Navigation Links
Depression overlooked in patients with hepatitis C; compromising HCV therapy
Date:7/20/2010

Researchers from Denmark, Sweden, Norway and Finland (the NORDynamIC project group) have observed that depressive symptoms in patients with hepatitis C virus (HCV) infection are commonly overlooked in routine clinical interviews, and that treatment-induced depression compromises the outcome of HCV therapy. A second U.S. study found that patients with chronic infection had lower (work) productivity and incurred higher medical benefit costs than those without HCV. Both studies are available in the August issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases (AASLD).

HCV is a blood-born infection causing inflammation and destruction of liver cells. When inflammation lasts longer than six months there is ongoing liver cell injury which is defined as chronic HCV. The standard treatment protocol for chronic HCV is weekly injections of peg-interferon alfa-2a in combination with daily oral ribavirin for 24 to 48 weeks. However, this combination treatment can lead to major depression or other psychiatric complications in a number of HCV patients which may require premature termination of the antiviral therapy.

Peter Leutscher, M.D., Ph.D., and colleagues estimated the value of routine medical interviews in diagnosing depression in chronic HCV patients receiving peg-interferon/ribavirin therapy using the Major Depression Inventory (MDI). The MDI is a self-rating depression scale with a dual functionality in diagnosing major depression and in measurement of depression severity. Of the 325 HCV patients enrolled in the study, 6% were observed with major depression at baseline. Among the remaining 306 patients, 37% (n=114) developed depression while on HCV combination therapy. "According to the MDI criteria, we found that only 32% of the 114 patients with major depression were correctly diagnosed during routine medical interviews," noted Dr. Leutscher.

Rese
'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. Husbands hostile, anti-social behaviors increase wives symptoms of depression, researchers find
3. Acupuncture May Ease Depression During Pregnancy
4. Belief in a caring god improves response to medical treatment for depression
5. Stress hormone, depression trigger obesity in girls
6. Psychiatrys main method to prevent mistaken diagnoses of depression doesnt work: NYU study
7. Brain Balancing Gives Hope for Sufferers of Depression, Stress, and Insomnia at New Life Brain Center
8. Video games may help combat depression in older adults
9. Obesity and Depression: A Vicious Circle?
10. Major depression more than doubles risk of dementia among adults with diabetes
11. Study shows phyical therapy exercise program can reduce risk of postnatal depression in new mothers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/1/2015)... Linda Kincaid, age 67, knew something was wrong. She constantly ... thought it was just a part of getting older, but ... After going to the doctor, she received a distressing diagnosis: ... might happen to her. , Linda is not alone. As ... each year. Valve disease involves damage to one or more ...
(Date:6/1/2015)... Portland, Ore. (PRWEB) June 01, 2015 ... Plans (AHIP) announced today a new, interactive Affordable ... support large employers. The course, called “Affordable Care ... care professionals with the strategic and consultative insights ... employers as they navigate the impacts of the ...
(Date:6/1/2015)... NY (PRWEB) June 01, 2015 For ... patients requesting celebrity features. Much like one would request ... stars’ noses, eyes, cheeks, chin and more to illustrate ... filtering apps like FaceTune are ushering in a new ... Manhattan facial plastic surgeon, Sam Rizk, MD, FACS notes ...
(Date:6/1/2015)... June 01, 2015 Listen to Volvo’s ... automotive companies are using more granular data to create ... comparatively new industry voices in Josep Celaya Gonzalez, CIO ... start-up ParkTAG. As an automotive insurer, MAPFRE are well ... an easy-to-use solution to the driver. Award winning start-up ...
(Date:6/1/2015)... 2015 A University of Texas ... signaling proteins that activate protein degradation, which helps ... 1 , The study published April 3rd ... Spraque-Dawley rats 2-3 months of age who performed ... given either whey protein (.4g/kg), low-dose Sustamine (.1g/kg), ...
Breaking Medicine News(10 mins):Health News:A New Online Resource for Those Living with Heart Valve Disease 2Health News:A New Online Resource for Those Living with Heart Valve Disease 3Health News:Cambia Partners with AHIP to Offer Expert Series ACA Training Course 2Health News:Cambia Partners with AHIP to Offer Expert Series ACA Training Course 3Health News:Instagram Filters Launch New Facial Plastic Surgery Trend 2Health News:Complimentary Webinar: Volvo, MAPFRE and Award Winning Start-Up discuss new Frontier of In-Car Services 2Health News:Study Shows Taking Sustamine® L-Alanyl-L-Glutamine May Reduce Muscle Protein Breakdown After Resistance Exercise 2Health News:Study Shows Taking Sustamine® L-Alanyl-L-Glutamine May Reduce Muscle Protein Breakdown After Resistance Exercise 3
... of poor children with congenital heart diseases (CHD) here moved ... the US by a non-profit organization. About 40-50 NRIs have ... keen to sponsor a child or two every year ... born in India with CHD. Only six to eight percent ...
... devised a new system that ranks foods according to ... and developed// by a panel of independent nutritionists, dietitians, ... as well as members of the government’s Scientific Advisory ... developed by the UK’s Food Standards Agency (FSA) has ...
... change in the genetic constitution is what makes each ... is unraveled, then health care can be individualized according ... same genetic code, how those genes express themselves at ... medicines and dietary advice. According to a recent study, ...
... among couples who smoke according to a new study// which ... stroke than cigarette-smoking women with non-smoking spouses. ,The study ... total stroke and ischemic stroke (a stroke caused by a ... groups of women. The relative risk of total stroke was ...
... fine combing of wet hair may be far more ... ,Researchers have used single blind randomized controlled trial ... counter insecticide treatments against head lice in United Kingdom. ... more effective than current over the counter chemical treatments ...
... with severe asthma according to a recent study.// This ... of antioxidants such as vitamin C and incidence of ... intakes and blood concentrations of antioxidants, including vitamin C, ... without asthma. , ,Men with severe asthma had ...
Cached Medicine News:Health News:Nutrient Profiling System Launched By Food Officials in UK 2Health News:Learning Just How Different We Are 2Health News:Combing Hair More Effective Than OTC Medicine For Head Lice 2
(Date:6/1/2015)... , June 1, 2015   Regulus Therapeutics ... company leading the discovery and development of innovative ... G. Xanthopoulos , Ph.D. has resigned as President ... of Regulus, Board of Directors, effective today, to ... Grint, M.D., who previously served as Chief Medical ...
(Date:6/1/2015)... , June 1, 2015 The nuclear ... by 2020 at a CAGR of 12.08%. Nuclear medicine ... diseases. The two major types of Nuclear imaging used ... was the mainstream modality for nuclear medicine applications like ... to change because of global shortage of molybdenum-99 isotope ...
(Date:6/1/2015)... DURHAM, N.C. , June 1, 2015  bioMérieux, ... vitro diagnostics, has been invited to join the ... of antibiotic use in the U.S. as a means ... various sectors, will gather tomorrow, June 2, 2015, to ... next five years to slow the emergence of antibiotic-resistant ...
Breaking Medicine Technology:Regulus' Kleanthis G. Xanthopoulos, Ph.D., to Step Down as President and Chief Executive Officer 2Regulus' Kleanthis G. Xanthopoulos, Ph.D., to Step Down as President and Chief Executive Officer 3Regulus' Kleanthis G. Xanthopoulos, Ph.D., to Step Down as President and Chief Executive Officer 4North America Nuclear Imaging Market - Growth, Trends And Forecasts (2014 - 2019) 2North America Nuclear Imaging Market - Growth, Trends And Forecasts (2014 - 2019) 3bioMerieux Honored to Participate in the White House Forum on Antibiotic Stewardship 2bioMerieux Honored to Participate in the White House Forum on Antibiotic Stewardship 3
... Sept. 13, 2011 Rare Disease Therapeutics, Inc. (RDT) ... Immune F(ab,)2 (Equine) Injection) is now available on the ... owned subsidiary of Medco Health Solutions, Inc. (NYSE: MHS). ... approved by the United States Food and Drug Administration ...
... CARLSBAD, Calif., Sept. 13, 2011 Isis Pharmaceuticals, Inc. (Nasdaq: ... announced that management will present a company overview at UBS, ... 2011 at 1:30 p.m. ET at the Grand Hyatt New ... will be available on the "Investors & Media" section of ...
Cached Medicine Technology:Rare Disease Therapeutics, Inc. Selects Accredo Health Group to Distribute Anascorp® for the Treatment of Centruroides Scorpion Sting Envenomation 2Rare Disease Therapeutics, Inc. Selects Accredo Health Group to Distribute Anascorp® for the Treatment of Centruroides Scorpion Sting Envenomation 3Rare Disease Therapeutics, Inc. Selects Accredo Health Group to Distribute Anascorp® for the Treatment of Centruroides Scorpion Sting Envenomation 4
Coibri handle. Pierse tips with 6 mm platform. 2.5 mm angled tips. Manufactured in titanium....
Straight shafts with 2.0 mm, 1 x 2 Elschnig style teeth. Serrated handle with polished finish. Handle: Wide....
Straight shafts with 45 degrees, 0.12 mm, 2 x 3 teeth and tying platform. Serrated handle with polished finish....
Straight shafts with 0.1 mm Pierse tips. Flat smooth handle with dull finish....
Medicine Products: