Navigation Links
Definitive study confirms chemo benefit in postmenopausal breast cancer
Date:12/10/2009

ast cancer cases in the U.S.

"There's nothing magic about the biology being different in lymph node-negative versus lymph node-positive breast cancer," says Albain. When it comes to predicting benefit from chemotherapy, "our data suggest that it doesn't seem to matter whether the lymph nodes are involved or not, but the recurrence score on the genetic assay does matter. It identifies for us a group of patients who have a distinct tumor biology, for whom chemotherapy may not reduce the chances of recurrence even though their risk is high."

Currently, several months of chemotherapy after surgery is the standard of care for a patient with node-positive breast cancer, regardless of the hormone receptor or other biomarker status in her tumor tissue. Indeed, chemotherapy in this setting has been credited in part for a marked decline in breast cancer mortality over the last 20 years. But if validated by later studies, the results reported by the SWOG investigators would mean that many of these patients are being treated needlessly, since they do not benefit from the chemotherapy.

The researchers stress that these results only pertain to patients with estrogen receptor-positive breast cancers, and that more work needs to be done to confirm the findings before doctors change clinical practice based on them.

"Many aspects of this retrospective study introduce uncertainty into our results and make our conclusions tentative," says Dr. Daniel Hayes of the University of Michigan Medical School, who was senior author on the Lancet Oncology study. "Prospective studies with larger sample sizes are needed to determine who will benefit from chemotherapy added to hormonal therapy and who should avoid chemotherapy altogether."

Hayes adds that the Southwest Oncology Group is now designing such a study.


'/>"/>

Contact: Frank DeSanto
fdesanto@umich.edu
734-998-0114
University of Michigan Health System
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Stryker Announces Definitive Agreement To Acquire Ascent Healthcare Solutions
2. Authentidate Introduces New Interface for Inscrybe Healthcare with Definitive Homecare Solutions CPR+
3. Kimberly-Clark Announces Definitive Agreement to Acquire I-Flow Corporation
4. Definitive Sexual Health Book Released
5. Johnson & Johnson and Elan Corporation plc Announce Definitive Agreement for Alzheimers Immunotherapy Program and Equity Investment
6. Wyeth Files Definitive Proxy Statement and Announces Date for Annual Meeting of Stockholders
7. Triple-S Management Corporation Announces Execution of Definitive Agreement to Acquire Managed Care Portfolio of La Cruz Azul de Puerto Rico, Inc.
8. Express Scripts Announces Definitive Agreement to Acquire WellPoint NextRx Subsidiaries for $4.675 Billion
9. AMICAS Announces Definitive Agreement to Acquire Emageon Inc.
10. Thoratec Announces Definitive Agreement to Acquire HeartWare International For US$282 Million;
11. Indevus Pharmaceuticals Announces Definitive Merger Agreement With Endo Pharmaceuticals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... 2014 (HealthDay News) -- Adults who experienced childhood ... migraine headaches, suggests a study published online Dec. ... "Childhood maltreatment can have long-lasting effects, like associated ... study author Dawn Buse, director of behavioral medicine ... said in a journal news release. "When ...
(Date:12/24/2014)... December 24, 2014 Gluten, a protein ... those who have an intolerance to gluten, causing side ... bloating, migraine headaches, joint pain and fatigue. For this ... plans that deliver safe and fast weight loss ... trigger a gluten allergy reaction. These gluten free diet ...
(Date:12/24/2014)... NY (PRWEB) December 24, 2014 The ... with regards to the various market dynamics such as ... robot assisted arthroscopy, the wait time for U.S. sports ... sports medicine market, and the challenges faced by the ... http://www.researchmoz.us/global-sports-medicine-market-report-2014-edition-report.html , The report also provides an ...
(Date:12/24/2014)... “ Relax Melodies ” was featured ... features the latest and coolest mobile applications on the ... technology expert and host of NewsWatch, conducted the app ... users so they can fall asleep. , According to ... they have some sort of difficulty sleeping. Since that’s ...
(Date:12/24/2014)... York (PRWEB) December 24, 2014 In ... the United States rode bicycles, hand cycles and recumbent ... D.C. in the inaugural CanAm Veterans’ Challenge . ... non-profit World T.E.A.M. Sports about this inspiring ride, is ... more than 50 full color photographs taken during the ...
Breaking Medicine News(10 mins):Health News:Abuse in Childhood Tied to Migraines in Adulthood 2Health News:Diet Doc Adds Gluten Free Diet Plans to Their Stable of Specialized Weight Loss Programs 2Health News:Diet Doc Adds Gluten Free Diet Plans to Their Stable of Specialized Weight Loss Programs 3Health News:Sports Medicine Market Report 2014: Global Industry Analysis, Share, Size, Trends, Growth and Forecast report 2Health News:An Application to Help with Insomnia was Featured on NewsWatch Television on December 19, 2014 2Health News:New Commemorative Book Celebrates CanAm Veterans’ Challenge Bike Ride 2Health News:New Commemorative Book Celebrates CanAm Veterans’ Challenge Bike Ride 3
... Gain MomentumCHICAGO, March 3 Accertify www.accertify.com ... prevention solutions to online merchants, today announced that ... a developer and marketer of scientifically formulated, premium ... blend of the Amazonian acai berry and 18 ...
... March 3 Clarient, Inc. (Nasdaq: ... testing services resource for pathologists, oncologists and the pharmaceutical ... Company has renewed, expanded and extended its senior subordinated ... (NYSE: SFE ), Clarient,s majority shareholder."In the ...
... and software testing firm for medical device makers ... Technical Report, QA Software Automation and Testing. ... software quality assurance project managers tools to analyze ... the right people to automate software quality assurance ...
... accepting entries for the 2009 HealthLeaders Media Marketing Awards Program through May ... in one of 22 categories. , ... Marblehead, MA (PRWEB) March 3, ... 2009 HealthLeaders Media Marketing Awards Program through May 29, 2009. Campaigns ...
... any room, The Flag Company, Inc.,s new ,Feel Good, Light Lenses ... spirits during this trying economical time. , ... (PRWEB) ... that has gripped the nation, the Flag Company, Inc. recently launched ...
... Women,s and Children,s Hospital (KKH) can now opt for a "non-contact" ... almost painless operation to treat uterine fibroids. , ... ... KK Women,s and Children,s Hospital (KKH) can now opt for ...
Cached Medicine News:Health News:MonaVie Chooses Accertify for Online Fraud Prevention 2Health News:Clarient Renews and Expands Mezzanine Credit Facility With Safeguard 2Health News:Clarient Renews and Expands Mezzanine Credit Facility With Safeguard 3Health News:Clarient Renews and Expands Mezzanine Credit Facility With Safeguard 4Health News:For Medical Device Makers, Full Spectrum Software Releases New Software Technical Report, QA Software Automation and Software Testing 2Health News:Entry Period Opens for the 2009 HealthLeaders Media Marketing Awards Program with 11 New Categories 2Health News:Entry Period Opens for the 2009 HealthLeaders Media Marketing Awards Program with 11 New Categories 3Health News:The Flag Company, Inc. Releases 'Feel Good' Light Lenses to Help Counter Gloomy Economic Outlook 2Health News:The Flag Company, Inc. Releases 'Feel Good' Light Lenses to Help Counter Gloomy Economic Outlook 3Health News:Singapore Premier Women's Hospital Offers Contactless Surgery for Uterine Fibroids 2Health News:Singapore Premier Women's Hospital Offers Contactless Surgery for Uterine Fibroids 3Health News:Singapore Premier Women's Hospital Offers Contactless Surgery for Uterine Fibroids 4
(Date:12/24/2014)... PHILADELPHIA , Dec. 23, 2014 ... a medical device company focused on skin permeation, ... that Scott W. Hollander has been ... Mr. Hollander has more than 20 years of ... equipment industries, and most recently served as Vice ...
(Date:12/24/2014)... ResMed (NYSE: RMD ) today announced its victory ... manufacturer BMC Medical Co., Ltd. The International ... infringe ResMed,s patents, and entered an order prohibiting BMC from ... United States : , iVolve nasal mask ... pillows mask , iVolve full face mask ...
(Date:12/24/2014)... LEXINGTON, Mass. , Dec. 23, 2014 /PRNewswire/ ... GEVA ), a biopharmaceutical company developing therapeutic products ... European Medicines Agency (EMA) of the Marketing Authorization ... The EMA recently granted the company,s request for ... the EMA,s regulatory review time.   ...
Breaking Medicine Technology:Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 2Echo Therapeutics Announces Scott W. Hollander as President & Chief Executive Officer 3ResMed Wins Patent Infringement Lawsuit Against Chinese Manufacturer BMC Medical 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 3
... Calif., Nov. 4, 2010 ThermoGenesis Corp. (Nasdaq: ... that process and store adult stem cells, said today that ... million, a 35 percent increase over revenues of $5.2 million ... a separate release today, the Company announced it has signed ...
... 2010 The Society for Biomolecular Sciences, now officially ... Automation and Screening (SLAS), invites students, graduate students, post-doctoral ... Academic Travel Award to be used for the SBS ... Orlando, FL, USA. Applicants must be the ...
Cached Medicine Technology:ThermoGenesis Reports 35 Percent Increase in First Quarter 2011 Revenues, Adds Strategic Advisor and Inks China Distribution Deal With Nanshan Memorial Medical Institute 2ThermoGenesis Reports 35 Percent Increase in First Quarter 2011 Revenues, Adds Strategic Advisor and Inks China Distribution Deal With Nanshan Memorial Medical Institute 3ThermoGenesis Reports 35 Percent Increase in First Quarter 2011 Revenues, Adds Strategic Advisor and Inks China Distribution Deal With Nanshan Memorial Medical Institute 4ThermoGenesis Reports 35 Percent Increase in First Quarter 2011 Revenues, Adds Strategic Advisor and Inks China Distribution Deal With Nanshan Memorial Medical Institute 5ThermoGenesis Reports 35 Percent Increase in First Quarter 2011 Revenues, Adds Strategic Advisor and Inks China Distribution Deal With Nanshan Memorial Medical Institute 6ThermoGenesis Reports 35 Percent Increase in First Quarter 2011 Revenues, Adds Strategic Advisor and Inks China Distribution Deal With Nanshan Memorial Medical Institute 7Applications Now Being Accepted for SBS 17th Annual Conference & Exhibition Academic Travel Awards 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: