Navigation Links
Deficit in Brain Function Puts Teens at Risk of Drug Abuse
Date:3/5/2008

Frontal cortex at center of ability to control impulsive responses, study finds

WEDNESDAY, March 5 (HealthDay News) -- Teens at risk of developing a substance abuse disorder have deficits in frontal brain activation, a U.S. study concludes.

The researchers used functional MRI to study brain activity in 25 participants, ages 12 to 19, as they did an eye movement test. The scientists found a link between increased risk for a substance abuse disorder and shortfalls in executive cognitive function (ECF).

"ECF is basically the control center for governing other cognitive processes," corresponding author Rebecca Landes McNamee, assistant research professor of radiology and bioengineering at the University of Pittsburgh, said in a prepared statement.

"For example, in school, ECF would be engaged in the planning and control process required in answering a question, formulating your response, raising your hand, waiting until you are called upon, and starting your answer. A person with low levels of ECF might blurt out the answer," McNamee said.

"Another example could be interacting with someone on the playground who upsets you. A person with good ECF will think through the actions and consequences of their behavior rather than responding rashly. A person with low levels of ECF may respond with violence."

In this study, the teens did a task that required inhibition of an initial eye movement as well as a voluntary eye realignment to an alternate location. While they did this, fMRI was used to scan activation in different brain regions.

In addition, each adolescent's neurobehavioral disinhibition (ND) -- the ability to control an immediate impulsive response to a given situation -- was assessed, and their drug use/histories were recorded.

"We found that individuals who exhibit a high amount of ND -- that is, do not have a good ability to manage their impulsive responses -- have less brain activity in the frontal cortex, the region of the brain responsible for ECF, during the antisaccade task. In other words, the regions of the brain responsible for these inhibitory processes engaged less energy in individuals with higher ND scores than those with lower ND scores," McNamee said.

One of the key findings of this study, published in the March issue of the journal Alcoholism: Clinical & Experimental Research, is that behaviors and actions are directly related to brain functioning.

"Teachers, caregivers, and other individuals should understand that each adolescent matures at a different rate; they do not always respond like adults, because their brains are not at the same level of functioning as an adult," McNamee said. "Responses and behaviors related to a certain situation are less easy for some adolescents to manage than others."

More information

The Nemours Foundation has more about teens and alcohol and drugs.



-- Robert Preidt



SOURCE: Alcoholism: Clinical & Experimental Research, news release, March 4, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Pedophilia patients are found to have deficits in brain activation
2. ACM Helps Medicaid Programs Comply With Federal Deficit Reduction Act Mandates
3. CDC Study Links Thimerosal in Vaccines to Motor/Phonic Tics and Deficits in Attention, Behavior Control, Verbal IQ
4. Cognitive deficits lead to loss of self among cancer patients
5. Study examines decision-making deficits in older adults
6. Brain region that can be stimulated to reduce the cognitive deficits of sleep deprivation identified
7. Gene therapy trains immune system to destroy brain cancer cells and reverses behavioral deficits
8. Draining away brains toxic protein to stop Alzheimers
9. Vision restoration therapy shown to improve brain activity in brain injured patients
10. Clinical depression linked to abnormal emotional brain circuits
11. Brain imaging reveals breakdown of normal emotional processing
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Deficit in Brain Function Puts Teens at Risk of Drug Abuse
(Date:2/10/2016)... ... February 10, 2016 , ... 10 Best Water ... three leading bottled water brand owners that topped the list as a result of ... optimize conversion. The premier brand was Tibet 5100, a top notch water company that ...
(Date:2/10/2016)... ... ... Ongoing news of the ravages of traumatic brain injury (TBI) among former ... takes a closer look at cases of TBI being managed by their members. The ... the aging population, and identifies the challenges associated with their care. , During the ...
(Date:2/10/2016)... ... 10, 2016 , ... Gout is like no other joint pain. It strikes ... with intense swelling and redness. It is triggered by the crystallization of uric acid ... the most susceptible, according to the February 2016 issue of Harvard Men's Health Watch. ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... ... four time Emmy award winner and inspirational speaker Jan Fox will serve as ... by Speaking Boldly will provide participants with tools to more effectively communicate with ...
(Date:2/10/2016)... ... February 10, 2016 , ... A national ergonomics pioneer ... Expo event March 9-11, 2016. Hosted by Ohio's Bureau of Worker's Compensation, the ... the longest running and largest worker's compensation event in Ohio, organizers of the ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... Calif. , Feb. 10, 2016 /PRNewswire/ ... a synergistic confluence of various technologies that ... propositions, previously unavailable. These opportunities create a ... convergence, in turn, drives the development of ... scenario is characterized by technology convergences, which ...
(Date:2/10/2016)... PRINCETON, New Jersey and OR AKIVA, ... Regentis Biomaterials Ltd., a leader ... of its Series D investment round on February 5, ... Haisco Pharmaceutical Group ("Haisco"), a leading Chinese pharmaceutical ... Medica Partners, SCP Vitalife Partners, Generali Financial Holdings and ...
(Date:2/10/2016)... DIEGO , Feb. 10, 2016 ALSP, Inc. ... , MD as Consultant for Medical Affairs in preparation for ... Michael Pierschbacher , PhD, CEO, stated, "We are pleased ... We look forward to working with an individual of such ... We look forward to drawing deeply on his broad experience ...
Breaking Medicine Technology: