Navigation Links
Depression in young people increases risk of heart disease mortality
Date:11/11/2011

The negative effects of depression in young people on the health of their hearts may be stronger than previously recognized. Depression or a history of suicide attempts in people younger than 40, especially young women, markedly increases their risk for dying from heart disease, results from a nationwide study have revealed.

The results are published in the November 2011 issue of Archives of General Psychiatry.

"This is the first study looking at depression as a risk factor for heart disease specifically in young people," says senior author Viola Vaccarino, MD, PhD, chair of epidemiology at Emory's Rollins School of Public Health. "We're finding that depression is a remarkable risk factor for heart disease in young people. Among women, depression appears to be more important than traditional risk factors such as smoking, hypertension, obesity and diabetes which are not common in young women."

First author is Amit Shah, MD, a cardiology fellow at Emory University School of Medicine. The researchers analyzed data from 7,641 people between the ages of 17 and 39 who participated in the NHANES-III (National Health and Nutrition Examination Survey-III), a nationwide survey conducted by the National Center for Health Statistics between 1988 and 1994. Deaths were tracked through 2006.

Women with depression or a history of attempted suicide had a three times higher risk of dying from cardiovascular disease and a 14 times higher risk of dying from ischemic heart disease (heart attack). The corresponding figures for men were 2.4 times higher risk for cardiovascular disease and 3.5 times higher risk for ischemic heart disease.

Many previous studies of depression and heart disease included older individuals, who generally have a larger burden of heart disease risk factors and associated diseases that may confound the results.

This is the first study to examine a history of suicide attempts along with depression as a marker for future mortality from cardiovascular disease. Also, unlike most previous studies of depression and heart disease, the authors examined major depression, which was assessed with a clinical interview based on accepted diagnostic criteria, instead of using questionnaire scores for depression symptoms. The authors suggest that clinical diagnosis may be "a more robust risk indicator."

Use of antidepressants was not included as a risk factor because less than six percent of those with depression or a history of attempted suicide reported their use, and no cardiovascular-related deaths occurred in that subgroup.

The researchers considered the possibility that depressed people may have more lifestyle-related risk factors such as smoking and poor diet. They found a significant link to heart disease risk coming from depression and suicide attempts, even after correcting statistically for unhealthy behaviors.

"Direct physiological effects of depression may play a greater role than lifestyle factors in this young population," the authors write.

Depression may increase risk of heart disease through physiological mechanisms, such as lower heart rate variability and increased cortisol (a stress-related hormone) and inflammation.

"This is a group that normally should be low risk," Vaccarino says. "Studying these individuals more intensively could be important for understanding how depression affects the heart."


'/>"/>
Contact: Jennifer Johnson
jrjohn9@emory.edu
404-727-5696
Emory University
Source:Eurekalert

Related medicine news :

1. When Dads Have Depression, Kids May Be at Risk, Too
2. MU studies link depression and breast cancer outcomes
3. Obesity and depression independently increase health costs
4. Smoking Pot Might Up Depression Risk in Vulnerable Teens
5. MRI study finds that depression uncouples brains hate circuit
6. More screening needed to identify depression, vision loss after mild stroke
7. Lots of Coffee Might Lower Depression Risk: Study
8. Depression After Cancer Keeps Some From Follow-Up Care
9. Study to test efficacy of prenatal intervention, support on lowering postpartum depression in teens
10. Depression Tied to Higher Risk for Stroke
11. Journaling Might Ease Depression in Testicular Cancer Patients
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2017)... ... ... lyric music video in Final Cut Pro X with ProLyric from Pixel Film Studios. Users ... to any song. ProLyric flies in the text for each section and it hovers around ... for optimal control. ProLyric makes editing any music video or text-based production easier than ever. ...
(Date:6/25/2017)... ... ... CareSet Labs released the Root NPI Graph today at the 2017 ... version of the Doctor Referral teaming dataset commonly available from Medicare. , Originally created ... the “Doctor Referral Dataset” as released by Medicare and “DocGraph” as released by Trotter, ...
(Date:6/24/2017)... Tampa, Fla. (PRWEB) , ... June 24, 2017 ... ... Fla., is now offering genetic testing for medications in select Florida and Texas ... of pharmacogenomics. , This new application of genetic testing recognizes the role ...
(Date:6/24/2017)... ... 24, 2017 , ... The weather is heating up and the days are ... should be aware that the summer months provide more than warmer temperatures that are ... can be negatively affected from direct exposure to the sun. When it comes to ...
(Date:6/23/2017)... ... June 23, 2017 , ... "The ... will ultimately do significant harm to people with all chronic conditions, including mental ... it leaves in place the Affordable Care Act (ACA) requirement that insurers cover ...
Breaking Medicine News(10 mins):
(Date:6/8/2017)... , June 8, 2017   Responding to Heath ... and the death of singer Chris Cornell in ... Rights International offers a free online psychiatric ... consumers and families about psychotropic drug risks. ... who died from an accidental overdose, has called for tighter ...
(Date:6/7/2017)... Iowa , June 6, 2017  Diplomat Specialty Infusion Group, ... sterile compounding environment to its Iowa location. ... Urbandale now features an ISO 7 cleanroom—the standard ... controlled environment with a low level of pollutants. ... more IV nutrition consumers and better serve our Iowa ...
(Date:6/2/2017)... June 2, 2017  NxStage Medical, Inc. (Nasdaq:  NXTM), a leading ... announced new findings demonstrating positive biochemical outcomes related to ... One™. The data will be presented at the ERA-EDTA ... Madrid, Spain . The research ... Dialysis Network in Europe ...
Breaking Medicine Technology: