Navigation Links
Depression drug may relieve pain from breast cancer treatment, U-M study finds
Date:12/11/2010

ANN ARBOR, Mich. A drug commonly used to treat depression and anxiety disorder was effective at reducing joint and muscle pain associated with a breast cancer treatment, according to a study from the University of Michigan Comprehensive Cancer Center.

The women in the study were taking aromatase inhibitors, a type of drug designed to block the production of estrogen, which fuels some breast cancers. About half of women taking these drugs experience aches and pains in their joints and muscles that cannot be adequately relieved by over-the-counter painkillers. Up to 20 percent of these women will stop taking an aromatase inhibitor because of this pain.

"Since women typically take these drugs for five years, it is important that the side effects not interfere too much with their quality of life, or they will be less likely to continue taking the medicine, which may lead to a greater chance of their breast cancer returning," says study author N. Lynn Henry, M.D., Ph.D., assistant professor of internal medicine at the U-M Medical School.

Henry will present the initial results of the study Dec. 11 at the 33rd Annual San Antonio Breast Cancer Symposium.

The study looked at the drug duloxetine, or Cymbalta, which is used to treat depression and generalized anxiety disorder. It's also been shown to work in multiple other chronic pain conditions, such as fibromyalgia and, more recently, osteoarthritis. It is believed to decrease pain through its actions in the central nervous system.

Of 29 patients evaluated, nearly three-quarters reported that their pain had decreased by at least 30 percent. On average, after eight weeks of treatment, pain scores declined 61 percent. Only one in five patients stopped taking duloxetine because of side effects.

"Duloxetine appears to be effective at reducing the muscle and joint pain many women experience from aromatase inhibitors, with only mild additional side effects," Henry sa
'/>"/>

Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Despite Treatment, Employees with Depression Generate Higher Absentee Costs, According to Thomson Reuters Study
2. Husbands hostile, anti-social behaviors increase wives symptoms of depression, researchers find
3. Acupuncture May Ease Depression During Pregnancy
4. Belief in a caring god improves response to medical treatment for depression
5. Stress hormone, depression trigger obesity in girls
6. Psychiatrys main method to prevent mistaken diagnoses of depression doesnt work: NYU study
7. Brain Balancing Gives Hope for Sufferers of Depression, Stress, and Insomnia at New Life Brain Center
8. Video games may help combat depression in older adults
9. Obesity and Depression: A Vicious Circle?
10. Major depression more than doubles risk of dementia among adults with diabetes
11. Study shows phyical therapy exercise program can reduce risk of postnatal depression in new mothers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... made possible by a test developed at University of ... School of Pharmacy), AURORA, Colo (July 28, 2014) An ... Antiviral Pharmacology Laboratory at the CU School of Pharmacy, ... called Truvada (a combination of tenofovir/emtricitabine), which is taken ... study presented during the AIDS 2014 Conference and published ...
(Date:7/28/2014)... University School of Medicine (BUSM) report variants in a ... developing Alzheimer,s disease (AD). The discovery of this novel ... that target PLXNA4 specifically. These findings appear in the ... most frequent age-related dementia affecting 5.4 million Americans including ... more than 40 percent of people age 85 and ...
(Date:7/28/2014)... Recent research has shown the cumulative impact of ... lead to a range of health problems including obesity, ... desk, or an adjustable sit-to-stand desk, commonly leads to ... to a seated position. , The new Standing ... leg pain and fatigue while working upright. These durable ...
(Date:7/28/2014)... July 28, 2014 The Oneida Indian ... an incredible field of accompanying PGA TOUR players will ... golf analyst Notah Begay III for the seventh annual ... Turning Stone Resort Casino ’s Atunyote® Golf Club on ... include Woods, Jason Dufner, Jimmy Walker, Jonas Blixt, Angel ...
(Date:7/28/2014)... A young couple from a small ... in the media today about parents accidentally leaving children ... of minutes in a hot car. July 31 is ... Emergency Medical Services at NHTSA. , Shaun and Kimberly ... that it’s all too easy to get distracted, the ...
Breaking Medicine News(10 mins):Health News:HIV research findings made possible by a test developed at CU School of Pharmacy 2Health News:Researchers identify potential biomarker for AD 2Health News:New Standing Desk Anti-fatigue Mats from Martinson-Nicholls Reduce Leg Fatigue and Discomfort Working at Standing and Sit-to-Stand Desks 2Health News:Turning Stone Announces that Tiger Woods and Fellow Golfing Elites Will Play at the Seventh Annual Notah Begay III Foundation Challenge 2Health News:Turning Stone Announces that Tiger Woods and Fellow Golfing Elites Will Play at the Seventh Annual Notah Begay III Foundation Challenge 3Health News:Turning Stone Announces that Tiger Woods and Fellow Golfing Elites Will Play at the Seventh Annual Notah Begay III Foundation Challenge 4Health News:Turning Stone Announces that Tiger Woods and Fellow Golfing Elites Will Play at the Seventh Annual Notah Begay III Foundation Challenge 5Health News:'Precious Cargo' App Released to Help Save Babies from the Dangers of Being Accidentally Left Behind in Hot Cars 2
... the rising numbers of “middle age pregnancy” cases are as big ... than one in five babies are born to mothers over the ... NHS resources. This is according to a report by Dr Susan ... said that ministers had to agree that the number of middle ...
... The Central Science Laboratory (CSL) of Britain, Monday questioned India's ... several soft drink brands of Coca Cola and said they ... science director of CSL, said: "We detected no residues of ... question the CSE conclusion as there is no proof of ...
... study found that the use of Herceptin in advanced breast ... − nearly 28 percent of patients treated with Herceptin// ... is that much of the damage to the heart can ... online August 14 in the Journal of Clinical Oncology, concludes ...
... to be a good alternative for identifying risks for kidney ... study conducted by a researcher at the San Francisco VA ... test that is incapable of picking up chronic health risks ... people or others at risk for kidney disease, this is ...
... yellow plant pigments play a role in protecting people ... conducted by the scientists at the University of Wisconsin, ... states that carrots might not actually help a person ... vegetables do have the ability to enhance sight. Researchers ...
... material ,called targeting RNA, to enter cancer cells, and ... expression of a protein that keeps the cells ,alive, ... ,The drug, developed at Duke University Medical ... tests in mice with prostate cancer, the drug ,shrank ...
Cached Medicine News:Health News:British Laboratory Certifies Coke as 'Safe' 2Health News:Herceptin Use May Enhance Cardiac Toxicity, Study 2Health News:Herceptin Use May Enhance Cardiac Toxicity, Study 3Health News:Cystatin C Test- A Reliable Test to Detect Chronic Health Risks 2Health News:Cystatin C Test- A Reliable Test to Detect Chronic Health Risks 3Health News:Yellow Fruits And Vegetables Help In Fight Against Loss Of Eyesight 2
(Date:7/28/2014)... , July 28, 2014  A prospective ... Sweden has validated the performance ... platforms and has associated volumetrically assessed breast density ... Cancer Epidemiology, Biomarkers & Prevention (DOI: 10.1158/1055-9965.EPI-13-1219), ... a tool for widespread breast cancer risk assessment," ...
(Date:7/28/2014)... , July 28, 2014  TNI BioTech, ... biopharmaceutical company focused on the development, marketing and ... has filed definitive proxy materials with the Securities ... Annual Meeting of Shareholders to be held on ... Standard Time. The record date for determining those ...
(Date:7/28/2014)...  ResMed (NYSE: RMD ), an innovator ... sleep-disordered breathing and other chronic respiratory conditions, has won ... against Taiwanese medical device manufacturer APEX Medical Corp. (APEX), ... 210 and 220 masks.  The judgment was entered by ... , is appealable, and applies throughout Germany.  ...
Breaking Medicine Technology:Karolinska Study Published in Cancer Epidemiology, Biomarkers & Prevention Validates Strong Agreement for VolparaDensity across Mammography Systems from Multiple Manufacturers 2Karolinska Study Published in Cancer Epidemiology, Biomarkers & Prevention Validates Strong Agreement for VolparaDensity across Mammography Systems from Multiple Manufacturers 3Karolinska Study Published in Cancer Epidemiology, Biomarkers & Prevention Validates Strong Agreement for VolparaDensity across Mammography Systems from Multiple Manufacturers 4TNI BioTech, Inc., Files Definitive Proxy Materials; Mails Letter Urging Shareholders to Vote the Proxy Card 2TNI BioTech, Inc., Files Definitive Proxy Materials; Mails Letter Urging Shareholders to Vote the Proxy Card 3ResMed Receives Permanent Injunction against APEX in Germany, Continues Enforcement of Patents in Europe 2
...  Althea Technologies, Inc., a leading provider of development ... the appointment of Dr. Kristin DeFife as Director, ... and Marketing. (Logo:  http://photos.prnewswire.com/prnh/20020925/LAW010LOGO ... will be responsible for leading Althea,s microbial biologics ...
... May 1, 2012  Intrepid Investment Bankers LLC ("Intrepid"), ... announced the sale of Newport Medical Instruments, Inc. ... closed on May 1, 2012.  Intrepid acted as ... with the transaction.  (Logo:  ...
Cached Medicine Technology:Althea Technologies Appoints Dr. Kristin DeFife, Director, Biologics Manufacturing And Jack Wright, VP, Sales and Marketing 2Althea Technologies Appoints Dr. Kristin DeFife, Director, Biologics Manufacturing And Jack Wright, VP, Sales and Marketing 3Intrepid Investment Bankers LLC Advises Newport Medical Instruments, Inc. in its Sale to Covidien plc 2
... powerful, lightweight, easy to ... durable foam silicone rubber ... by machine washable cotton ... easily adjusts to all ...
Xenon surgical headlight system is durable, comfortable, lightweight and deliver dependable bright light through a patented shielded fiber optic bundle. It is easy to wear....
View Mex-3 is designed for out-patient surgery, hospital rounds and house calls....
Headlight module is mounted on UltraLite Plus sweatband....
Medicine Products: