Navigation Links
Degenerative cervical spine disease may not progress over time
Date:2/19/2013

Philadelphia, Pa. (February 19, 2013) - Follow-up data on patients with degenerative disease of the upper (cervical) spinal vertebrae show little or no evidence of worsening degeneration over time, according to a study in the February 15 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

For many patients with "unstable" cervical degenerative spondylolisthesis, observation may be a better choice than surgery, according to the new research by Dr Moon Soo Park and colleagues of Medical College of Hallym University, Republic of Korea. They write, "Our results suggest that the majority of these patients may be stable and do not develop progression of disease or catastrophic neurologic deficits."

Is Unstable Spondylolisthesis Really Unstable?

The researchers analyzed the "natural history" of cervical degenerative spondylolisthesis in 27 patients. Degenerative spondylolisthesis refers to "slipped" vertebrae caused by bone degeneration. Because spondylolisthesis is commonly thought to result in instability of the cervical spine, spinal fusion surgery (arthrodesis) is sometimes considered the appropriate treatment.

The 16 men and 11 women in the study underwent cervical spine radiographs (x-rays) on two occasions at least two years apart. The patients' average age at the time of the initial radiograph was 59 years; average time to the follow-up radiographs was 39 months. Measurements on the paired radiographs were carefully compared to determine whether and how much the cervical slippage increased over time.

Initial x-rays showed "instability"at least two millimeters of displacement between vertebraein several patients. However, during follow-up, none of the patients had further progression, defined as additional displacement of two millimeters or more. The average progression was only about one-half millimeter.

Twenty-one patients had backward displacement ("retrolisthesis") of the cervical vertebrae, while six had forward displacement ("anterolisthesis"). The patients with retrolisthesis had somewhat greater slippage during follow-up; however, none had a dislocation or suffered neurological damage.

No Progression of 'Slippage' or Symptoms

Of 16 patients who had symptoms such as neck pain or sensory abnormalities at the initial visit, most were successfully managed without surgery. Of the 11 patients who were initially symptom-free, none developed symptoms during follow-up.

The study is one of the few to look at the "natural history" of cervical spondylolisthesis. The results suggest that, at medium-term follow-up, the conditions appears to be "relatively stable" in most patients. Dr Park and colleagues write, "This begs the question, if an 'unstable' listhesis does fine without treatment, is it really unstable? Our results suggest that the majority of these patients may be stable and do not develop progression of disease or catastrophic neurologic deficits."

The researchers acknowledge some important limitations of their studyparticularly the small number of patients and relatively short follow-up. However, the results suggest that, for many patients, cervical spondylolisthesis is a non-progressive condition that does not necessarily require surgical treatment. Dr Park and coauthors conclude, "In the absence of neurologic symptoms, we recommend observation of patients with degenerative spondylolistheses of the cervical spine."


'/>"/>

Contact: Connie Hughes
connie.hughes@wolterskluwer.com
646-674-6348
Wolters Kluwer Health
Source:Eurekalert

Related medicine news :

1. New understanding can lead to srategies for dealing with neurodegenerative diseases
2. Researchers find chemical switches for neurodegenerative diseases
3. LA BioMeds Dr. Patricia Dickson researching treatments for neurodegenerative disorders
4. Bascom Palmer Eye Institute announces breakthrough for degenerative vision disorder
5. Avastin May Help Boost Survival With Aggressive Cervical Cancer: Study
6. Cunningham Financial Group Encourages Women to Celebrate “Cervical Health Awareness Month” by Following Important Health Tips
7. Cervical Health Awareness Month 2013: Maternal & Family Health Services Focuses on Access to Reproductive Healthcare to Reduce Cervical Cancer
8. How Cervical Cancer Vaccines Came to Be
9. Research makes connetion between tubal ligation and increase in cervical cancer rates
10. Cervical cancer screening in less-developed areas should be tailored to local conditions
11. New test may improve cervical cancer detection
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/28/2017)... NY (PRWEB) , ... April 28, 2017 , ... ... celebrating its 5th anniversary. SearchLight is the premier online modeling resource for fluorescence ... more than 30,000 active users during last 5 years spanning the globe, SearchLight ...
(Date:4/27/2017)... ... April 27, 2017 , ... Healthcare companies are trying to meet talent ... an outdated healthcare executive resume. , “If you’re a healthcare executive open to new ... wondering if it’s as ready as you are for a new job search. I’ve ...
(Date:4/27/2017)... ... April 27, 2017 , ... SyncDog, ... sponsorship at MobileIron Live! 2017 in Santa Clara, California. Each year, ... educational approach to helping organizations maximize the benefits of mobility in their operations ...
(Date:4/27/2017)... ... April 27, 2017 , ... Plastic Surgery Associates is ... been asked to present at the upcoming Aesthetic Meeting. Held in San Diego, at ... Drs. Furnas and Canales will lend their expertise to the Premier Global Hot Topics ...
(Date:4/26/2017)... ... April 26, 2017 , ... ... the ATA 2017 President’s Awards recipients, comprised of organizations and individuals who ... , The ATA 2017 President’s Awards recognize individuals and organizations on ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... Research and Markets has announced the addition of ... By Service (Manufacturing, Research), By Country, (Brazil, Mexico, Colombia, Argentina, ... to their offering. ... The Latin American pharmaceutical contract manufacturing services market is anticipated ... drug registration cost in Latin American countries and continuous economic ...
(Date:4/19/2017)... YORK , April 19, 2017 Global ... drainage devices are tubes used to remove excess liquid ... blood, serum, pus, urine, bile or lymph. Surgical drains ... of surgery such as orthopedics surgery, cardiovascular surgery, neurosurgery, ... is prophylactic post-surgery to prevent accumulation of fluid e.g. ...
(Date:4/19/2017)... Companion animal vaccines ... pets such as canine, avian and feline. ... such as Attenuated Live Vaccines, Conjugate Vaccines, Inactivated ... Recombinant Vaccines. Attenuated live vaccines are derived from ... have been weakend under laboratory conditions. Conjugate vaccines ...
Breaking Medicine Technology: