Navigation Links
Demographic and clinical factors appear associated with survival in patients with Parkinson's disease
Date:1/2/2012

CHICAGO Demographics and clinical factors appear to be associated with survival in patients with Parkinson disease (PD), and the presence of dementia is associated with a significant increase in mortality, according to a report in the January issue of Archives of Neurology, one of the JAMA/Archives journals.

Although Parkinson disease is a common neurodegenerative disease among the elderly, there are conflicting data on the survival rates of patients with this disease, according to background information in the article.

Allison W. Willis, M.D., from Washington University School of Medicine, St. Louis, and colleagues conducted a nationwide retrospective cohort study of 138,000 Medicare beneficiaries with incident Parkinson disease who were identified in 2002 and followed up through 2008.

Sex and race "significantly predicted" survival, the researchers note. Patients who were women, Hispanic or Asian had a lower adjusted risk of death than white men. During the six-year study, 64 percent of patients with Parkinson disease died, with black patients having the highest crude death rate (66.4 percent), followed by white patients (64.6 percent), Hispanics (55.4 percent) and Asian patients (50.8 percent).

Dementia was diagnosed in 69.6 percent of the study population by the end of the study period and the highest frequency was found in black patients (78.2 percent) followed by Hispanics (73.1 percent). White and Asian patients with PD had lower, similar rates of dementia at 69 percent and 66.8 percent, respectively.

Patients with Parkinson disease and dementia had a greater likelihood of death than those without dementia. The researchers also note that patients with terminal Parkinson disease were hospitalized frequently for cardiovascular disease and infection but rarely for Parkinson disease. They also suggest Parkinson patients living in urban high industrial metal emission areas had a slightly higher adjusted risk of death, but researchers suggest more work is needed to understand if environmental exposures can influence the course of Parkinson disease or survival.

"We demonstrate that dementia occurs commonly in patients with incident PD 65 years and older; this had the strongest effect on age-adjusted survival among the variables that we studied," the authors conclude. "Our data highlight the need for prevention of or treatment for dementia in patients with PD because of its effect on survival," the authors conclude.


'/>"/>

Contact: Joni Westerhouse
westerhousej@wustl.edu
314-286-0120
JAMA and Archives Journals
Source:Eurekalert

Related medicine news :

1. Researchers find that sociodemographic characteristics are related to a patients willingness to participate in cancer screenings
2. Demographic disparities found among children with frequent ear infections
3. Demographics cloud optimism on black violent crime decrease
4. ESF awards 13th European Latsis Prize to James Vaupel on pioneering demographic research
5. Stethoscope App gives iPhone New Clinical Skills
6. Sunquest Introduces Integrated Clinical Environment Physician Portal Solution in US
7. Almac Launches New STEMS System to Transform Temperature Controlled Shipment Monitoring in Clinical Trials
8. Clinical trial underway: Miniature ultrasound device could revolutionize pain relief
9. Michael J. Fox Foundation Awards $1.1 Million For Clinical Trial of Transdermal Nicotine as Disease-Modifying Treatment For Parkinsons
10. NOVAVAX Presents Positive Clinical Results at The World Health Organization Conference, Geneva, Switzerland
11. UCLA Health System Presents: How to Successfully Implement a Clinical Portal
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/2/2016)... ... December 02, 2016 , ... Universal Medical Systems, ... and the first company to offer robotic imaging to veterinary medicine is sponsoring ... # 941 for the American Association of Equine Practitioners 62nd Annual Convention from ...
(Date:12/2/2016)... ... ... "Pro3rd Accents Volume 2 is a set of 30 accented lower third ... a few clicks of the mouse," said Christina Austin - CEO of Pixel Film ... various styles with accented animations, rigid boxes, simplistic lines, and more. In Addition, users ...
(Date:12/2/2016)... ... December 02, 2016 , ... Date aired: November 28, ... 2 Diabetes: The Owner’s Manual, http://realtimepressrelease.com/press-releases-tagged-with/daryl-wein , Sharon Kleyne, America’s ... Global Climate Change and Your Health radio program syndicated on Voice of America, ...
(Date:11/30/2016)... ... November 30, 2016 , ... "I hate when the mixture of saliva ... teeth," said an inventor from Bridgewater, N.J. "I thought that there had to be ... , He developed the patent-pending DEFLECTOR to prevent saliva and toothpaste from running down ...
(Date:11/30/2016)... ... November 30, 2016 , ... In recent policy debates, increasing ... public policymakers and system stakeholders in many states. To help them understand this ... Index for Workers’ Compensation, Eighth Edition (MPI-WC) . , “If you are a ...
Breaking Medicine News(10 mins):
(Date:12/2/2016)... -- CVS Health Corporation (NYSE: CVS ) ... December 15, 2016, beginning at 8:00 a.m. (ET). Senior members ... in-depth review of the company,s strategies to drive long-term ... discuss 2017 earnings guidance during the event. ... be broadcast simultaneously on the Investor Relations portion of ...
(Date:12/2/2016)... 2, 2016 On Thursday, the NASDAQ ... red, while the Dow Jones Industrial Average managed to stay ... US markets, which prompted Stock-callers this morning to look at ... NUVA ), Smith & Nephew PLC (NYSE: ... ), and Cesca Therapeutics Inc. (NASDAQ: KOOL ). ...
(Date:12/2/2016)... , Dec. 1, 2016 Around the ... country, region and each habitable land present over earth. ... every individual once in a life time this is ... care available until now. Given the steady increase in ... together with the spiraling healthcare costs of treatment, there ...
Breaking Medicine Technology: