Navigation Links
Depression After a Heart Attack Dangerous for Years
Date:3/7/2008

Study finds long-lasting increased risk of death, but no clear explanation why

FRIDAY, March 7 (HealthDay News) -- The increased risk of death associated with depression after a heart attack persists for at least five years, a study finds.

"We've known for a number of years that depression increases the risk of mortality as well as morbidity [illness] after a heart attack for at least three to six months," said study author Robert M. Carney, a professor of psychiatry at Washington University School of Medicine in St. Louis. "We assumed that we would find a decline in risk, but that was not what we found. The risk remained worse after five years."

Carney and his colleagues followed more than 750 people after their heart attacks, according to their report in the current online issue of the Journal of Affective Disorders. Using diagnostic interviews rather than the self-reporting common in most such studies, the researchers determined that 163 had major depression, and 195 had minor depression. Over the five-year study, the death rate was 87 percent higher for those with major depression and 76 percent higher for those with any form of depression.

In real numbers, 62 people diagnosed with depression died during the study, while 44 non-depressed heart attack patients died.

Why depression should increase the risk of dying is a mystery, Carney said. "We think that because depression is a chronic and recurrent problem, the factors causing that risk recur over time," he said. "But we don't know the mechanism."

The researchers have started a trial to determine whether the omega-3 fatty acids that are found in fish oil can reduce that risk. Heart patients are being given an antidepressant drug and a special formulation of omega-3 fatty acids, comparing them with a similar group that gets only an antidepressant.

"A number of studies over the years have found an inverse relationship between the amount of fish people eat and depression," Carney said. "The advantage of giving them in heart disease is that they have an effect on the cardiovascular system as well."

The major finding of the study and the use of omega-3 fatty acids are already in the mainstream of research on depression and heart disease, said Dr. Alexander H. Glassman, a professor of psychiatry at Columbia University Medical Center in New York City.

"There is a torrent of information that depression in relation to vascular disease worsens the outcome," Glassman said. "If you look at post-stroke patients, you find the same data. If you look at heart failure, depression has a similar effect on mortality."

The value of the study is that it had the longest follow-up of any trial using diagnostic interviews, which are regarded as more accurate than self-reporting, Glassman said. "It makes the evidence firmer and extends the evidence," he explained.

The use of omega-3 fatty acids is "a hot issue," being tried in cardiac and non-cardiac cases, Glassman said. "It is a logical thing to do," he added.

The study and the omega-3 trial will still leave some major issues about depression and heart disease open, Glassman said.

"The two key questions that remain are: Does treating depression make the outcome better? And what is it about depression that is causing the problem in the first place?" he said.

More information

Advice on depression after a heart attack is offered by the American Academy of Family Physicians.



SOURCES: Robert M. Carney, Ph.D., professor, psychiatry, Washington University School of Medicine in St. Louis; Alexander H. Glassman, M.D., professor, psychiatry, Columbia University Medcial Center, New York City; March 2008, Journal of Affective Disorders, online


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Older Men With Low Testosterone Face Greater Depression Risk
2. Depression Raised Risk of Subsequent Pregnancies Among Black Teen Moms
3. Clinical depression raises risk of death for heart attack patients years after attack
4. Dementia diagnosis brings relief, not depression
5. BlueChoice HealthPlan Helps Coordinate Postpartum Depression Conference
6. Comparison of venlafaxine and SSRIs in the treatment of depression
7. Doctors should watch for depression in arthritis patients
8. Study: low-income women more likely to suffer from postpartum depression
9. As depression symptoms improve with antidepressants, hopelessness can linger
10. Male births are more likely to reduce quality of life and increase severe post-natal depression
11. Depression in the Elderly is Complicated but Treatable, From the Harvard Mental Health Letter
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Depression After a Heart Attack Dangerous for Years
(Date:2/28/2017)... SC (PRWEB) , ... February 28, 2017 , ... ... is the premiere organization in North America for the scientific development, healthcare training ... its 2017 Annual Meeting & Scientific Session on September 16-17 in Greenville, SC ...
(Date:2/28/2017)... Salt Lake City, Utah (PRWEB) , ... February 28, 2017 , ... ... Heart Month is a time for everyone to reaffirm their commitment to improving cardiovascular ... leading cause of death for men and women. Every year, one in four deaths ...
(Date:2/28/2017)... ... February 28, 2017 , ... ... from 4:30-5:30 p.m. at the 11th Annual RISE Nashville Summit. RISE Nashville is ... performance analytics, and engagement strategies. , The discussion will include best practices for ...
(Date:2/27/2017)... Austin, TX (PRWEB) , ... February 27, 2017 , ... ... of a large medical group. But his impoverished upbringing and life experiences could have ... to Become a Physician: Insightful and Inspirational Tales of Parenting, Perseverance and Pediatrics,” Dr. ...
(Date:2/27/2017)... ... ... not your typical author. She went from working as a movie extra on Bill Murray’s ... she isn’t swimming as a performing mermaid. , Her book isn’t typical either. In Carothers’ ... comedic look at the dysfunctions of God’s family, before Lucifer was sent to hell. ...
Breaking Medicine News(10 mins):
(Date:2/28/2017)... ... Markets has announced the addition of the "Ovarian Cancer Drugs Price ... The latest research Ovarian Cancer Drugs Price Analysis and Strategies - ... market. The research answers the following questions: ... their clinical attributes? How are they positioned in the Global Ovarian Cancer ...
(Date:2/28/2017)... , Feb. 28, 2017  Rigel Pharmaceuticals, Inc. ... it will report its fourth quarter and year ... March 7, 2017.  Rigel senior management will follow ... webcast at 5:00pm Eastern Time (2:00pm Pacific Time) ... can access the live conference call by dialing ...
(Date:2/28/2017)... , February 27, 2017 ... BioMedical assets for potential ... LOI contemplates capital infusion into Amarantus to assist ... Amarantus names four new appointees to its Board of Directors and ... SeD Biomedical Inc. (SeD Biomedical) , a ...
Breaking Medicine Technology: