Navigation Links
Depression in pregnant mothers may alter the pattern of brain development in their babies
Date:12/4/2013

Philadelphia, PA, December 4, 2013 Depression is a serious mental illness that has many negative consequences for sufferers. But depression among pregnant women may also have an impact on their developing babies.

Children of depressed parents are at an increased risk of developing depression themselves, a combination of both genetic and environmental factors. These children also display alterations in the amygdala, a brain structure important for the regulation of emotion and stress. However, prior work in this area has assessed children years after birth, which means that the timing of these alterations has remained unidentified.

Researchers led by Dr. Anqi Qiu at the National University of Singapore now have the answers, with their new work published in the current issue of Biological Psychiatry.

They set out to perform a direct analysis of prenatal maternal depression and variation in the fetal development of the amygdala. To do so, they recruited 157 pregnant women who completed a depression questionnaire during their 26th week of pregnancy. Later, within two weeks of birth, newborns underwent magnetic resonance imaging scans to ascertain the structure of their amygdala and diffusion tensor imaging scans to determine the integrity of the amygdala's pattern of neural connections.

The volume of the amygdala did not differ between the infants regardless of their mothers' depression status. However, the researchers found significantly reduced structural connectivity (i.e., lower fractional anisotropy and lower axial diffusivity) in the right amygdala of infants of mothers with high levels of depression symptoms. In other words, the amygdala's microstructure (e.g., its "wiring") was abnormal in the infants born to depressed mothers.

This important finding suggests that a propensity for abnormal amygdala function, a feature of mood and anxiety disorders, may be transmitted from mother to child during fetal life. This finding suggests one new path that a history of maternal depression might contribute to a life-long increase in the vulnerability to mental illness.

This study provides added evidence supporting the notion that mental health screening should be included among the medical evaluations that women undergo when they discover that they are pregnant. Indeed, the authors conclude that their study supports that "interventions targeting maternal depression should begin early in pregnancy."

"Attention to maternal health during pregnancy is an extremely high priority for society for many reasons," added Dr. John Krystal, Editor of Biological Psychiatry. "The notion that maternal depression might influence the brain development of their babies is very concerning. The good news is that this risk might be reduced by systematic screening of pregnant women for depression and initiating effective treatment."


'/>"/>

Contact: Rhiannon Bugno
Biol.Psych@utsouthwestern.edu
214-648-0880
Elsevier
Source:Eurekalert

Related medicine news :

1. Vitamin D decreases pain in women with type 2 diabetes and depression
2. Upcoming Praeclarus Press Webinar Teaches How to Create a Comprehensive Safety Net for All Mothers Experiencing, or at Risk of Experiencing, Postpartum Depression
3. Birmingham Maple Clinic Interviewed on Bloomfield Bottom Line Regarding Clinical Depression
4. Endorphins Mind & Body Presents Programs to Fight Depression
5. Depression in pregnancy: New study shows preferences for therapy over medication
6. Are probiotics a promising treatment strategy for depression?
7. Studies pinpoint specific brain areas and mechanisms associated with depression and anxiety
8. Diet Doc Hormone Diets & Weight Loss Plans Announce New Hormone Diets to Help New Mothers Lose Weight and Avoid Post Pregnancy Depression
9. Experts Examine the Success of Cognitive Behavioral Therapy in Treating Depression Among Older Veterans
10. Study looks at safety, effectiveness of generics for treating depression
11. Long-term use of prescription-based painkillers increases the risk of depression, SLU researcher finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/10/2016)... ... December 10, 2016 , ... When faced with having to use a toilet ... seat to her body, and contamination of children when they use public toilets. This ... problem that many people face. , The patent-pending SANI-POCKET enables a person to use ...
(Date:12/9/2016)... ... December 09, 2016 , ... Flottman Company is ... As a means of expanding capabilities Flottman has added a G&K Vijuk ... code professional inserts (PIs) and patient package inserts (PPIs) that will marry with ...
(Date:12/9/2016)... ... December 09, 2016 , ... An inventor from Cana, Va., wanted to ... types of amusement park rides. , The patent-pending SAFETY STRAP FOR AMPUTEES improves accessibility. ... and could be set up in a matter of minutes, or even seconds. The ...
(Date:12/9/2016)... ... December 09, 2016 , ... "I had a terrible time trying to ... "I thought that if the nebulizer had a more child-friendly design, then children would ... He developed the patent-pending NEBY to avoid the need to deliver medication via a ...
(Date:12/8/2016)... ... 08, 2016 , ... After enjoying record-breaking attendance at its ... its 33rd Annual Issues & Research Conference, March 2-3, 2017, at the ... conference is “Persistent Challenges and New Opportunities: Using Research to Accelerate the Dialogue." ...
Breaking Medicine News(10 mins):
(Date:12/9/2016)... Research and Markets has announced the addition ... their offering. ... The global travel vaccines market to grow at a CAGR of ... present scenario and the growth prospects of the global travel vaccines ... the revenue generated from the sales of various vaccines administered to ...
(Date:12/8/2016)... Dec. 8, 2016 Australia Ophthalmic Lasers Market ... "Australia Ophthalmic Lasers Market Outlook to 2022", provides key ... report provides value, in millions of US dollars, volume ... - Excimer Lasers, Femtosecond Lasers and YAG Lasers. ... data for each of these market segements, and global ...
(Date:12/8/2016)... 8, 2016 KEY FINDINGS The ... in 2017-2023. Various reasons for growth of the medical ... incidences of chronic diseases, high recovery cost of injuries ... Medical lifting sling refers to an assistive device ... These slings connect to the lift and hold the ...
Breaking Medicine Technology: