Navigation Links
Depression After a Heart Attack Dangerous for Years
Date:3/7/2008

Study finds long-lasting increased risk of death, but no clear explanation why

FRIDAY, March 7 (HealthDay News) -- The increased risk of death associated with depression after a heart attack persists for at least five years, a study finds.

"We've known for a number of years that depression increases the risk of mortality as well as morbidity [illness] after a heart attack for at least three to six months," said study author Robert M. Carney, a professor of psychiatry at Washington University School of Medicine in St. Louis. "We assumed that we would find a decline in risk, but that was not what we found. The risk remained worse after five years."

Carney and his colleagues followed more than 750 people after their heart attacks, according to their report in the current online issue of the Journal of Affective Disorders. Using diagnostic interviews rather than the self-reporting common in most such studies, the researchers determined that 163 had major depression, and 195 had minor depression. Over the five-year study, the death rate was 87 percent higher for those with major depression and 76 percent higher for those with any form of depression.

In real numbers, 62 people diagnosed with depression died during the study, while 44 non-depressed heart attack patients died.

Why depression should increase the risk of dying is a mystery, Carney said. "We think that because depression is a chronic and recurrent problem, the factors causing that risk recur over time," he said. "But we don't know the mechanism."

The researchers have started a trial to determine whether the omega-3 fatty acids that are found in fish oil can reduce that risk. Heart patients are being given an antidepressant drug and a special formulation of omega-3 fatty acids, comparing them with a similar group that gets only an antidepressant.

"A number of studies over the years have found an inverse relationship between the amount of fish people eat and depression," Carney said. "The advantage of giving them in heart disease is that they have an effect on the cardiovascular system as well."

The major finding of the study and the use of omega-3 fatty acids are already in the mainstream of research on depression and heart disease, said Dr. Alexander H. Glassman, a professor of psychiatry at Columbia University Medical Center in New York City.

"There is a torrent of information that depression in relation to vascular disease worsens the outcome," Glassman said. "If you look at post-stroke patients, you find the same data. If you look at heart failure, depression has a similar effect on mortality."

The value of the study is that it had the longest follow-up of any trial using diagnostic interviews, which are regarded as more accurate than self-reporting, Glassman said. "It makes the evidence firmer and extends the evidence," he explained.

The use of omega-3 fatty acids is "a hot issue," being tried in cardiac and non-cardiac cases, Glassman said. "It is a logical thing to do," he added.

The study and the omega-3 trial will still leave some major issues about depression and heart disease open, Glassman said.

"The two key questions that remain are: Does treating depression make the outcome better? And what is it about depression that is causing the problem in the first place?" he said.

More information

Advice on depression after a heart attack is offered by the American Academy of Family Physicians.



SOURCES: Robert M. Carney, Ph.D., professor, psychiatry, Washington University School of Medicine in St. Louis; Alexander H. Glassman, M.D., professor, psychiatry, Columbia University Medcial Center, New York City; March 2008, Journal of Affective Disorders, online


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Older Men With Low Testosterone Face Greater Depression Risk
2. Depression Raised Risk of Subsequent Pregnancies Among Black Teen Moms
3. Clinical depression raises risk of death for heart attack patients years after attack
4. Dementia diagnosis brings relief, not depression
5. BlueChoice HealthPlan Helps Coordinate Postpartum Depression Conference
6. Comparison of venlafaxine and SSRIs in the treatment of depression
7. Doctors should watch for depression in arthritis patients
8. Study: low-income women more likely to suffer from postpartum depression
9. As depression symptoms improve with antidepressants, hopelessness can linger
10. Male births are more likely to reduce quality of life and increase severe post-natal depression
11. Depression in the Elderly is Complicated but Treatable, From the Harvard Mental Health Letter
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Depression After a Heart Attack Dangerous for Years
(Date:4/30/2017)... ... April 30, 2017 , ... ... the importance of substantially reducing melanoma and non-melanoma skin cancer through education by ... a collaboration between the American Academy of Dermatology and Pediatric Sun Protection Foundation, ...
(Date:4/30/2017)... Aliso Viejo, CA (PRWEB) , ... April 30, ... ... liquid animations created exclusively for use in Final Cut Pro X. Editors can ... bursts and more. Easily change the highlights, mid levels and shadows using simple ...
(Date:4/30/2017)... Louis, MO (PRWEB) , ... April 30, 2017 , ... ... a sharp increase in projected attendance for this year’s physician career fairs, with this ... , The complete schedule for the 2017 calendar year of national physician career fairs ...
(Date:4/30/2017)... , ... April 30, 2017 , ... San Francisco Dental ... to announce an updated blog post on the continual issue of the importance of ... seek a second opinion before dental surgery, but this can be a serious mistake. ...
(Date:4/29/2017)... ... April 29, 2017 , ... BECK ... launch of DonorBridge, its process and engagement analytics application built specifically for ... industry expertise with predictive analytics to help nonprofits operate more intelligently and ...
Breaking Medicine News(10 mins):
(Date:4/28/2017)... Inc. ("Hill-Rom") (NYSE: HRC ) today ... ended March 31, 2017, and raised its outlook ... guidance reflect the contribution from the Mortara Instrument ... 14, 2017.  For the fiscal second ... share compared to $0.33 per diluted share in ...
(Date:4/26/2017)... Phoenix Marketing Solutions ( Phoenix ) ... mission of transforming science into clinical practice. During a time ... innovative approach supports the life sciences industry by ... in science and medicine — which ultimately improves lives. ... 2002 by Tracy Doyle and Angela Fiordilino ...
(Date:4/25/2017)... Endo International plc (NASDAQ: ENDP ) will announce its ... management team will host a conference call and webcast before the ... The dial-in number to access the call is U.S./ Canada ... 6086379. Please dial in 10 minutes prior to the scheduled start ... call will be available from May 9, 2017 at 11:30 a.m. ...
Breaking Medicine Technology: