Navigation Links
Demographic and clinical factors appear associated with survival in patients with Parkinson's disease
Date:1/2/2012

CHICAGO Demographics and clinical factors appear to be associated with survival in patients with Parkinson disease (PD), and the presence of dementia is associated with a significant increase in mortality, according to a report in the January issue of Archives of Neurology, one of the JAMA/Archives journals.

Although Parkinson disease is a common neurodegenerative disease among the elderly, there are conflicting data on the survival rates of patients with this disease, according to background information in the article.

Allison W. Willis, M.D., from Washington University School of Medicine, St. Louis, and colleagues conducted a nationwide retrospective cohort study of 138,000 Medicare beneficiaries with incident Parkinson disease who were identified in 2002 and followed up through 2008.

Sex and race "significantly predicted" survival, the researchers note. Patients who were women, Hispanic or Asian had a lower adjusted risk of death than white men. During the six-year study, 64 percent of patients with Parkinson disease died, with black patients having the highest crude death rate (66.4 percent), followed by white patients (64.6 percent), Hispanics (55.4 percent) and Asian patients (50.8 percent).

Dementia was diagnosed in 69.6 percent of the study population by the end of the study period and the highest frequency was found in black patients (78.2 percent) followed by Hispanics (73.1 percent). White and Asian patients with PD had lower, similar rates of dementia at 69 percent and 66.8 percent, respectively.

Patients with Parkinson disease and dementia had a greater likelihood of death than those without dementia. The researchers also note that patients with terminal Parkinson disease were hospitalized frequently for cardiovascular disease and infection but rarely for Parkinson disease. They also suggest Parkinson patients living in urban high industrial metal emission areas had a slightly higher adjusted risk of death, but researchers suggest more work is needed to understand if environmental exposures can influence the course of Parkinson disease or survival.

"We demonstrate that dementia occurs commonly in patients with incident PD 65 years and older; this had the strongest effect on age-adjusted survival among the variables that we studied," the authors conclude. "Our data highlight the need for prevention of or treatment for dementia in patients with PD because of its effect on survival," the authors conclude.


'/>"/>

Contact: Joni Westerhouse
westerhousej@wustl.edu
314-286-0120
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Researchers find that sociodemographic characteristics are related to a patients willingness to participate in cancer screenings
2. Demographic disparities found among children with frequent ear infections
3. Demographics cloud optimism on black violent crime decrease
4. ESF awards 13th European Latsis Prize to James Vaupel on pioneering demographic research
5. Stethoscope App gives iPhone New Clinical Skills
6. Sunquest Introduces Integrated Clinical Environment Physician Portal Solution in US
7. Almac Launches New STEMS System to Transform Temperature Controlled Shipment Monitoring in Clinical Trials
8. Clinical trial underway: Miniature ultrasound device could revolutionize pain relief
9. Michael J. Fox Foundation Awards $1.1 Million For Clinical Trial of Transdermal Nicotine as Disease-Modifying Treatment For Parkinsons
10. NOVAVAX Presents Positive Clinical Results at The World Health Organization Conference, Geneva, Switzerland
11. UCLA Health System Presents: How to Successfully Implement a Clinical Portal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2016)... ... February 11, 2016 , ... ... speaker, trainer and author Ray Clarke poses a question as a challenge for ... In his book, "Being in the Being" (published by Partridge Singapore), Clarke explores ...
(Date:2/11/2016)... (PRWEB) , ... February 11, 2016 , ... Colorado spine ... as one of 334 spine surgeons to know in 2016 . The list ... the field of spine surgery. , Dr. Corenman understands the importance of clinical ...
(Date:2/11/2016)... Rock, AR (PRWEB) , ... February 11, 2016 , ... ... in their community by announcing a new fundraiser in support of a local boy ... also hopes the campaign will bring awareness to, and rally support for, all local ...
(Date:2/11/2016)... ... February 11, 2016 , ... ... the American Academy of Dermatology Annual Meeting at the Walter E. Washington Convention ... raise awareness for both the condition of hyperhidrosis (excessive sweating) and its treatment ...
(Date:2/11/2016)... ... February 11, 2016 , ... The book, “Computers Should Just Work!”, provides ... to ask your IT consultant before signing a contract and how to spot an ... “With companies relying heavily on e-mail and technology, it’s more important than ever to ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... The primary goal of this research is ... the usage of liquid biopsy. Key information the survey ... Timeframe of liquid biopsy adoption amidst future users - ... type - Sample inflow to conduct liquid biopsy tests ... and so on. - Correlation analysis of sample type ...
(Date:2/11/2016)... Feb. 11, 2016 Laboratory glassware ... in laboratories. These may range from microscope slides to ... is made from borosilicate glass because of its low ... the other hand, started gaining popularity over the past ... to replace glass with plastic in several applications due ...
(Date:2/11/2016)... -- Governor Andrew M. Cuomo today announced a major expansion ... Western New York . This announcement, made ... includes a major expansion of Athenex,s North American headquarters ... , as well as the creation of a state-of-the-art, ... . The combined projects are expected to yield ...
Breaking Medicine Technology: