Navigation Links
Depression increases death risk in coronary stent patients
Date:3/16/2012

Copenhagen, 16 March 2012: Depression increases the risk of death in patients who have a coronary stent implanted. After seven years of follow up, depressed patients were 1.5 times more likely to have died than non-depressed patients. The findings were independent of age, gender, clinical characteristics, anxiety and the distressed (Type D) personality.

The research was presented at the 12th Annual Spring Meeting on Cardiovascular Nursing, 16-17 March, in Copenhagen, Denmark.

Depression has been associated with poor outcomes in coronary artery disease but previous studies have mainly looked at short term effects, primarily in patients who have had a myocardial infarction or a coronary bypass operation. The current study (FPN 17) investigated the impact of depression on mortality during a 7-year follow up period in patients treated with percutaneous coronary intervention (PCI).

For the study, 1,234 PCI patients aged 26-90 years (average age 62) from the Rapamycin- Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry completed the Hospital Anxiety and Depression Scale (HADS) to assess depression 6 months after having a stent implanted. The endpoint was all-cause mortality.

The prevalence of depression was 26.3% (324 out of 1234 patients). After 7 years there were 187 deaths in total (15.2%). The incidence of all-cause mortality in depressed patients was 23.5% (76 out of 324 patients) versus 12.2% (111 out of 910 patients) in non-depressed patients.

Depression was independently associated with all-cause mortality (hazard ratio=1.56; 95% confidence interval [1.03𔃀.35], p = .035) after adjusting for sociodemographics (age, gender), clinical characteristics, anxiety and the Type D personality. Clinical characteristics included type of stent (drug eluting/bare metal), number of vessels obstructed, body mass index, past cardiac surgery or myocardial infarction, indication for the PCI procedure, coronary risk factors (hypertension, hypercholesterolemia, diabetes, family history of cardiovascular disease, smoking) and cardiac medications (aspirin, ACE inhibitors, beta blockers, calcium antagonists, diuretics, nitrates and statins).

Male gender, older age, and diabetes mellitus were also significantly associated with an increased risk of death after 7 years of follow up, whereas statins were associated with a reduced risk. Anxiety and Type D personality had no significant effect on all-cause mortality.

"The main finding is that patients who are depressed after coronary stenting have a worse prognosis," says lead author Nikki Damen, a PhD student at Tilburg University in the Netherlands. "They die earlier than non-depressed patients."

The reasons for the finding are under investigation. One possible explanation is that depressed patients may have less healthy lifestyles with regard to smoking, drinking alcohol, physical activity, and diet, and may be less likely to take their medications. Another possible explanation is that depression could alter the activity of the sympathetic nervous system, leading to increases in heart rate and blood pressure.

"Doctors and nurses have traditionally focussed on medical factors like diabetes or family history of cardiovascular disease when assessing PCI patients' risk of death, but that's not the whole picture," says Ms Damen. "Psychological factors do matter as well, in combination with the medical factors."

She adds: "More research is needed to determine how to screen for depression in cardiovascular patients, and then how to provide treatment."


'/>"/>

Contact: ESC Press Office
press@escario.org
33-049-294-8627
European Society of Cardiology
Source:Eurekalert

Related medicine news :

1. Hiding emotions may exacerbate depression among black men who confront racial discrimination
2. More effective treatments urgently needed for adolescent depression
3. Depression Could Worsen Mental Decline in Heart Patients
4. Dads Depression May Rub Off on Childs Behavior
5. Could a Statin Lower Your Risk for Depression?
6. Hyperactivity in brain may explain multiple symptoms of depression
7. Statins linked with lower depression risk in heart patients
8. Could Magic Mushrooms Ease Depression?
9. Treating Diabetes, Depression Together May Make Sense
10. Low vitamin D levels linked to depression, UT Southwestern psychiatrists report
11. Celiac Disease in Women Linked to Depression Risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ... certification process to promote standards of excellence for the field of eating disorders, ... March 22 – 25, 2018 in Orlando, Florida at the Omni Resort at ...
(Date:10/13/2017)... ... October 13, 2017 , ... Apple Rehab Shelton Lakes ... a mock evacuation of the facility as part of a disaster drill on October ... Hose EMS and Shelton City Emergency Manager, as well as the Connecticut Long ...
(Date:10/13/2017)... ... ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many kids ... sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids excited ... all ages; it is a non-competitive, non-timed event, which is all about having fun ...
(Date:10/13/2017)... ... 2017 , ... “The Journey: From the Mountains to the Mission Field”: the ... in the Philippines. “The Journey: From the Mountains to the Mission Field” is the ... She has taught all ages and currently teaches a class of ladies at her ...
(Date:10/12/2017)... ... 2017 , ... Planet Fitness, one of the largest and fastest growing franchisors ... a flagship location in Covington, LA at 401 N. U.S. Highway 190, in January ... Office Depot in the Holiday Square shopping center. Its location allows it to serve ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... and NEW YORK , Sept. 27, 2017 ... mobile health and big data solutions, today announced that its MyDario product ... check your local TV listings for when The Dr. Oz Show airs ... The ... this month. ...
(Date:9/25/2017)... R.I. , Sept. 25, 2017  EpiVax, ... assessment, vaccine design, and immune-engineering today announced the ... on the development of personalized therapeutic cancer vaccines. ... has provided exclusive access to enabling technologies to ... Eng., MBA will lead EpiVax Oncology as Chief ...
(Date:9/22/2017)... Sept. 22, 2017  As the latest Obamacare repeal ... Bill Cassidy (R-LA) and Lindsey Graham ... the medical device industry is in an odd place. ... the 2.3% excise tax on medical device sales passed ... want covered patients, increased visits and hospital customers with ...
Breaking Medicine Technology: