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Depression Heightens Sensitivity to Pain
Date:11/7/2008

in areas of their brain, including the right amygdala -- a brain region tied to emotional responses. This increased activity also correlated to higher helplessness scores on the questionnaires of the patients with depression.

"Future studies that directly examine whether maladaptive response to pain in major depressive disorder is due to emotional allodynia [a pain response to a non-painful stimulus], maladaptive control responses, lack of resilience and/or ineffectual recruitment of positive energy resources will further our understanding of pain-depression comorbidity," the authors concluded.

More information

The U.S. National Institute of Health has more about depression.



-- Kevin McKeever



SOURCE: JAMA Archives journals, news release, Nov. 3, 2008


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