Navigation Links
Depression in young people increases risk of heart disease mortality
Date:11/11/2011

The negative effects of depression in young people on the health of their hearts may be stronger than previously recognized. Depression or a history of suicide attempts in people younger than 40, especially young women, markedly increases their risk for dying from heart disease, results from a nationwide study have revealed.

The results are published in the November 2011 issue of Archives of General Psychiatry.

"This is the first study looking at depression as a risk factor for heart disease specifically in young people," says senior author Viola Vaccarino, MD, PhD, chair of epidemiology at Emory's Rollins School of Public Health. "We're finding that depression is a remarkable risk factor for heart disease in young people. Among women, depression appears to be more important than traditional risk factors such as smoking, hypertension, obesity and diabetes which are not common in young women."

First author is Amit Shah, MD, a cardiology fellow at Emory University School of Medicine. The researchers analyzed data from 7,641 people between the ages of 17 and 39 who participated in the NHANES-III (National Health and Nutrition Examination Survey-III), a nationwide survey conducted by the National Center for Health Statistics between 1988 and 1994. Deaths were tracked through 2006.

Women with depression or a history of attempted suicide had a three times higher risk of dying from cardiovascular disease and a 14 times higher risk of dying from ischemic heart disease (heart attack). The corresponding figures for men were 2.4 times higher risk for cardiovascular disease and 3.5 times higher risk for ischemic heart disease.

Many previous studies of depression and heart disease included older individuals, who generally have a larger burden of heart disease risk factors and associated diseases that may confound the results.

This is the first study to examine a history of suicide attempts along with depression as a marker for future mortality from cardiovascular disease. Also, unlike most previous studies of depression and heart disease, the authors examined major depression, which was assessed with a clinical interview based on accepted diagnostic criteria, instead of using questionnaire scores for depression symptoms. The authors suggest that clinical diagnosis may be "a more robust risk indicator."

Use of antidepressants was not included as a risk factor because less than six percent of those with depression or a history of attempted suicide reported their use, and no cardiovascular-related deaths occurred in that subgroup.

The researchers considered the possibility that depressed people may have more lifestyle-related risk factors such as smoking and poor diet. They found a significant link to heart disease risk coming from depression and suicide attempts, even after correcting statistically for unhealthy behaviors.

"Direct physiological effects of depression may play a greater role than lifestyle factors in this young population," the authors write.

Depression may increase risk of heart disease through physiological mechanisms, such as lower heart rate variability and increased cortisol (a stress-related hormone) and inflammation.

"This is a group that normally should be low risk," Vaccarino says. "Studying these individuals more intensively could be important for understanding how depression affects the heart."


'/>"/>
Contact: Jennifer Johnson
jrjohn9@emory.edu
404-727-5696
Emory University
Source:Eurekalert

Related medicine news :

1. When Dads Have Depression, Kids May Be at Risk, Too
2. MU studies link depression and breast cancer outcomes
3. Obesity and depression independently increase health costs
4. Smoking Pot Might Up Depression Risk in Vulnerable Teens
5. MRI study finds that depression uncouples brains hate circuit
6. More screening needed to identify depression, vision loss after mild stroke
7. Lots of Coffee Might Lower Depression Risk: Study
8. Depression After Cancer Keeps Some From Follow-Up Care
9. Study to test efficacy of prenatal intervention, support on lowering postpartum depression in teens
10. Depression Tied to Higher Risk for Stroke
11. Journaling Might Ease Depression in Testicular Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... ... March 24, 2017 , ... Judy Buchanan, co-owner of Serenity ... MD. Judy says, “I am passionate about sharing Reiki as a holistic, complementary ... and challenging time.” , A Certified Medical Reiki™ Master trained by Raven Keys ...
(Date:3/24/2017)... ... , ... “Vintage and Harvest A Cultivation of Christian Love” is the creation ... North Carolina with his wife, Anna Marie. He and his wife are the proud ... also the author of “Shadow and Substance.” , “Love, the agape kind, is seen ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... In 2016 ... now estimates that there could be four million Zika-related cases in the Americas within ... with numbers of US cases reported per year skyrocketing to an estimated 329,000. Yet, ...
(Date:3/23/2017)... ... March 23, 2017 , ... ... to their communities, 16 more public health departments have been awarded national accreditation ... another 4.5 million people into the expanding network of communities across the nation ...
(Date:3/23/2017)... (PRWEB) , ... March 23, 2017 , ... The IoT ... and WiFi connectivity are making a huge impact on businesses and individual consumers alike. ... estimates the IoT will have a value anywhere from $4 trillion to $11 trillion ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)...  GenomeDx Biosciences today announced that six abstracts featuring ... Cancer Classifier tests will be presented at the 32 ... held March 24 to 28, 2017 in ... Europe,s largest urological event showcasing ... field. The abstract titled "Muscle invasive bladder ...
(Date:3/24/2017)... , March 23, 2017  Provectus Biopharmaceuticals, Inc. ... "Company"), a clinical-stage oncology and dermatology biopharmaceutical company, ... Financing Commitment Term Sheet (the "Definitive Financing") it ... of the Company,s stockholders, who are referred to ... a Form 8-K filed with the Securities and ...
(Date:3/23/2017)... March 23, 2017 Mosaic Life Care, based in St. Joseph, ... process across its network of 58 clinics, located in 22 cities, and its flagship ... innovative ways to improve the delivery of health care to its patients, including the ... ... Mosaic Life Care St. Joseph Medical Center ...
Breaking Medicine Technology: