Navigation Links
Depression linked with increased risk of peripheral artery disease
Date:8/9/2012

Depression was linked with an increased risk of peripheral artery disease (PAD) in a study of more than one thousand men and women with heart disease conducted by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

PAD is a circulatory problem in which narrowed arteries reduce blood flow to the limbs usually the legs and feet resulting in pain, reduced mobility and, in extreme cases, gangrene and amputation.

The study was published electronically on July 26, 2012, in the Journal of the American Heart Association.

Marlene Grenon, MD, CM, a vascular surgeon at SFVAMC and an assistant professor of Surgery at UCSF, led the analysis of data from 1,024 participants in the Heart and Soul Study, a prospective study of men and women with coronary artery disease who were followed for an average of approximately seven years.

"We discovered that there was an association between depression and PAD at baseline, and also found that the patients who were depressed at the beginning of the study had a higher likelihood of developing PAD during follow-up at seven years," said Grenon.

"These findings add to the growing body of research showing the importance of depression in both the development and progression of PAD," said senior author Beth Cohen, MD, MAS, a physician at SFVAMC and an assistant professor of medicine at UCSF. "This also emphasizes the need for medical providers to be attentive to the mental health of their patients who have developed, or who are at risk for, PAD."

The authors found that some of the risk for PAD was partly explained by modifiable risk factors such as smoking and reduced physical activity.

"We still don't know which comes first," said Grenon. "Is it that patients with PAD become depressed because their mobility is impaired, or that people who are depressed engage in unhealthy behaviors such as smoking and lack of exercise, and are thus more at risk of developing PAD? Or might it be a vicious cycle, where one leads to the other?"

Further research is needed to tease out cause and effect, she said.

The study authors suggest that whatever the initial cause, lifestyle modifications such as being more physically active, eating better, quitting smoking and managing stress more effectively might reduce the risk for the association, as well as potentially address symptoms of both PAD and depression.

"These lifestyle changes would be considered healthy for anyone, and would also help overall cardiovascular health," said Grenon.

"As providers, we can help patients recognize the connections between mental and physical health," added Cohen. "This may help reduce the stigma of mental health diagnosis and encourage patients to seek treatment for problems such as depression."


'/>"/>
Contact: Jennifer O'Brien
jennifer.obrien@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Related medicine news :

1. Depression, Anxiety Tied to Physical Disabilities in Seniors
2. Researchers Develop Blood Test for Depression
3. Speed and ecstasy associated with depression in teenagers
4. Study: No link between depression, nasal obstruction
5. Use of Ecstasy, Speed by Teens Tied to Later Depression
6. Depression Linked to Higher Odds for Poor Leg Circulation
7. Payment innovation cuts depression time in half
8. Being left out puts youths with special needs at risk for depression
9. One-third of adult Americans with arthritis battle anxiety or depression
10. Hepatitis C drug can cause depression
11. Depression in Mid-Life Linked to Higher Odds for Later Dementia
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Depression linked with increased risk of peripheral artery disease
(Date:6/25/2016)... , ... June 25, 2016 , ... Austin residents seeking ... American College of Mohs Surgery and to Dr. Russell Peckham for medical and surgical ... effective treatment for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... ... athletes and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as ... City area —Johnson is one of the first doctors to perform the treatment. ...
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited ... To Recovery® program to drive cancer patients to and from their cancer treatments. ... highest quality of life and ongoing independence. Getting to and from medical treatments ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... client, The Grove Investment Group (TGIG), has initiated cultivation and processing operations at ... Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of a complete ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... June 23, 2016 Research and Markets ... Issue 52" report to their offering. ... treatment creates a favourable commercial environment for MedImmune to enter. ... base that will serve to drive considerable growth for effective ... serve to cap sales considerably, but development is still in ...
(Date:6/23/2016)... , , , WHEN: ... , , , , LOCATION: , , , Online, with ... , EXPERT PANELISTS:  , , , Frost & Sullivan,s Global Vice ... Senior Industry Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... industry is witnessing an exceptional era. Several new demand spaces, such ...
(Date:6/23/2016)... Colombia , June 23, 2016  Astellas today announced the establishment of Astellas Farma Colombia (AFC), a new ... affiliate in Latin America . ... ... ... ...
Breaking Medicine Technology: