Navigation Links
Depression linked with increased risk of peripheral artery disease
Date:8/9/2012

Depression was linked with an increased risk of peripheral artery disease (PAD) in a study of more than one thousand men and women with heart disease conducted by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

PAD is a circulatory problem in which narrowed arteries reduce blood flow to the limbs usually the legs and feet resulting in pain, reduced mobility and, in extreme cases, gangrene and amputation.

The study was published electronically on July 26, 2012, in the Journal of the American Heart Association.

Marlene Grenon, MD, CM, a vascular surgeon at SFVAMC and an assistant professor of Surgery at UCSF, led the analysis of data from 1,024 participants in the Heart and Soul Study, a prospective study of men and women with coronary artery disease who were followed for an average of approximately seven years.

"We discovered that there was an association between depression and PAD at baseline, and also found that the patients who were depressed at the beginning of the study had a higher likelihood of developing PAD during follow-up at seven years," said Grenon.

"These findings add to the growing body of research showing the importance of depression in both the development and progression of PAD," said senior author Beth Cohen, MD, MAS, a physician at SFVAMC and an assistant professor of medicine at UCSF. "This also emphasizes the need for medical providers to be attentive to the mental health of their patients who have developed, or who are at risk for, PAD."

The authors found that some of the risk for PAD was partly explained by modifiable risk factors such as smoking and reduced physical activity.

"We still don't know which comes first," said Grenon. "Is it that patients with PAD become depressed because their mobility is impaired, or that people who are depressed engage in unhealthy behaviors such as smoking and lack of exercise, and are thus more at risk of developing PAD? Or might it be a vicious cycle, where one leads to the other?"

Further research is needed to tease out cause and effect, she said.

The study authors suggest that whatever the initial cause, lifestyle modifications such as being more physically active, eating better, quitting smoking and managing stress more effectively might reduce the risk for the association, as well as potentially address symptoms of both PAD and depression.

"These lifestyle changes would be considered healthy for anyone, and would also help overall cardiovascular health," said Grenon.

"As providers, we can help patients recognize the connections between mental and physical health," added Cohen. "This may help reduce the stigma of mental health diagnosis and encourage patients to seek treatment for problems such as depression."


'/>"/>
Contact: Jennifer O'Brien
jennifer.obrien@ucsf.edu
415-502-6397
University of California - San Francisco
Source:Eurekalert  

Related medicine news :

1. Depression, Anxiety Tied to Physical Disabilities in Seniors
2. Researchers Develop Blood Test for Depression
3. Speed and ecstasy associated with depression in teenagers
4. Study: No link between depression, nasal obstruction
5. Use of Ecstasy, Speed by Teens Tied to Later Depression
6. Depression Linked to Higher Odds for Poor Leg Circulation
7. Payment innovation cuts depression time in half
8. Being left out puts youths with special needs at risk for depression
9. One-third of adult Americans with arthritis battle anxiety or depression
10. Hepatitis C drug can cause depression
11. Depression in Mid-Life Linked to Higher Odds for Later Dementia
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Depression linked with increased risk of peripheral artery disease
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, ... Elite. The attorneys chosen by their peers for this recognition are considered among the ... Traurig Shareholders received special honors as members of this year’s Legal Elite Hall of ...
(Date:6/24/2016)... ... 2016 , ... Comfort Keepers® of San Diego, CA is excited to announce ... program to drive cancer patients to and from their cancer treatments. Comfort Keepers ... of life and ongoing independence. Getting to and from medical treatments is one ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... People across ... in Genome magazine’s Code Talker Award, an essay contest in which patients and their ... award to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty Network, ... M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... the most handsome men, look naturally attractive. Plastic surgery should be invisible.” He ...
(Date:6/24/2016)... Frederick, Maryland (PRWEB) , ... June 24, 2016 ... ... Mid-Atlantic Angels is actively feeding the Frederick area economy by obtaining investment capital ... support over the past 2½ years that have already resulted in more than ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... startling report released today, National Safety Council research shows ... plan to eliminate prescription opioid overdoses. Prescription Nation ... the worst drug crisis in recorded U.S. history, assigned a "Making ... , New Mexico , Tennessee ... states, three – Michigan , Missouri ...
(Date:6/23/2016)... Research and Markets has announced the addition of ... Forecast to 2022" report to their offering. ... date financial data derived from varied research sources to present ... impact on the market during the next five years, including ... sub markets, regional and country level analysis. The report provides ...
(Date:6/23/2016)... Research and Markets has announced the addition of the ... offering. The current unmet ... for MedImmune to enter. The US ageing population creates a ... considerable growth for effective anti-influenza medications. The introduction of a ... development is still in its infancy. Key ...
Breaking Medicine Technology: