 21, 2017 , ... ... coverage in veterinary medicine, will be launching its first bi-monthly issue of 2017 ... medicine, business and practice management, and One Health. , In making the ...
(Date:2/21/2017)... , ... February 21, 2017 , ... ... acquisition of the predictive analytic firm Predixion’s Healthcare IT practice. Predixion, which raised ... and is backed by giants including Accenture, GE Ventures, and Software AG ...
(Date:2/21/2017)... ... February 21, 2017 , ... A February 6 article ... for weight loss. It found that the treatments have led to significant improvements in ... compared to unassisted efforts. It also noted very few problematic results relating to the ...
Breaking Medicine News(10 mins):
(Date:2/21/2017)... 2017 Diabetic Shoes Market: Overview Read ... ... a disease, which is marked by high levels of blood ... The disease has become a global epidemic leading to serious ... organs of the body including eyes, kidneys, heart. However, it ...
(Date:2/21/2017)... 21, 2017 Medical Oxygen Concentrators Market: ... http://www.reportlinker.com/p04711311-summary/view-report.html Medical oxygen concentrators are used ... diseases. Patients having low level of oxygen in ... Oxygen concentrators are to be used only with ... Medical oxygen concentrators work either on rechargeable lithium ...
(Date:2/21/2017)... Feb. 21, 2017  Global health services company Cigna ... ® for breast reconstruction surgery and Dermacell ... an advanced acellular dermal matrix developed by LifeNet Health ... NVDQ ) "We are proud ... health-care payers to review the growing base of evidentiary ...
Breaking Medicine Technology: