Navigation Links
Degenerative cervical spine disease may not progress over time
Date:2/19/2013

Philadelphia, Pa. (February 19, 2013) - Follow-up data on patients with degenerative disease of the upper (cervical) spinal vertebrae show little or no evidence of worsening degeneration over time, according to a study in the February 15 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

For many patients with "unstable" cervical degenerative spondylolisthesis, observation may be a better choice than surgery, according to the new research by Dr Moon Soo Park and colleagues of Medical College of Hallym University, Republic of Korea. They write, "Our results suggest that the majority of these patients may be stable and do not develop progression of disease or catastrophic neurologic deficits."

Is Unstable Spondylolisthesis Really Unstable?

The researchers analyzed the "natural history" of cervical degenerative spondylolisthesis in 27 patients. Degenerative spondylolisthesis refers to "slipped" vertebrae caused by bone degeneration. Because spondylolisthesis is commonly thought to result in instability of the cervical spine, spinal fusion surgery (arthrodesis) is sometimes considered the appropriate treatment.

The 16 men and 11 women in the study underwent cervical spine radiographs (x-rays) on two occasions at least two years apart. The patients' average age at the time of the initial radiograph was 59 years; average time to the follow-up radiographs was 39 months. Measurements on the paired radiographs were carefully compared to determine whether and how much the cervical slippage increased over time.

Initial x-rays showed "instability"at least two millimeters of displacement between vertebraein several patients. However, during follow-up, none of the patients had further progression, defined as additional displacement of two millimeters or more. The average progression was only about one-half millimeter.

Twenty-one patients had backward displacement ("retrolisthesis") of the cervical vertebrae, while six had forward displacement ("anterolisthesis"). The patients with retrolisthesis had somewhat greater slippage during follow-up; however, none had a dislocation or suffered neurological damage.

No Progression of 'Slippage' or Symptoms

Of 16 patients who had symptoms such as neck pain or sensory abnormalities at the initial visit, most were successfully managed without surgery. Of the 11 patients who were initially symptom-free, none developed symptoms during follow-up.

The study is one of the few to look at the "natural history" of cervical spondylolisthesis. The results suggest that, at medium-term follow-up, the conditions appears to be "relatively stable" in most patients. Dr Park and colleagues write, "This begs the question, if an 'unstable' listhesis does fine without treatment, is it really unstable? Our results suggest that the majority of these patients may be stable and do not develop progression of disease or catastrophic neurologic deficits."

The researchers acknowledge some important limitations of their studyparticularly the small number of patients and relatively short follow-up. However, the results suggest that, for many patients, cervical spondylolisthesis is a non-progressive condition that does not necessarily require surgical treatment. Dr Park and coauthors conclude, "In the absence of neurologic symptoms, we recommend observation of patients with degenerative spondylolistheses of the cervical spine."


'/>"/>

Contact: Connie Hughes
connie.hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health
Source:Eurekalert

Related medicine news :

1. New understanding can lead to srategies for dealing with neurodegenerative diseases
2. Researchers find chemical switches for neurodegenerative diseases
3. LA BioMeds Dr. Patricia Dickson researching treatments for neurodegenerative disorders
4. Bascom Palmer Eye Institute announces breakthrough for degenerative vision disorder
5. Avastin May Help Boost Survival With Aggressive Cervical Cancer: Study
6. Cunningham Financial Group Encourages Women to Celebrate “Cervical Health Awareness Month” by Following Important Health Tips
7. Cervical Health Awareness Month 2013: Maternal & Family Health Services Focuses on Access to Reproductive Healthcare to Reduce Cervical Cancer
8. How Cervical Cancer Vaccines Came to Be
9. Research makes connetion between tubal ligation and increase in cervical cancer rates
10. Cervical cancer screening in less-developed areas should be tailored to local conditions
11. New test may improve cervical cancer detection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/27/2016)... ... ... Aimed at nurses and employees in the health care world, this installment ... nursing and health care industry. It also provides insight to the developing trends and ... As the nursing industry is coming out of one of the biggest recessions in ...
(Date:5/26/2016)... ... 2016 , ... There are many ways to cook a hot dog, but ... Americans prefer their dogs straight off the grill. Of the 90 percent of Americans ... to cook a hot dog, far outpacing other cooking methods such as steaming (12 ...
(Date:5/26/2016)... ... 26, 2016 , ... Georgia State University College of Law ... , Answering to the increasing demand for curricular specializations, the Certificate in Intellectual ... and land use law. ,  , “The demand for lawyers with specific knowledge ...
(Date:5/26/2016)... Pittsburgh, PA (PRWEB) , ... May 26, 2016 ... ... transplantation, and one that has a significant negative impact on long-term patient survival, ... to date. The results, published online this week in the Journal of Thoracic ...
(Date:5/26/2016)... NY (PRWEB) , ... May 26, 2016 , ... ... Hereditary Retinal Degeneration” for the Foundation Fighting Blindness, Long Island Chapter on June ... to the public. , Dr. Maisel, founder of Retina Group of New ...
Breaking Medicine News(10 mins):
(Date:5/26/2016)... -- According to a new market report published ... Industry Analysis, Size, Share, Growth, Trends, and Forecast 2015 - ... valued at US$ 5.89 Bn in 2014 and is anticipated ... 2023 to reach US$ 7.99 Bn in 2023. ... free drug delivery devices and the market is estimated based ...
(Date:5/26/2016)... 2016   Change Healthcare , a ... solutions and technology-enabled services designed to enable ... a strategic channel partnership with SourceMed, the ... and revenue cycle management services that empower ... clinics to optimize revenue, operational efficiency and ...
(Date:5/25/2016)... PUNE, India , May 25, 2016 ... "Medical Animation Market by Type (3D, 2D, 4D), by ... Patient Education), by End User (Medical Device Manufacturers, Hospitals/ ... report studies the global Medical Animation Market for the ... expected to reach USD 301.3 Million by 2021 from ...
Breaking Medicine Technology: