Navigation Links
Depression common among children with temporal lobe epilepsy
Date:5/23/2013

A new study determined that children and adolescents with seizures involving the temporal lobe are likely to have clinically significant behavioral problems and psychiatric illness, especially depression. Findings published in Epilepsia, a journal published by Wiley on behalf of the International League Against Epilepsy (ILAE), highlight the importance of routine psychiatric evaluation for pediatric epilepsy patientsparticularly for those who do not respond to anti-seizure medications and require epilepsy surgery.

Current medical evidence indicates that mental illness occurs in up to 40% of pediatric epilepsy patients, with depression, anxiety, attention issues and learning difficulties being the most common psychiatric conditions in children. Furthermore, a 2009 study of adult surgical patients found that depression was associated with seizures in the temporal lobea common focus for surgically treated epilepsy according to Sanchez-Gistau et al.1 However, such evidence is not well established in pediatric patients and is the focus of the present study.

"Our research examined whether psychiatric illness was more prominent in children who were unresponsive to anti-seizure medications and had seizures in the temporal lobe versus elsewhere in the brain," explains lead study author, Dr. Jay Salpekar with Children's National Medical Center in Washington, D.C. "In children who do not respond to drug therapy, epilepsy surgery may be the only option to improve their quality of life. Understanding the pediatric patients' mental health status is important, as the severity of psychiatric illness may impact the overall risk-benefit of epilepsy surgery."

For the current study, researchers reviewed case records for 40 children between the ages of 6 and 17, who did not respond to anti-seizure medications. Patients were given pre-surgical psychiatric evaluations and their parents completed the Child Behavioral Checklist (CBCL). The seizure location and suitability for surgical procedures were confirmed by epilepsy specialists.

The investigators found that this pediatric patient group had psychiatric and behavioral problems well beyond what is typically reported in children with chronic epilepsy. Nearly 80% of participants had significant psychiatric symptomsfar greater than the 20%-40% prevalence of mental illness generally found in chronic pediatric epilepsy. Furthermore, children with seizures suspected to be localized in the temporal lobe were more likely to have depression symptoms and more significant behavioral issues reported by parents compared to children with seizures in other brain regions.

Dr. Salpekar concludes, "Given that psychiatric illness, particularly depression, is so prominent in those with temporal lobe seizures, routine psychiatric evaluation appears to be important not only for adults, but also for children and adolescents prior to epilepsy surgery. In fact, it may be beneficial for most patients with medically refractory epilepsy to have a psychiatric assessment, regardless of seizure localization, to improve quality of life." Future studies are needed to investigate the variables associated with mental illness outcomes in patients following epilepsy surgery.


'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Related medicine news :

1. Having Both Migraines, Depression May Mean Smaller Brain
2. Good marriage can buffer effects of dads depression on young children
3. Parent and teacher support protects teens from sleep problems and depression
4. Genes May Boost Womans Risk of Postpartum Depression
5. Depression May Raise Low Blood Sugar Risk in Diabetics
6. Depression May Boost Stroke Risk in Middle-Aged Women, Too
7. Anti-Gay Bullying Tied to Teen Depression, Suicide
8. hCGTreatments / Diet Doc hCG Diets & Weight Loss Plans Announces New Weight Loss Tips to Break the Brutal Cycle of Weight Gain and Depression
9. Circadian clock gene rhythms in brain altered in depression, UC Irvine Health study finds
10. Exercise for patients with major depression -- What kind, how intense, how often?
11. Parental addictions linked to adult childrens depression
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... ... Randall, PharmD ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate ... primary prevention of cardiovascular diseases during the 15th Annual Women’s Health Conference. ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading ... to advocate for action towards gender equality at their inaugural Summit in New York ... globe, and reached a social audience of over 3 million. To watch the Mobilize ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the Mountains to the ... save lost souls in the Philippines. “The Journey: From the Mountains to the Mission ... of the Bible. She has taught all ages and currently teaches a class of ...
(Date:10/12/2017)... ... October 12, 2017 , ... The company has developed ... consumer and regulatory authorities worldwide. From Children’s to Adults 50+, every formula has ... highest standard. , These products are also: Gluten Free, Non-GMO, Vegan, Soy ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, the ... medical article to the newly revamped Cosmetic Town journal section, featuring ... transplant procedure known as Follicular Unit Extraction (FUE). , Dr. Mohebi ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... R.I. , Sept. 18, 2017 /PRNewswire/ ... the fields of bioinformatics and immune engineering, ... a protective avian influenza A (H7N9) vaccine. ... distantly related to seasonal influenza and presents ... rely on prior exposure to be effective. ...
(Date:9/12/2017)... Sept. 12, 2017   EcoVadis , the leading platform for environmental, ... first annual edition of its Global CSR Risk and Performance Index. The ... EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 data points across ... ... ...
(Date:9/12/2017)...  ValGenesis Inc., the global leader in Enterprise ... announce the appointment of Dr. Ajaz Hussain ... Directors and Chairman of Advisory Board beginning September ... to manage their entire validation lifecycle process electronically ... process. Furthermore, ValGenesis VLMS enables rigorous compliance, helps ...
Breaking Medicine Technology: