Navigation Links
Depression diversity: Brain studies reveal big differences among individuals
Date:5/8/2008

in levels in the brain are linked to depression, but the importance of 5HT1a receptor concentrations in the brains of depressed people has been cloudy. Thats why Zubietas team chose to scan only people who had not yet received antidepressant medications, since some such medications may actually encourage the brains cells to make more serotonin receptors - and masking the actual level of receptors that the person has naturally.

In the study, 5HT1a receptor concentrations were markedly lower in depressed people compared with non-depressed people, in both the left and right hippocampus region of the brain.

But even among depressed people, the lower a persons the 5HT1 receptor levels were, the worse he or she scored on assessments of their ability to function day-to-day - and they less likely he or she was to get relief from symptoms when the researchers prescribed them a common antidepressant.

This finding of individual variation may help explain why in current depression treatment, some patients find great relief from a medication that doesnt help other equally depressed patients, says Zubieta, who is the Phil F. Jenkins Research Professor of Depression in the U-M Department of Psychiatry. He also holds positions in the U-M Nuclear Medicine division, and the Molecular & Behavioral Neuroscience Institute.

The other group of depressed volunteers - both depressed and non-depressed -- received PET scans with a tracer that allowed the researchers to see the mu-opioid receptors in their brains. These receptors are the gateway for signals sent by chemicals called endogenous opioids -- the brains natural painkillers - which are involved in stress response including response to pain.

Another name for the neurotransmitters that bind to mu-opioid receptors is endorphins, which have become known as a feel good chemical involved in reinforcing rewarding experiences. Illicit drugs such as heroin also act upon mu-opioid receptors, crea
'/>"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Several Therapies Show Promise for Vascular Depression
2. Antidepressants do work in depression while evidence for CBT is poorer say experts
3. 2008 Welcome Back Awards Winners Honored for Extraordinary Achievements in the Field of Depression
4. WellPoint Foundation Supports National Campaign Focused on Depression Among Men
5. NAMI: Women and Depression; 1 in 8 in Their Lifetime; Twice the Rate of Men
6. Smokers have a 41 percent higher risk of suffering depression
7. Social form of bullying linked to depression, anxiety in adults
8. HAP Offers Web-Based Support for Depression and Bipolar Disorder
9. Study finds 1 in 5 Iraq and Afghanistan veterans suffer from PTSD or major depression
10. Researchers find disparities in depression among older Hispanics in US
11. Personality study shows risk of first depression episode late in life
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... , ... August 28, 2015 ... ... Inc.’s (AIS) Medicare-Medicaid Dual Eligibles Database have added comprehensive information on two ... demonstration approved for a December 2015 launch; and Idaho’s partnership to revamp ...
(Date:8/28/2015)... , ... August 28, 2015 , ... ... organization, is pleased to welcome TJS Insurance Group as its newest Partner Firm. ... clients guides them and keeps them focused on their goals. Within the past ...
(Date:8/28/2015)... ... August 28, 2015 , ... Popular review ... millionaire dating sites . According to the listings, MillionaireMatch.com bags ... this category. , A spokesperson of Top5MillionaireDatingSites.com said, “This website has ...
(Date:8/28/2015)... Calgary, AB (PRWEB) , ... August 28, 2015 , ... ... disease. The Heart Fit Clinic is now selling External Counterpulsation (EECP or ECP) machines ... The Heart Fit Clinic has been in business since 2007 helping people prevent and ...
(Date:8/28/2015)... ... August 28, 2015 , ... The Plaintiffs Steering Committee ... 2545, Testosterone Replacement Therapy Products Liability Litigation, are in the midst of ongoing ... the PSC may receive for corporate employees involved in the production or marketing ...
Breaking Medicine News(10 mins):Health News:AIS Duals Database: August Update Finds Two New Duals Programs in Rhode Island and Idaho 2Health News:TJS Insurance Group Is Latest Partner Firm To Join United Benefit Advisors 2Health News:TJS Insurance Group Is Latest Partner Firm To Join United Benefit Advisors 3Health News:Top5MillionaireDatingSites.com Publishes Its First List of Reviews of the Best Millionaire Dating Sites 2Health News:Buy New External Counterpulsation (EECP or ECP) With Heart Fit Clinic 2Health News:National Testosterone Lawyers Provide Testosterone Lawsuit MDL Update 2Health News:National Testosterone Lawyers Provide Testosterone Lawsuit MDL Update 3Health News:National Testosterone Lawyers Provide Testosterone Lawsuit MDL Update 4
... ... renowned author, clinician and educator announces the signing of a joint marketing agreement with ... , ... June 18, 2010 -- The Dawson Academy ( www.thedawsonacademy.com ), founded by ...
... ... used as a barometer for hiring this fall, we are about to see a significant pickup ... (PRWEB) June ... to be a leading indicator for future hiring activity. “It only makes sense, says RD Whitney, ...
... ... a sponsor of the annual fundraising MS Luncheons held in Wisconsin which help support families ... Quincy Bioscience recently launched MS HOPE Trials which will investigate how its patented calcium-binding technology ... ...
... ... Present the Life Ball 2010 Fashion Show , ... (PRWEB) June 17, 2010 -- Life Ball 2010 will be held in ... Vienna City Hall Square, as well as thousands of people around the world. The fashion ...
... death rates in sub-Saharan Africa has led to a burgeoning ... elderly, or older adults living alone without the benefit of ... The researchers used existing data to develop the first ... any adult support, as a result of the AIDS epidemic, ...
... to thyroid experts , THURSDAY, June 17 (HealthDay News) ... worry that some may obtain too little iodine. , ... in the U.S. and worldwide. Iodine, essential for the ... several members of the American Thyroid Association wrote in ...
Cached Medicine News:Health News:The Dawson Academy Announces the Signing of a Joint Marketing Agreement with Ads Next™ 2Health News:The Dawson Academy Announces the Signing of a Joint Marketing Agreement with Ads Next™ 3Health News:Onrec Predicts Significant Recruiting Activity this Fall 2Health News:Onrec Predicts Significant Recruiting Activity this Fall 3Health News:Onrec Predicts Significant Recruiting Activity this Fall 4Health News:Quincy Bioscience Sponsors Multiple Sclerosis (MS) Scholarship Program 2Health News:Life Ball: Designers Joining Together in the Fight Against AIDS 2Health News:Life Ball: Designers Joining Together in the Fight Against AIDS 3Health News:Life Ball: Designers Joining Together in the Fight Against AIDS 4Health News:Life Ball: Designers Joining Together in the Fight Against AIDS 5Health News:Orphaned elderly serious casualty of African AIDS epidemic, Stanford study finds 2Health News:Orphaned elderly serious casualty of African AIDS epidemic, Stanford study finds 3Health News:Iodine Levels a Worry as Salt Use Declines 2
(Date:8/27/2015)... 2015 According to a new market research ... Universal, Standing, Bariatric ), Material (Nylon, Padded, Canvas), Usage Type (Disposable, ... by MarketsandMarkets, the Medical Lifting Sling Market is poised to reach ... at a CAGR of 11.4 % from 2015 to 2020. ... rket data T ables and 65 ...
(Date:8/27/2015)...  Now that Intuitive Surgical, Inc.® has announced that ... hospitals with robotic surgery programs need to think about ... where they stand with robotic surgery. Are they performing ... adopted best practices for safety? Should they plan to ... ECRI Institute, which has nearly 50 years, experience ...
(Date:8/27/2015)... Ala. , Aug. 27, 2015 /PRNewswire/ ... Outpatient Pharmacy Provider (IOPP™) is expanding its ... of a medication-focused transition of care program ... named "RxCare Management," provides hospitals with technology ... hospital performance measures that have been mandated ...
Breaking Medicine Technology:Medical Lifting Sling Market Worth USD 706.0 Million by 2020 2Medical Lifting Sling Market Worth USD 706.0 Million by 2020 3Medical Lifting Sling Market Worth USD 706.0 Million by 2020 4ECRI Institute's New Robotic Surgery Service Helps Hospitals Brace for Change 2ECRI Institute's New Robotic Surgery Service Helps Hospitals Brace for Change 3Rx Care Management by Proxsys Rx - Transition of Care Technology Helps Prevent Hospital Medication Errors 2
... June 9, 2011 /PRNewswire-Asia-FirstCall/ -- China Botanic Pharmaceutical Inc. ... "Company"), a developer, manufacturer and distributor of botanical products, ... it will host a conference call at 9:00 a.m. ... financial results for the second quarter of fiscal year ...
... 9, 2011 Reportlinker.com announces that a new ... South and Central America Dental ... http://www.reportlinker.com/p0548448/South-and-Central-America-Dental-Devices-Market-Outlook-to-2017.html?utm_source=prnewswire&utm_medium=pr&utm_campaign=Dental_Equipment South and Central ... Summary GlobalData,s new ...
Cached Medicine Technology:China Botanic Schedules Conference Call to Discuss FY 2011 Second Quarter Results 2Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 2Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 3Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 4Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 5Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 6Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 7Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 8Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 9Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 10Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 11Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 12Reportlinker Adds South and Central America Dental Devices Market Outlook to 2017 13
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: